1186 recherche sur le mot-clé 'Autism spectrum disorders'

Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study / Sebastian LUNDSTROM in Journal of Child Psychology and Psychiatry, 56-6 (June 2015)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 56-6 (June 2015) . - p.702-710 Titre : Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study Type de document : Texte imprimé et/ou numérique Auteurs : Sebastian LUNDSTROM, Auteur ; Abraham REICHENBERG, Auteur ; Jonas MELKE, Auteur ; Maria RASTAM, Auteur ; Nora KEREKES, Auteur ; Paul LICHTENSTEIN, Auteur ; Christopher GILLBERG, Auteur ; Henrik ANCKARSATER, Auteur Article en page(s) : p.702-710 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  comorbidity  genetics  twins Index. décimale : PER Périodiques Résumé : Background Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ASD without coexisting disorders is rare. The present study aims to examine the range of coexisting disorders in ASD in a genetically informative cohort. Methods Parents of all Swedish 9-year-old twins born between 1992 and 2001 (n = 19,130) underwent a telephone interview designed to screen for child psychiatric disorders, including ASD. To ensure full coverage of child psychiatric disorders, data were also retrieved from population-based health registers. We investigated the coexistence of eight psychiatric disorders known to coexist with ASDs in probands and their co-twins. Results Half of the individuals with ASDs (50.3%) had four or more coexisting disorders and only 4% did not have any concomitant disorder. The ‘healthy co-twin’ in ASD discordant monozygotic twin pairs was very often (79% of boys and 50% of girls) affected by at least one non-ASD disorder. The corresponding figures for ASD discordant dizygotic twin pairs were significantly lower (46% of males and 30% of females). Conclusions Detailed phenotypic descriptions including symptoms of problems associated with a wide range of child psychiatric disorders may aid in unraveling the genetic architecture of ASD and should guide the development of intervention strategies addressing each problem type specifically. En ligne : http://dx.doi.org/10.1111/jcpp.12329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 [article] Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study [Texte imprimé et/ou numérique] / Sebastian LUNDSTROM, Auteur ; Abraham REICHENBERG, Auteur ; Jonas MELKE, Auteur ; Maria RASTAM, Auteur ; Nora KEREKES, Auteur ; Paul LICHTENSTEIN, Auteur ; Christopher GILLBERG, Auteur ; Henrik ANCKARSATER, Auteur . - p.702-710. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 56-6 (June 2015) . - p.702-710 Mots-clés : Autism spectrum disorders  comorbidity  genetics  twins Index. décimale : PER Périodiques Résumé : Background Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ASD without coexisting disorders is rare. The present study aims to examine the range of coexisting disorders in ASD in a genetically informative cohort. Methods Parents of all Swedish 9-year-old twins born between 1992 and 2001 (n = 19,130) underwent a telephone interview designed to screen for child psychiatric disorders, including ASD. To ensure full coverage of child psychiatric disorders, data were also retrieved from population-based health registers. We investigated the coexistence of eight psychiatric disorders known to coexist with ASDs in probands and their co-twins. Results Half of the individuals with ASDs (50.3%) had four or more coexisting disorders and only 4% did not have any concomitant disorder. The ‘healthy co-twin’ in ASD discordant monozygotic twin pairs was very often (79% of boys and 50% of girls) affected by at least one non-ASD disorder. The corresponding figures for ASD discordant dizygotic twin pairs were significantly lower (46% of males and 30% of females). Conclusions Detailed phenotypic descriptions including symptoms of problems associated with a wide range of child psychiatric disorders may aid in unraveling the genetic architecture of ASD and should guide the development of intervention strategies addressing each problem type specifically. En ligne : http://dx.doi.org/10.1111/jcpp.12329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260

Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood / A. J. HINNEBUSCH in Journal of Autism and Developmental Disorders, 47-12 (December 2017)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3967-3982 Titre : Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood Type de document : Texte imprimé et/ou numérique Auteurs : A. J. HINNEBUSCH, Auteur ; L. E. MILLER, Auteur ; Deborah A. FEIN, Auteur Année de publication : 2017 Article en page(s) : p.3967-3982 Langues : Anglais (eng) Mots-clés : Autism severity  Autism spectrum disorders  Developmental growth  Diagnostic stability  Low mental age Index. décimale : PER Périodiques Résumé : Some children with autism spectrum disorders (ASDs) exhibit low mental age (Low-MA; i.e., cognitive functioning below 12 months). We examined diagnosis, symptom severity, and development in children with ASD-low MA (n = 25), autistic disorder (n = 111), and PDD-NOS (n = 82) at ages two and four. We predicted that some ASD-low MA children would demonstrate just intellectual impairment and not autism symptoms on follow-up, with social deficits at age two attributable to global delays. Instead, most ASD-low MA children (96%) had an ASD at follow-up, compared to children initially diagnosed with autistic disorder (86.5%) or PDD-NOS (73.2%). They showed the least developmental progress and highest symptom severity. Results support diagnosing ASDs in children functioning below a 12-month level. En ligne : http://dx.doi.org/10.1007/s10803-017-3278-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326 [article] Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood [Texte imprimé et/ou numérique] / A. J. HINNEBUSCH, Auteur ; L. E. MILLER, Auteur ; Deborah A. FEIN, Auteur . - 2017 . - p.3967-3982. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3967-3982 Mots-clés : Autism severity  Autism spectrum disorders  Developmental growth  Diagnostic stability  Low mental age Index. décimale : PER Périodiques Résumé : Some children with autism spectrum disorders (ASDs) exhibit low mental age (Low-MA; i.e., cognitive functioning below 12 months). We examined diagnosis, symptom severity, and development in children with ASD-low MA (n = 25), autistic disorder (n = 111), and PDD-NOS (n = 82) at ages two and four. We predicted that some ASD-low MA children would demonstrate just intellectual impairment and not autism symptoms on follow-up, with social deficits at age two attributable to global delays. Instead, most ASD-low MA children (96%) had an ASD at follow-up, compared to children initially diagnosed with autistic disorder (86.5%) or PDD-NOS (73.2%). They showed the least developmental progress and highest symptom severity. Results support diagnosing ASDs in children functioning below a 12-month level. En ligne : http://dx.doi.org/10.1007/s10803-017-3278-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326

Autism Spectrum Disorders and Self-reports: Testing Validity and Reliability Using the NEO-PI-R / Eva HESSELMARK in Journal of Autism and Developmental Disorders, 45-5 (May 2015)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1156-1166 Titre : Autism Spectrum Disorders and Self-reports: Testing Validity and Reliability Using the NEO-PI-R Type de document : Texte imprimé et/ou numérique Auteurs : Eva HESSELMARK, Auteur ; Jonna M. ERIKSSON, Auteur ; Joakim WESTERLUND, Auteur ; Susanne BEJEROT, Auteur Article en page(s) : p.1156-1166 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Self report  Psychometrics  Validation  Personality tests Index. décimale : PER Périodiques Résumé : Although self-reported measures are frequently used to assess adults with autism spectrum disorders (ASD), the validity of self-reports is under-researched in ASD. The core symptoms of ASD may negatively affect the psychometric properties of self-reported measures. The aim of the present study was to test the validity and reliability of self-reported data using the NEO personality inventory-revised (NEO-PI-R). Forty-eight adults with ASD and 53 controls completed the NEO-PI-R and a psychiatric interview. Results indicate satisfactory internal consistency of the NEO-PI-R, a satisfactory factor structure, predicted correlations with clinician ratings in the ASD group, and predicted differences in personality between the ASD group and controls. In conclusion, the present results support the use of self-reported measures when assessing adults with ASD . En ligne : http://dx.doi.org/10.1007/s10803-014-2275-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 [article] Autism Spectrum Disorders and Self-reports: Testing Validity and Reliability Using the NEO-PI-R [Texte imprimé et/ou numérique] / Eva HESSELMARK, Auteur ; Jonna M. ERIKSSON, Auteur ; Joakim WESTERLUND, Auteur ; Susanne BEJEROT, Auteur . - p.1156-1166. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1156-1166 Mots-clés : Autism spectrum disorders  Self report  Psychometrics  Validation  Personality tests Index. décimale : PER Périodiques Résumé : Although self-reported measures are frequently used to assess adults with autism spectrum disorders (ASD), the validity of self-reports is under-researched in ASD. The core symptoms of ASD may negatively affect the psychometric properties of self-reported measures. The aim of the present study was to test the validity and reliability of self-reported data using the NEO personality inventory-revised (NEO-PI-R). Forty-eight adults with ASD and 53 controls completed the NEO-PI-R and a psychiatric interview. Results indicate satisfactory internal consistency of the NEO-PI-R, a satisfactory factor structure, predicted correlations with clinician ratings in the ASD group, and predicted differences in personality between the ASD group and controls. In conclusion, the present results support the use of self-reported measures when assessing adults with ASD . En ligne : http://dx.doi.org/10.1007/s10803-014-2275-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259

Autism spectrum disorders and the amplitude of auditory brainstem response wave I / Mariline SANTOS in Autism Research, 10-7 (July 2017)  

