[article] 
inJournal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.545-554

Titre :	A Pilot Randomized Controlled Trial of Omega-3 Fatty Acids for Autism Spectrum Disorder
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Stephen BENT, Auteur ; Kiah BERTOGLIO, Auteur ; Paul ASHWOOD, Auteur ; Alan BOSTROM, Auteur ; Robert L. HENDREN, Auteur
Année de publication :	2011
Article en page(s) :	p.545-554
Langues :	Anglais (eng)
Mots-clés :	Autism  Omega-3 fatty acids  Complementary and alternative medicine  Clinical trial
Index. décimale :	PER Périodiques
Résumé :	We conducted a pilot randomized controlled trial to determine the feasibility and initial safety and efficacy of omega-3 fatty acids (1.3 g/day) for the treatment of hyperactivity in 27 children ages 3–8 with autism spectrum disorder (ASD). After 12 weeks, hyperactivity, as measured by the Aberrant Behavior Checklist, improved 2.7 (±4.8) points in the omega-3 group compared to 0.3 (±7.2) points in the placebo group (p = 0.40; effect size = 0.38). Correlations were found between decreases in five fatty acid levels and decreases in hyperactivity, and the treatment was well tolerated. Although this pilot study did not find a statistically significant benefit from omega-3 fatty acids, the small sample size does not rule out small to moderate beneficial effects.
En ligne :	http://dx.doi.org/10.1007/s10803-010-1078-8
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121

[article] A Pilot Randomized Controlled Trial of Omega-3 Fatty Acids for Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Stephen BENT, Auteur ; Kiah BERTOGLIO, Auteur ; Paul ASHWOOD, Auteur ; Alan BOSTROM, Auteur ; Robert L. HENDREN, Auteur . - 2011 . - p.545-554.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-5 (May 2011) . - p.545-554

Mots-clés :	Autism  Omega-3 fatty acids  Complementary and alternative medicine  Clinical trial
Index. décimale :	PER Périodiques
Résumé :	We conducted a pilot randomized controlled trial to determine the feasibility and initial safety and efficacy of omega-3 fatty acids (1.3 g/day) for the treatment of hyperactivity in 27 children ages 3–8 with autism spectrum disorder (ASD). After 12 weeks, hyperactivity, as measured by the Aberrant Behavior Checklist, improved 2.7 (±4.8) points in the omega-3 group compared to 0.3 (±7.2) points in the placebo group (p = 0.40; effect size = 0.38). Correlations were found between decreases in five fatty acid levels and decreases in hyperactivity, and the treatment was well tolerated. Although this pilot study did not find a statistically significant benefit from omega-3 fatty acids, the small sample size does not rule out small to moderate beneficial effects.
En ligne :	http://dx.doi.org/10.1007/s10803-010-1078-8
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=121