[article] 
inResearch in Autism Spectrum Disorders > 5-3 (July-September 2011) . - p.1187-1193

Titre :	Task dependent prefrontal dysfunction in persons with Asperger's disorder investigated with multi-channel near-infrared spectroscopy
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Akira IWANAMI, Auteur ; Yuka OKAJIMA, Auteur ; Haruhisa OTA, Auteur ; Masayuki TANI, Auteur ; Takashi YAMADA, Auteur ; Ryuichiro HASHIMORO, Auteur ; Chieko KANAI, Auteur ; Hiromi WATANABE, Auteur ; Hidenori YAMASUE, Auteur ; Yuki KAWAKUBO, Auteur ; Nobumasa KATO, Auteur
Année de publication :	2011
Article en page(s) :	p.1187-1193
Langues :	Anglais (eng)
Mots-clés :	Asperger's disorder  PDD  NIRS  Prefrontal dysfunction  Verbal fluency task
Index. décimale :	PER Périodiques
Résumé :	Dysfunction of the prefrontal cortex has been previously reported in individuals with Asperger's disorder. In the present study, we used multi-channel near-infrared spectroscopy (NIRS) to detect changes in the oxygenated hemoglobin concentration ([oxy-Hb]) during two verbal fluency tasks. The subjects were 20 individuals with Asperger's disorder and 18 age- and IQ-matched healthy controls. The relative [oxy-Hb] in the prefrontal cortex was measured during the category and letter fluency tasks. The mean total [oxy-Hb] during the category fluency task did not differ significantly between the groups; however, during the letter fluency task, the mean [oxy-Hb] in persons with Asperger's disorder was significantly lower than that in controls. These results suggested task-relevant or task-specific prefrontal dysfunction in persons with Asperger's disorder.
En ligne :	http://dx.doi.org/10.1016/j.rasd.2011.01.005
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119

[article] Task dependent prefrontal dysfunction in persons with Asperger's disorder investigated with multi-channel near-infrared spectroscopy [Texte imprimé et/ou numérique] / Akira IWANAMI, Auteur ; Yuka OKAJIMA, Auteur ; Haruhisa OTA, Auteur ; Masayuki TANI, Auteur ; Takashi YAMADA, Auteur ; Ryuichiro HASHIMORO, Auteur ; Chieko KANAI, Auteur ; Hiromi WATANABE, Auteur ; Hidenori YAMASUE, Auteur ; Yuki KAWAKUBO, Auteur ; Nobumasa KATO, Auteur . - 2011 . - p.1187-1193.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 5-3 (July-September 2011) . - p.1187-1193

Mots-clés :	Asperger's disorder  PDD  NIRS  Prefrontal dysfunction  Verbal fluency task
Index. décimale :	PER Périodiques
Résumé :	Dysfunction of the prefrontal cortex has been previously reported in individuals with Asperger's disorder. In the present study, we used multi-channel near-infrared spectroscopy (NIRS) to detect changes in the oxygenated hemoglobin concentration ([oxy-Hb]) during two verbal fluency tasks. The subjects were 20 individuals with Asperger's disorder and 18 age- and IQ-matched healthy controls. The relative [oxy-Hb] in the prefrontal cortex was measured during the category and letter fluency tasks. The mean total [oxy-Hb] during the category fluency task did not differ significantly between the groups; however, during the letter fluency task, the mean [oxy-Hb] in persons with Asperger's disorder was significantly lower than that in controls. These results suggested task-relevant or task-specific prefrontal dysfunction in persons with Asperger's disorder.
En ligne :	http://dx.doi.org/10.1016/j.rasd.2011.01.005
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=119