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Faire une suggestionAutism spectrum disorders and coexisting disorders in a nationwide Swedish twin study / Sebastian LUNDSTROM in Journal of Child Psychology and Psychiatry, 56-6 (June 2015)
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Titre : Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study Type de document : texte imprimé Auteurs : Sebastian LUNDSTROM, Auteur ; Abraham REICHENBERG, Auteur ; Jonas MELKE, Auteur ; Maria RASTAM, Auteur ; Nora KEREKES, Auteur ; Paul LICHTENSTEIN, Auteur ; Christopher GILLBERG, Auteur ; Henrik ANCKARSATER, Auteur Article en page(s) : p.702-710 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders comorbidity genetics twins Index. décimale : PER Périodiques Résumé : Background Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ASD without coexisting disorders is rare. The present study aims to examine the range of coexisting disorders in ASD in a genetically informative cohort. Methods Parents of all Swedish 9-year-old twins born between 1992 and 2001 (n = 19,130) underwent a telephone interview designed to screen for child psychiatric disorders, including ASD. To ensure full coverage of child psychiatric disorders, data were also retrieved from population-based health registers. We investigated the coexistence of eight psychiatric disorders known to coexist with ASDs in probands and their co-twins. Results Half of the individuals with ASDs (50.3%) had four or more coexisting disorders and only 4% did not have any concomitant disorder. The ‘healthy co-twin’ in ASD discordant monozygotic twin pairs was very often (79% of boys and 50% of girls) affected by at least one non-ASD disorder. The corresponding figures for ASD discordant dizygotic twin pairs were significantly lower (46% of males and 30% of females). Conclusions Detailed phenotypic descriptions including symptoms of problems associated with a wide range of child psychiatric disorders may aid in unraveling the genetic architecture of ASD and should guide the development of intervention strategies addressing each problem type specifically. En ligne : http://dx.doi.org/10.1111/jcpp.12329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260
in Journal of Child Psychology and Psychiatry > 56-6 (June 2015) . - p.702-710[article] Autism spectrum disorders and coexisting disorders in a nationwide Swedish twin study [texte imprimé] / Sebastian LUNDSTROM, Auteur ; Abraham REICHENBERG, Auteur ; Jonas MELKE, Auteur ; Maria RASTAM, Auteur ; Nora KEREKES, Auteur ; Paul LICHTENSTEIN, Auteur ; Christopher GILLBERG, Auteur ; Henrik ANCKARSATER, Auteur . - p.702-710.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 56-6 (June 2015) . - p.702-710
Mots-clés : Autism spectrum disorders comorbidity genetics twins Index. décimale : PER Périodiques Résumé : Background Evidence from twin and molecular genetic studies is accumulating that Autism Spectrum Disorder (ASD) shares substantial etiological factors with other disorders. This is mirrored in clinical practice where ASD without coexisting disorders is rare. The present study aims to examine the range of coexisting disorders in ASD in a genetically informative cohort. Methods Parents of all Swedish 9-year-old twins born between 1992 and 2001 (n = 19,130) underwent a telephone interview designed to screen for child psychiatric disorders, including ASD. To ensure full coverage of child psychiatric disorders, data were also retrieved from population-based health registers. We investigated the coexistence of eight psychiatric disorders known to coexist with ASDs in probands and their co-twins. Results Half of the individuals with ASDs (50.3%) had four or more coexisting disorders and only 4% did not have any concomitant disorder. The ‘healthy co-twin’ in ASD discordant monozygotic twin pairs was very often (79% of boys and 50% of girls) affected by at least one non-ASD disorder. The corresponding figures for ASD discordant dizygotic twin pairs were significantly lower (46% of males and 30% of females). Conclusions Detailed phenotypic descriptions including symptoms of problems associated with a wide range of child psychiatric disorders may aid in unraveling the genetic architecture of ASD and should guide the development of intervention strategies addressing each problem type specifically. En ligne : http://dx.doi.org/10.1111/jcpp.12329 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=260 Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood / A. J. HINNEBUSCH in Journal of Autism and Developmental Disorders, 47-12 (December 2017)
