| [article] 
					| Titre : | Task dependent prefrontal dysfunction in persons with Asperger's disorder investigated with multi-channel near-infrared spectroscopy |  
					| Type de document : | texte imprimé |  
					| Auteurs : | Akira IWANAMI, Auteur ; Yuka OKAJIMA, Auteur ; Haruhisa OTA, Auteur ; Masayuki TANI, Auteur ; Takashi YAMADA, Auteur ; Ryuichiro HASHIMORO, Auteur ; Chieko KANAI, Auteur ; Hiromi WATANABE, Auteur ; Hidenori YAMASUE, Auteur ; Yuki KAWAKUBO, Auteur ; Nobumasa KATO, Auteur |  
					| Année de publication : | 2011 |  
					| Article en page(s) : | p.1187-1193 |  
					| Langues : | Anglais (eng) |  
					| Mots-clés : | Asperger's disorder  PDD  NIRS  Prefrontal dysfunction  Verbal fluency task |  
					| Index. décimale : | PER Périodiques |  
					| Résumé : | Dysfunction of the prefrontal cortex has been previously reported in individuals with Asperger's disorder. In the present study, we used multi-channel near-infrared spectroscopy (NIRS) to detect changes in the oxygenated hemoglobin concentration ([oxy-Hb]) during two verbal fluency tasks. The subjects were 20 individuals with Asperger's disorder and 18 age- and IQ-matched healthy controls. The relative [oxy-Hb] in the prefrontal cortex was measured during the category and letter fluency tasks. The mean total [oxy-Hb] during the category fluency task did not differ significantly between the groups; however, during the letter fluency task, the mean [oxy-Hb] in persons with Asperger's disorder was significantly lower than that in controls. These results suggested task-relevant or task-specific prefrontal dysfunction in persons with Asperger's disorder. |  
					| En ligne : | http://dx.doi.org/10.1016/j.rasd.2011.01.005 |  
					| Permalink : | https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119 |  in Research in Autism Spectrum Disorders > 5-3  (July-September 2011) . - p.1187-1193
 [article] Task dependent prefrontal dysfunction in persons with Asperger's disorder investigated with multi-channel near-infrared spectroscopy [texte imprimé] / Akira IWANAMI , Auteur ; Yuka OKAJIMA , Auteur ; Haruhisa OTA , Auteur ; Masayuki TANI , Auteur ; Takashi YAMADA , Auteur ; Ryuichiro HASHIMORO , Auteur ; Chieko KANAI , Auteur ; Hiromi WATANABE , Auteur ; Hidenori YAMASUE , Auteur ; Yuki KAWAKUBO , Auteur ; Nobumasa KATO , Auteur . - 2011 . - p.1187-1193.Langues  : Anglais (eng )in Research in Autism Spectrum Disorders  > 5-3  (July-September 2011)  . - p.1187-1193 
					| Mots-clés : | Asperger's disorder  PDD  NIRS  Prefrontal dysfunction  Verbal fluency task |  
					| Index. décimale : | PER Périodiques |  
					| Résumé : | Dysfunction of the prefrontal cortex has been previously reported in individuals with Asperger's disorder. In the present study, we used multi-channel near-infrared spectroscopy (NIRS) to detect changes in the oxygenated hemoglobin concentration ([oxy-Hb]) during two verbal fluency tasks. The subjects were 20 individuals with Asperger's disorder and 18 age- and IQ-matched healthy controls. The relative [oxy-Hb] in the prefrontal cortex was measured during the category and letter fluency tasks. The mean total [oxy-Hb] during the category fluency task did not differ significantly between the groups; however, during the letter fluency task, the mean [oxy-Hb] in persons with Asperger's disorder was significantly lower than that in controls. These results suggested task-relevant or task-specific prefrontal dysfunction in persons with Asperger's disorder. |  
					| En ligne : | http://dx.doi.org/10.1016/j.rasd.2011.01.005 |  
					| Permalink : | https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119 | 
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