Predictive validity of self-report questionnaires in the assessment of autism spectrum disorders in adults / Bram B. SIZOO in Autism, 19-7 (October 2015)  

Public ISBD [article]  inAutism > 19-7 (October 2015) . - p.842-849 Titre : Predictive validity of self-report questionnaires in the assessment of autism spectrum disorders in adults Type de document : Texte imprimé et/ou numérique Auteurs : Bram B. SIZOO, Auteur ; E. H. HORWITZ, Auteur ; J. P. TEUNISSE, Auteur ; C. C. KAN, Auteur ; Constance T. W. M. VISSERS, Auteur ; E. J. M. FORCEVILLE, Auteur ; A. J. P. VAN VOORST, Auteur ; H. M. GEURTS, Auteur Année de publication : 2015 Article en page(s) : p.842-849 Langues : Anglais (eng) Mots-clés : autism  Autism-Spectrum Quotient  casefinding  RAADS-R-NL  self-report questionnaires Index. décimale : PER Périodiques Résumé : While various screening instruments for autism spectrum disorders are widely used in diagnostic assessments, their psychometric properties have not been simultaneously evaluated in the outpatient setting where these instruments are used most. In this study, we tested the Ritvo Autism Asperger Diagnostic Scale–Revised and two short versions of the Autism-Spectrum Quotient, the AQ-28 and AQ-10, in 210 patients referred for autism spectrum disorder assessment and in 63 controls. Of the 210 patients, 139 received an autism spectrum disorder diagnosis and 71 received another psychiatric diagnosis. The positive predictive values indicate that these tests correctly identified autism spectrum disorder patients in almost 80% of the referred cases. However, the negative predictive values suggest that only half of the referred patients without autism spectrum disorder were correctly identified. The sensitivity and specificity of each of these instruments were much lower than the values reported in the literature. In this study, the sensitivity of the Ritvo Autism Asperger Diagnostic Scale–Revised was the highest (73%), and the Autism-Spectrum Quotient short forms had the highest specificity (70% and 72%). Based on the similar area under the curve values, there is no clear preference for any of the three instruments. None of these instruments have sufficient validity to reliably predict a diagnosis of autism spectrum disorder in outpatient settings. En ligne : http://dx.doi.org/10.1177/1362361315589869 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=269 [article] Predictive validity of self-report questionnaires in the assessment of autism spectrum disorders in adults [Texte imprimé et/ou numérique] / Bram B. SIZOO, Auteur ; E. H. HORWITZ, Auteur ; J. P. TEUNISSE, Auteur ; C. C. KAN, Auteur ; Constance T. W. M. VISSERS, Auteur ; E. J. M. FORCEVILLE, Auteur ; A. J. P. VAN VOORST, Auteur ; H. M. GEURTS, Auteur . - 2015 . - p.842-849. Langues : Anglais (eng) in Autism > 19-7 (October 2015) . - p.842-849 Mots-clés : autism  Autism-Spectrum Quotient  casefinding  RAADS-R-NL  self-report questionnaires Index. décimale : PER Périodiques Résumé : While various screening instruments for autism spectrum disorders are widely used in diagnostic assessments, their psychometric properties have not been simultaneously evaluated in the outpatient setting where these instruments are used most. In this study, we tested the Ritvo Autism Asperger Diagnostic Scale–Revised and two short versions of the Autism-Spectrum Quotient, the AQ-28 and AQ-10, in 210 patients referred for autism spectrum disorder assessment and in 63 controls. Of the 210 patients, 139 received an autism spectrum disorder diagnosis and 71 received another psychiatric diagnosis. The positive predictive values indicate that these tests correctly identified autism spectrum disorder patients in almost 80% of the referred cases. However, the negative predictive values suggest that only half of the referred patients without autism spectrum disorder were correctly identified. The sensitivity and specificity of each of these instruments were much lower than the values reported in the literature. In this study, the sensitivity of the Ritvo Autism Asperger Diagnostic Scale–Revised was the highest (73%), and the Autism-Spectrum Quotient short forms had the highest specificity (70% and 72%). Based on the similar area under the curve values, there is no clear preference for any of the three instruments. None of these instruments have sufficient validity to reliably predict a diagnosis of autism spectrum disorder in outpatient settings. En ligne : http://dx.doi.org/10.1177/1362361315589869 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=269

Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder / Bram B. SIZOO in Autism, 19-4 (May 2015)  

Public ISBD [article]  inAutism > 19-4 (May 2015) . - p.400-408 Titre : Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder Type de document : Texte imprimé et/ou numérique Auteurs : Bram B. SIZOO, Auteur ; Rutger Jan VAN DER GAAG, Auteur ; Wim VAN DEN BRINK, Auteur Article en page(s) : p.400-408 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder and attention deficit/hyperactivity disorder overlap in several ways, raising questions about the nature of this comorbidity. Rommelse et al. published an innovative review of candidate endophenotypes for autism spectrum disorder and attention deficit/hyperactivity disorder in cognitive and brain domains. They found that all the endophenotypic impairments that were reviewed in attention deficit/hyperactivity disorder were also present in autism spectrum disorder, suggesting a continuity model with attention deficit/hyperactivity disorder as “a light form of autism spectrum disorder.” Using existing data, 75 adults with autism spectrum disorder and 53 with attention deficit/hyperactivity disorder were directly compared on autistic symptoms with the autism spectrum quotient, and on the endophenotypic measure of temperament and character, using the Abbreviated (Dutch: Verkorte) Temperament and Character Inventory. Based on the hypothesis that attention deficit/hyperactivity disorder and autism spectrum disorder are disorders on a continuous spectrum, autism spectrum quotient scores and abbreviated Temperament and Character Inventory scores were expected to be different from normal controls in both disorders in a similar direction. In addition, the autism spectrum quotient and abbreviated Temperament and Character Inventory scores were expected to be closely correlated. These conditions applied to only two of the seven Abbreviated Temperament and Character Inventory scales (harm avoidance and self-directedness), suggesting that temperament and character as an endophenotype of autism spectrum disorder and attention deficit/hyperactivity disorder provides only partial support for the continuity hypothesis of autism spectrum disorder and attention deficit/hyperactivity disorder. En ligne : http://dx.doi.org/10.1177/1362361314522352 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=257 [article] Temperament and character as endophenotype in adults with autism spectrum disorders or attention deficit/hyperactivity disorder [Texte imprimé et/ou numérique] / Bram B. SIZOO, Auteur ; Rutger Jan VAN DER GAAG, Auteur ; Wim VAN DEN BRINK, Auteur . - p.400-408. Langues : Anglais (eng) in Autism > 19-4 (May 2015) . - p.400-408 Index. décimale : PER Périodiques Résumé : Autism spectrum disorder and attention deficit/hyperactivity disorder overlap in several ways, raising questions about the nature of this comorbidity. Rommelse et al. published an innovative review of candidate endophenotypes for autism spectrum disorder and attention deficit/hyperactivity disorder in cognitive and brain domains. They found that all the endophenotypic impairments that were reviewed in attention deficit/hyperactivity disorder were also present in autism spectrum disorder, suggesting a continuity model with attention deficit/hyperactivity disorder as “a light form of autism spectrum disorder.” Using existing data, 75 adults with autism spectrum disorder and 53 with attention deficit/hyperactivity disorder were directly compared on autistic symptoms with the autism spectrum quotient, and on the endophenotypic measure of temperament and character, using the Abbreviated (Dutch: Verkorte) Temperament and Character Inventory. Based on the hypothesis that attention deficit/hyperactivity disorder and autism spectrum disorder are disorders on a continuous spectrum, autism spectrum quotient scores and abbreviated Temperament and Character Inventory scores were expected to be different from normal controls in both disorders in a similar direction. In addition, the autism spectrum quotient and abbreviated Temperament and Character Inventory scores were expected to be closely correlated. These conditions applied to only two of the seven Abbreviated Temperament and Character Inventory scales (harm avoidance and self-directedness), suggesting that temperament and character as an endophenotype of autism spectrum disorder and attention deficit/hyperactivity disorder provides only partial support for the continuity hypothesis of autism spectrum disorder and attention deficit/hyperactivity disorder. En ligne : http://dx.doi.org/10.1177/1362361314522352 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=257