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Titre : Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood Type de document : texte imprimé Auteurs : A. J. HINNEBUSCH, Auteur ; L. E. MILLER, Auteur ; Deborah A. FEIN, Auteur Année de publication : 2017 Article en page(s) : p.3967-3982 Langues : Anglais (eng) Mots-clés : Autism severity Autism spectrum disorders Developmental growth Diagnostic stability Low mental age Index. décimale : PER Périodiques Résumé : Some children with autism spectrum disorders (ASDs) exhibit low mental age (Low-MA; i.e., cognitive functioning below 12 months). We examined diagnosis, symptom severity, and development in children with ASD-low MA (n = 25), autistic disorder (n = 111), and PDD-NOS (n = 82) at ages two and four. We predicted that some ASD-low MA children would demonstrate just intellectual impairment and not autism symptoms on follow-up, with social deficits at age two attributable to global delays. Instead, most ASD-low MA children (96%) had an ASD at follow-up, compared to children initially diagnosed with autistic disorder (86.5%) or PDD-NOS (73.2%). They showed the least developmental progress and highest symptom severity. Results support diagnosing ASDs in children functioning below a 12-month level. En ligne : http://dx.doi.org/10.1007/s10803-017-3278-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326
in Journal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3967-3982[article] Autism Spectrum Disorders and Low Mental Age: Diagnostic Stability and Developmental Outcomes in Early Childhood [texte imprimé] / A. J. HINNEBUSCH, Auteur ; L. E. MILLER, Auteur ; Deborah A. FEIN, Auteur . - 2017 . - p.3967-3982.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-12 (December 2017) . - p.3967-3982
Mots-clés : Autism severity Autism spectrum disorders Developmental growth Diagnostic stability Low mental age Index. décimale : PER Périodiques Résumé : Some children with autism spectrum disorders (ASDs) exhibit low mental age (Low-MA; i.e., cognitive functioning below 12 months). We examined diagnosis, symptom severity, and development in children with ASD-low MA (n = 25), autistic disorder (n = 111), and PDD-NOS (n = 82) at ages two and four. We predicted that some ASD-low MA children would demonstrate just intellectual impairment and not autism symptoms on follow-up, with social deficits at age two attributable to global delays. Instead, most ASD-low MA children (96%) had an ASD at follow-up, compared to children initially diagnosed with autistic disorder (86.5%) or PDD-NOS (73.2%). They showed the least developmental progress and highest symptom severity. Results support diagnosing ASDs in children functioning below a 12-month level. En ligne : http://dx.doi.org/10.1007/s10803-017-3278-y Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=326 Autism Spectrum Disorders and Self-reports: Testing Validity and Reliability Using the NEO-PI-R / Eva HESSELMARK in Journal of Autism and Developmental Disorders, 45-5 (May 2015)
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Titre : Autism Spectrum Disorders and Self-reports: Testing Validity and Reliability Using the NEO-PI-R Type de document : texte imprimé Auteurs : Eva HESSELMARK, Auteur ; Jonna M. ERIKSSON, Auteur ; Joakim WESTERLUND, Auteur ; Susanne BEJEROT, Auteur Article en page(s) : p.1156-1166 Langues : Anglais (eng) Mots-clés : Autism spectrum disorders Self report Psychometrics Validation Personality tests Index. décimale : PER Périodiques Résumé : Although self-reported measures are frequently used to assess adults with autism spectrum disorders (ASD), the validity of self-reports is under-researched in ASD. The core symptoms of ASD may negatively affect the psychometric properties of self-reported measures. The aim of the present study was to test the validity and reliability of self-reported data using the NEO personality inventory-revised (NEO-PI-R). Forty-eight adults with ASD and 53 controls completed the NEO-PI-R and a psychiatric interview. Results indicate satisfactory internal consistency of the NEO-PI-R, a satisfactory factor structure, predicted correlations with clinician ratings in the ASD group, and predicted differences in personality between the ASD group and controls. In conclusion, the present results support the use of self-reported measures when assessing adults with ASD . En ligne : http://dx.doi.org/10.1007/s10803-014-2275-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259
in Journal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1156-1166[article] Autism Spectrum Disorders and Self-reports: Testing Validity and Reliability Using the NEO-PI-R [texte imprimé] / Eva HESSELMARK, Auteur ; Jonna M. ERIKSSON, Auteur ; Joakim WESTERLUND, Auteur ; Susanne BEJEROT, Auteur . - p.1156-1166.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 45-5 (May 2015) . - p.1156-1166
Mots-clés : Autism spectrum disorders Self report Psychometrics Validation Personality tests Index. décimale : PER Périodiques Résumé : Although self-reported measures are frequently used to assess adults with autism spectrum disorders (ASD), the validity of self-reports is under-researched in ASD. The core symptoms of ASD may negatively affect the psychometric properties of self-reported measures. The aim of the present study was to test the validity and reliability of self-reported data using the NEO personality inventory-revised (NEO-PI-R). Forty-eight adults with ASD and 53 controls completed the NEO-PI-R and a psychiatric interview. Results indicate satisfactory internal consistency of the NEO-PI-R, a satisfactory factor structure, predicted correlations with clinician ratings in the ASD group, and predicted differences in personality between the ASD group and controls. In conclusion, the present results support the use of self-reported measures when assessing adults with ASD . En ligne : http://dx.doi.org/10.1007/s10803-014-2275-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=259 Autism spectrum disorders and the amplitude of auditory brainstem response wave I / Mariline SANTOS in Autism Research, 10-7 (July 2017)
