[article]
| Titre : |
Melatonin Versus Placebo in Children with Autism Spectrum Conditions and Severe Sleep Problems Not Amenable to Behaviour Management Strategies: A Randomised Controlled Crossover Trial |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Barry WRIGHT, Auteur ; David SIMS, Auteur ; Siobhan SMART, Auteur ; Ahmed ALWAZEER, Auteur ; Ben ALDERSON-DAY, Auteur ; Victoria ALLGAR, Auteur ; Clare WHITTON, Auteur ; Heather TOMLINSON, Auteur ; Sophie D. BENNETT, Auteur ; Jenni JARDINE, Auteur ; Nicola MCAFFREY, Auteur ; Charlotte LEYLAND, Auteur ; Christine JAKEMAN, Auteur ; Jeremy N.V. MILES, Auteur |
| Année de publication : |
2011 |
| Article en page(s) : |
p.175-184 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Melatonin Sleep Autism spectrum disorders Dysomnia |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Twenty-two children with autism spectrum disorders who had not responded to supported behaviour management strategies for severe dysomnias entered a double blind, randomised, controlled crossover trial involving 3 months of placebo versus 3 months of melatonin to a maximum dose of 10 mg. 17 children completed the study. There were no significant differences between sleep variables at baseline. Melatonin significantly improved sleep latency (by an average of 47 min) and total sleep (by an average of 52 min) compared to placebo, but not number of night wakenings. The side effect profile was low and not significantly different between the two arms. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-010-1036-5 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=117 |
in Journal of Autism and Developmental Disorders > 41-2 (February 2011) . - p.175-184
[article] Melatonin Versus Placebo in Children with Autism Spectrum Conditions and Severe Sleep Problems Not Amenable to Behaviour Management Strategies: A Randomised Controlled Crossover Trial [Texte imprimé et/ou numérique] / Barry WRIGHT, Auteur ; David SIMS, Auteur ; Siobhan SMART, Auteur ; Ahmed ALWAZEER, Auteur ; Ben ALDERSON-DAY, Auteur ; Victoria ALLGAR, Auteur ; Clare WHITTON, Auteur ; Heather TOMLINSON, Auteur ; Sophie D. BENNETT, Auteur ; Jenni JARDINE, Auteur ; Nicola MCAFFREY, Auteur ; Charlotte LEYLAND, Auteur ; Christine JAKEMAN, Auteur ; Jeremy N.V. MILES, Auteur . - 2011 . - p.175-184. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 41-2 (February 2011) . - p.175-184
| Mots-clés : |
Melatonin Sleep Autism spectrum disorders Dysomnia |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Twenty-two children with autism spectrum disorders who had not responded to supported behaviour management strategies for severe dysomnias entered a double blind, randomised, controlled crossover trial involving 3 months of placebo versus 3 months of melatonin to a maximum dose of 10 mg. 17 children completed the study. There were no significant differences between sleep variables at baseline. Melatonin significantly improved sleep latency (by an average of 47 min) and total sleep (by an average of 52 min) compared to placebo, but not number of night wakenings. The side effect profile was low and not significantly different between the two arms. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-010-1036-5 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=117 |
|
Melatonin Versus Placebo in Children with Autism Spectrum Conditions and Severe Sleep Problems Not Amenable to Behaviour Management Strategies: A Randomised Controlled Crossover Trial in Journal of Autism and Developmental Disorders, 41-2 (February 2011)