Using the Autism-Spectrum Quotient to Discriminate Autism Spectrum Disorder from ADHD in Adult Patients With and Without Comorbid Substance Use Disorder / Bram B. SIZOO in Journal of Autism and Developmental Disorders, 39-9 (September 2009)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 39-9 (September 2009) . - p.1291-1297 Titre : Using the Autism-Spectrum Quotient to Discriminate Autism Spectrum Disorder from ADHD in Adult Patients With and Without Comorbid Substance Use Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Bram B. SIZOO, Auteur ; Rutger Jan VAN DER GAAG, Auteur ; Wim VAN DEN BRINK, Auteur ; Marielle GORISSEN-VAN EENIGE, Auteur ; Maarten W. KOETER, Auteur ; Patricia J. M. VAN WIJNGAARDEN-CREMERS, Auteur Année de publication : 2009 Article en page(s) : p.1291-1297 Note générale : Open Access Langues : Anglais (eng) Mots-clés : Autism-spectrum-disorder ADHD Substance-use-disorder Autism-spectrum-quotient Index. décimale : PER Périodiques Résumé : It is unknown whether the Autism-spectrum quotient (AQ) can discriminate between Autism Spectrum Disorder (ASD) and Attention Deficit and Hyperactivity Disorder (ADHD) with or without comorbid Substance Use Disorder (SUD). ANOVA’s were used to analyse the mean AQ (sub)scores of 129 adults with ASD or ADHD. We applied receiver operating characteristic (ROC) computations to assess discriminant power. All but one of the mean AQ (sub)scores were significantly higher for adults with ASD compared to those with ADHD. The SUD status in general was not significantly associated with AQ (sub)scores. On the Social Skills subscale patients with ASD and comorbid SUD showed less impairment than those without SUD. The cut-off score 26 yielded 73% correct classifications. The clinical use of the AQ in differentiating between ASD and ADHD is limited. En ligne : http://dx.doi.org/10.1007/s10803-009-0743-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=814 [article] Using the Autism-Spectrum Quotient to Discriminate Autism Spectrum Disorder from ADHD in Adult Patients With and Without Comorbid Substance Use Disorder [Texte imprimé et/ou numérique] / Bram B. SIZOO, Auteur ; Rutger Jan VAN DER GAAG, Auteur ; Wim VAN DEN BRINK, Auteur ; Marielle GORISSEN-VAN EENIGE, Auteur ; Maarten W. KOETER, Auteur ; Patricia J. M. VAN WIJNGAARDEN-CREMERS, Auteur . - 2009 . - p.1291-1297. Open Access Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 39-9 (September 2009) . - p.1291-1297 Mots-clés : Autism-spectrum-disorder ADHD Substance-use-disorder Autism-spectrum-quotient Index. décimale : PER Périodiques Résumé : It is unknown whether the Autism-spectrum quotient (AQ) can discriminate between Autism Spectrum Disorder (ASD) and Attention Deficit and Hyperactivity Disorder (ADHD) with or without comorbid Substance Use Disorder (SUD). ANOVA’s were used to analyse the mean AQ (sub)scores of 129 adults with ASD or ADHD. We applied receiver operating characteristic (ROC) computations to assess discriminant power. All but one of the mean AQ (sub)scores were significantly higher for adults with ASD compared to those with ADHD. The SUD status in general was not significantly associated with AQ (sub)scores. On the Social Skills subscale patients with ASD and comorbid SUD showed less impairment than those without SUD. The cut-off score 26 yielded 73% correct classifications. The clinical use of the AQ in differentiating between ASD and ADHD is limited. En ligne : http://dx.doi.org/10.1007/s10803-009-0743-2 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=814

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