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Titre : Autism spectrum disorders and the amplitude of auditory brainstem response wave I Type de document : texte imprimé Auteurs : Mariline SANTOS, Auteur ; Cristina MARQUES, Auteur ; Ana NÓBREGA PINTO, Auteur ; Raquel FERNANDES, Auteur ; Miguel Bebiano COUTINHO, Auteur ; CecÃlia ALMEIDA E SOUSA, Auteur Article en page(s) : p.1300-1305 Langues : Anglais (eng) Mots-clés : auditory brainstem response autism spectrum disorders hearing Index. décimale : PER Périodiques Résumé : To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case–control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I–III, III–IV, and I–V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case–control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. En ligne : http://dx.doi.org/10.1002/aur.1771 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310
in Autism Research > 10-7 (July 2017) . - p.1300-1305[article] Autism spectrum disorders and the amplitude of auditory brainstem response wave I [texte imprimé] / Mariline SANTOS, Auteur ; Cristina MARQUES, Auteur ; Ana NÓBREGA PINTO, Auteur ; Raquel FERNANDES, Auteur ; Miguel Bebiano COUTINHO, Auteur ; CecÃlia ALMEIDA E SOUSA, Auteur . - p.1300-1305.
Langues : Anglais (eng)
in Autism Research > 10-7 (July 2017) . - p.1300-1305
Mots-clés : auditory brainstem response autism spectrum disorders hearing Index. décimale : PER Périodiques Résumé : To determine whether children with autism spectrum disorders (ASDs) have an increased number of wave I abnormal amplitudes in auditory brainstem responses (ABRs) than age- and sex-matched typically developing children. This analytical case–control study compared patients with ASDs between the ages of 2 and 6 years and children who had a language delay not associated with any other pathology. Amplitudes of ABR waves I and V; absolute latencies (ALs) of waves I, III, and V; and interpeak latencies (IPLs) I–III, III–IV, and I–V at 90 dB were compared between ASD patients and normally developing children. The study enrolled 40 children with documented ASDs and 40 age- and sex-matched control subjects. Analyses of the ABR showed that children with ASDs exhibited higher amplitudes of wave 1 than wave V (35%) more frequently than the control group (10%), and this difference between groups reached statistical significance by Chi-squared analysis. There were no significant differences in ALs and IPLs between ASD children and matched controls. To the best of our knowledge, this is the first case–control study testing the amplitudes of ABR wave I in ASD children. The reported results suggest a potential for the use of ABR recordings in children, not only for the clinical assessment of hearing status, but also for the possibility of using amplitude of ABR wave I as an early marker of ASDs allowing earlier diagnosis and intervention. En ligne : http://dx.doi.org/10.1002/aur.1771 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=310 Autism Spectrum Disorders Discourse on Social Media Platforms: A Topic Modeling Study of Reddit Posts / Seraphina FONG in Autism Research, 18-8 (August 2025)
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Titre : Autism Spectrum Disorders Discourse on Social Media Platforms: A Topic Modeling Study of Reddit Posts Type de document : texte imprimé Auteurs : Seraphina FONG, Auteur ; Alessandro CAROLLO, Auteur ; Giacomo VIVANTI, Auteur ; Daniel S. MESSINGER, Auteur ; Dagmara DIMITRIOU, Auteur ; Gianluca ESPOSITO, Auteur Article en page(s) : p.1608-1619 Langues : Anglais (eng) Mots-clés : autism autism spectrum disorders BERTopic natural language processing neurodevelopmental conditions social media social networking sites topic modeling Index. décimale : PER Périodiques Résumé : ABSTRACT Social media platforms play a crucial role in shaping public perceptions of neurodevelopmental conditions, such as autism spectrum disorders, by providing spaces for community interaction and content sharing. These platforms hold the potential to foster connections and support among autistic individuals while offering valuable insights into their personal experiences and diverse perspectives. However, knowledge is limited on autism-related content shared within Reddit, one of the most prominent social media outlets. In this study, we aimed to examine discussions and narratives shared on Reddit about autism, with the dual objectives of identifying the main topics of discussion and exploring the lived experiences of autistic individuals. To achieve this, we utilized state-of-the-art natural language processing techniques to perform a topic modeling analysis on 740,042 autism-related posts collected from Reddit. Converging themes emerged when comparing the largest and most general subreddit in the dataset (r/autism) with 15 additional autism-related subreddits. The most