Prenatal maternal stress from a natural disaster predicts dermatoglyphic asymmetry in humans / Suzanne KING in Development and Psychopathology, 21-2 (May 2009)  

Public ISBD [article]  inDevelopment and Psychopathology > 21-2 (May 2009) . - p.343-353 Titre : Prenatal maternal stress from a natural disaster predicts dermatoglyphic asymmetry in humans Type de document : Texte imprimé et/ou numérique Auteurs : Suzanne KING, Auteur ; Michael J. MEANEY, Auteur ; Elaine F. WALKER, Auteur ; Adham MANCINI-MARIE, Auteur ; Alain BRUNET, Auteur ; David P. LAPLANTE, Auteur Année de publication : 2009 Article en page(s) : p.343-353 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Dermatoglyphic asymmetry of fingertip ridge counts is more frequent in schizophrenia patients than normal controls, and may reflect disruptions in fetal development during Weeks 14–22 when fingerprints develop. However, there are no data in humans linking specific adverse events at specific times to dermatoglyphic asymmetries. Our objective was to determine whether prenatal exposure to a natural disaster (1998 Quebec ice storm) during Weeks 14–22 would result in increased dermatoglyphic asymmetry in children, and to determine the roles of maternal objective stress exposure, subjective stress reaction, and postdisaster cortisol. Ridge counts for homologous fingers were scored for 77 children (20 target exposed [Weeks 14–22] and 57 nontarget exposed [exposed during other gestation weeks]). Children in the target group had more than 0.50 SD greater asymmetry than the nontarget group. Within the target group, children whose mothers had high subjective ice storm stress had significantly greater asymmetry than those with lower stress mothers, and maternal postdisaster cortisol had a significant negative correlation with the children's dermatoglyphic asymmetry (r = −.56). Prenatal maternal stress during the period of fingerprint development results in greater dermatoglyphic asymmetry in their children, especially in the face of greater maternal distress. En ligne : http://dx.doi.org/10.1017/s0954579409000364 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=726 [article] Prenatal maternal stress from a natural disaster predicts dermatoglyphic asymmetry in humans [Texte imprimé et/ou numérique] / Suzanne KING, Auteur ; Michael J. MEANEY, Auteur ; Elaine F. WALKER, Auteur ; Adham MANCINI-MARIE, Auteur ; Alain BRUNET, Auteur ; David P. LAPLANTE, Auteur . - 2009 . - p.343-353. Langues : Anglais (eng) in Development and Psychopathology > 21-2 (May 2009) . - p.343-353 Index. décimale : PER Périodiques Résumé : Dermatoglyphic asymmetry of fingertip ridge counts is more frequent in schizophrenia patients than normal controls, and may reflect disruptions in fetal development during Weeks 14–22 when fingerprints develop. However, there are no data in humans linking specific adverse events at specific times to dermatoglyphic asymmetries. Our objective was to determine whether prenatal exposure to a natural disaster (1998 Quebec ice storm) during Weeks 14–22 would result in increased dermatoglyphic asymmetry in children, and to determine the roles of maternal objective stress exposure, subjective stress reaction, and postdisaster cortisol. Ridge counts for homologous fingers were scored for 77 children (20 target exposed [Weeks 14–22] and 57 nontarget exposed [exposed during other gestation weeks]). Children in the target group had more than 0.50 SD greater asymmetry than the nontarget group. Within the target group, children whose mothers had high subjective ice storm stress had significantly greater asymmetry than those with lower stress mothers, and maternal postdisaster cortisol had a significant negative correlation with the children's dermatoglyphic asymmetry (r = −.56). Prenatal maternal stress during the period of fingerprint development results in greater dermatoglyphic asymmetry in their children, especially in the face of greater maternal distress. En ligne : http://dx.doi.org/10.1017/s0954579409000364 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=726

The neuroanatomy of the autistic phenotype / Cherine FAHIM in Research in Autism Spectrum Disorders, 6-2 (April-June 2012)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 6-2 (April-June 2012) . - p.898-906 Titre : The neuroanatomy of the autistic phenotype Type de document : Texte imprimé et/ou numérique Auteurs : Cherine FAHIM, Auteur ; Nagwa A. MEGUID, Auteur ; Neveen H. NASHAAT, Auteur ; Uicheul YOON, Auteur ; Adham MANCINI-MARIE, Auteur ; Alan C. EVANS, Auteur Année de publication : 2012 Article en page(s) : p.898-906 Langues : Anglais (eng) Mots-clés : Autism  Fragile X syndrome  Williams syndrome  Gray matter  White matter  Neuroimaging Index. décimale : PER Périodiques Résumé : The autism phenotype is associated with an excess of brain volume due in part to decreased pruning during development. Here we aimed at assessing brain volume early in development to further elucidate previous findings in autism and determine whether this pattern is restricted to idiopathic autism or shared within the autistic phenotype (fragile X syndrome [FXS]). We investigated brain volume in 37 participants, using the fully automated Civet pipeline anatomical magnetic resonance imaging. 3 groups with intellectual deficiency: autism (AUT); its most associated FXS; and its most opposite Williams syndrome (WS) were compared with each other and with normal controls (NC). We report increased total and regional gray and white matter brain volume in AUT and FXS relative to WS and NC. These findings are discussed in light of the possibilities leading for the enlarged brain volume in children with the AUT phenotype. We speculate that this excess suggests reduced regression of neuronal processes “pruning” in cortical and subcortical regions in AUT/FXS, which may be due to a mutation in specific genes involved in pruning and/or a lack of socio-emotional environmental experience during a critical developmental period. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.11.008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150 [article] The neuroanatomy of the autistic phenotype [Texte imprimé et/ou numérique] / Cherine FAHIM, Auteur ; Nagwa A. MEGUID, Auteur ; Neveen H. NASHAAT, Auteur ; Uicheul YOON, Auteur ; Adham MANCINI-MARIE, Auteur ; Alan C. EVANS, Auteur . - 2012 . - p.898-906. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 6-2 (April-June 2012) . - p.898-906 Mots-clés : Autism  Fragile X syndrome  Williams syndrome  Gray matter  White matter  Neuroimaging Index. décimale : PER Périodiques Résumé : The autism phenotype is associated with an excess of brain volume due in part to decreased pruning during development. Here we aimed at assessing brain volume early in development to further elucidate previous findings in autism and determine whether this pattern is restricted to idiopathic autism or shared within the autistic phenotype (fragile X syndrome [FXS]). We investigated brain volume in 37 participants, using the fully automated Civet pipeline anatomical magnetic resonance imaging. 3 groups with intellectual deficiency: autism (AUT); its most associated FXS; and its most opposite Williams syndrome (WS) were compared with each other and with normal controls (NC). We report increased total and regional gray and white matter brain volume in AUT and FXS relative to WS and NC. These findings are discussed in light of the possibilities leading for the enlarged brain volume in children with the AUT phenotype. We speculate that this excess suggests reduced regression of neuronal processes “pruning” in cortical and subcortical regions in AUT/FXS, which may be due to a mutation in specific genes involved in pruning and/or a lack of socio-emotional environmental experience during a critical developmental period. En ligne : http://dx.doi.org/10.1016/j.rasd.2011.11.008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=150

---

1 (1 - 2 / 2)