Public ISBD [article]  inAutism Research > 10-7 (July 2017) . - p.1300-1305 Titre : Autism spectrum disorders and the amplitude of auditory brainstem response wave I Type de document : Texte imprimé et/ou numérique Auteurs : Mariline SANTOS, Auteur ; Cristina MARQUES, Auteur ; Ana NÓBREGA PINTO, Auteur ; Raquel FERNANDES, Auteur ; Miguel Bebiano COUTINHO, Auteur ; Cecília ALMEIDA E SOUSA, Auteur Article en page(s) : p.1300-1305 Langues : Anglais (eng) Mots-clés : auditory brainstem response  autism spectrum disorders  hearing Index. décimale : PER Périodiques Résumé : To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case–control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I–III, III–IV, and I–V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case–control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. En ligne : http://dx.doi.org/10.1002/aur.1771 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310 [article] Autism spectrum disorders and the amplitude of auditory brainstem response wave I [Texte imprimé et/ou numérique] / Mariline SANTOS, Auteur ; Cristina MARQUES, Auteur ; Ana NÓBREGA PINTO, Auteur ; Raquel FERNANDES, Auteur ; Miguel Bebiano COUTINHO, Auteur ; Cecília ALMEIDA E SOUSA, Auteur . - p.1300-1305. Langues : Anglais (eng) in Autism Research > 10-7 (July 2017) . - p.1300-1305 Mots-clés : auditory brainstem response  autism spectrum disorders  hearing Index. décimale : PER Périodiques Résumé : To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case–control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I–III, III–IV, and I–V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case–control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. En ligne : http://dx.doi.org/10.1002/aur.1771 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310

Autism spectrum disorders: Methodological considerations for Early Intensive Behavioral Interventions / Johnny L. MATSON in Research in Autism Spectrum Disorders, 7-7 (July 2013)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 7-7 (July 2013) . - p.809-814 Titre : Autism spectrum disorders: Methodological considerations for Early Intensive Behavioral Interventions Type de document : Texte imprimé et/ou numérique Auteurs : Johnny L. MATSON, Auteur ; Jina JANG, Auteur Article en page(s) : p.809-814 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders  Early intervention  Methodology Index. décimale : PER Périodiques Résumé : Early Intensive Behavioral Intervention (EIBI) has become a cornerstone of early intervention for young children with autism spectrum disorders (ASDs). As this field has matured, the emphasis will need to shift from does it work to more specific and tailored research topics. Increasing compatibility across studies will be critical. Establishing more rigorous methods of group assignment and more systematic and detailed descriptions of participants, and developing more up-to-date criteria and methods of diagnosis will be needed. Also, providing more systematic and detailed descriptions of treatment and more emphasis on staff training and treatment integrity will be required. How methodology can be improved serves as the primary focus of the paper. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.01.006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=200 [article] Autism spectrum disorders: Methodological considerations for Early Intensive Behavioral Interventions [Texte imprimé et/ou numérique] / Johnny L. MATSON, Auteur ; Jina JANG, Auteur . - p.809-814. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 7-7 (July 2013) . - p.809-814 Mots-clés : Autism spectrum disorders  Early intervention  Methodology Index. décimale : PER Périodiques Résumé : Early Intensive Behavioral Intervention (EIBI) has become a cornerstone of early intervention for young children with autism spectrum disorders (ASDs). As this field has matured, the emphasis will need to shift from does it work to more specific and tailored research topics. Increasing compatibility across studies will be critical. Establishing more rigorous methods of group assignment and more systematic and detailed descriptions of participants, and developing more up-to-date criteria and methods of diagnosis will be needed. Also, providing more systematic and detailed descriptions of treatment and more emphasis on staff training and treatment integrity will be required. How methodology can be improved serves as the primary focus of the paper. En ligne : http://dx.doi.org/10.1016/j.rasd.2013.01.006 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=200

Autism spectrum disorders: Neuroimaging findings from systematic reviews / Emmanuel Peng Kiat PUA in Research in Autism Spectrum Disorders, 34 (February 2017)  

Permalink

Altered Pre-reflective Sense of Agency in Autism Spectrum Disorders as Revealed by Reduced Intentional Binding / Marco SPERDUTI in Journal of Autism and Developmental Disorders, 44-2 (February 2014)  

Permalink

Brief Report: Macrocephaly Phenotype and Psychiatric Comorbidity in a Clinical Sample of Mexican Children and Adolescents with Autism Spectrum Disorders / Lilia ALBORES-GALLO in Journal of Autism and Developmental Disorders, 47-9 (September 2017)  

Permalink

Cross-Sectional Evidence for a Decrease in Cognitive Function With Age in Children With Autism Spectrum Disorders? / Petra Suzanne BARNEVELD in Autism Research, 7-5 (October 2014)  

Permalink

Diagnostic Yield of Chromosomal Microarray Analysis in a Cohort of Patients with Autism Spectrum Disorders from a Highly Consanguineous Population / Watfa AL-MAMARI in Journal of Autism and Developmental Disorders, 45-8 (August 2015)  

Permalink