prominent topics of discussion included challenges in social relationships, behaviors such as stimming, and sensory sensitivities. Additional themes highlighted specific emotional experiences and practical concerns, such as managing a diagnosis, navigating intervention options, and coping with daily life. These findings were organized and discussed in relation to social communication differences and restricted, repetitive behaviors, which are frequently highlighted in discussions about autism. At the same time, we acknowledge the perspective of autistic communities, which view these traits as differences rather than deficits, with many challenges arising from societal expectations and the pressure to mask neurodivergent traits. Together, the results provide a comprehensive overview of the most common topics discussed within autism-related social media content and offer valuable insights into the lived experiences and motivations for social media engagement among autistic individuals. En ligne : https://doi.org/10.1002/aur.70066 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=566
in Autism Research > 18-8 (August 2025) . - p.1608-1619[article] Autism Spectrum Disorders Discourse on Social Media Platforms: A Topic Modeling Study of Reddit Posts [texte imprimé] / Seraphina FONG, Auteur ; Alessandro CAROLLO, Auteur ; Giacomo VIVANTI, Auteur ; Daniel S. MESSINGER, Auteur ; Dagmara DIMITRIOU, Auteur ; Gianluca ESPOSITO, Auteur . - p.1608-1619.
Langues : Anglais (eng)
in Autism Research > 18-8 (August 2025) . - p.1608-1619
Mots-clés : autism autism spectrum disorders BERTopic natural language processing neurodevelopmental conditions social media social networking sites topic modeling Index. décimale : PER Périodiques Résumé : ABSTRACT Social media platforms play a crucial role in shaping public perceptions of neurodevelopmental conditions, such as autism spectrum disorders, by providing spaces for community interaction and content sharing. These platforms hold the potential to foster connections and support among autistic individuals while offering valuable insights into their personal experiences and diverse perspectives. However, knowledge is limited on autism-related content shared within Reddit, one of the most prominent social media outlets. In this study, we aimed to examine discussions and narratives shared on Reddit about autism, with the dual objectives of identifying the main topics of discussion and exploring the lived experiences of autistic individuals. To achieve this, we utilized state-of-the-art natural language processing techniques to perform a topic modeling analysis on 740,042 autism-related posts collected from Reddit. Converging themes emerged when comparing the largest and most general subreddit in the dataset (r/autism) with 15 additional autism-related subreddits. The most prominent topics of discussion included challenges in social relationships, behaviors such as stimming, and sensory sensitivities. Additional themes highlighted specific emotional experiences and practical concerns, such as managing a diagnosis, navigating intervention options, and coping with daily life. These findings were organized and discussed in relation to social communication differences and restricted, repetitive behaviors, which are frequently highlighted in discussions about autism. At the same time, we acknowledge the perspective of autistic communities, which view these traits as differences rather than deficits, with many challenges arising from societal expectations and the pressure to mask neurodivergent traits. Together, the results provide a comprehensive overview of the most common topics discussed within autism-related social media content and offer valuable insights into the lived experiences and motivations for social media engagement among autistic individuals. En ligne : https://doi.org/10.1002/aur.70066 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=566 Autism spectrum disorders: Methodological considerations for Early Intensive Behavioral Interventions / Johnny L. MATSON in Research in Autism Spectrum Disorders, 7-7 (July 2013)
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PermalinkAutism spectrum disorders: Neuroimaging findings from systematic reviews / Emmanuel Peng Kiat PUA in Research in Autism Spectrum Disorders, 34 (February 2017)
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PermalinkAltered Pre-reflective Sense of Agency in Autism Spectrum Disorders as Revealed by Reduced Intentional Binding / Marco SPERDUTI in Journal of Autism and Developmental Disorders, 44-2 (February 2014)
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PermalinkBrief Report: Macrocephaly Phenotype and Psychiatric Comorbidity in a Clinical Sample of Mexican Children and Adolescents with Autism Spectrum Disorders / Lilia ALBORES-GALLO in Journal of Autism and Developmental Disorders, 47-9 (September 2017)
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PermalinkCross-Sectional Evidence for a Decrease in Cognitive Function With Age in Children With Autism Spectrum Disorders? / Petra Suzanne BARNEVELD in Autism Research, 7-5 (October 2014)
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