Evaluation of Appetite-Regulating Hormones ?n Young Children with Autism Spectrum Disorder / Ça?la ÇELIKKOL SADIÇ in Journal of Autism and Developmental Disorders, 51-2 (February 2021)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 51-2 (February 2021) . - p.632-643 Titre : Evaluation of Appetite-Regulating Hormones ?n Young Children with Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Ça?la ÇELIKKOL SADIÇ, Auteur ; Ayhan BILGIC, Auteur ; ?brahim KILINÇ, Auteur ; Mehmet Burhan OFLAZ, Auteur ; Tamer BAYSAL, Auteur Article en page(s) : p.632-643 Langues : Anglais (eng) Mots-clés : Autism  Early childhood  Ghrelin  Leptin  Nesfatin-1  Neuropeptide Y Index. décimale : PER Périodiques Résumé : This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04579-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440 [article] Evaluation of Appetite-Regulating Hormones ?n Young Children with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Ça?la ÇELIKKOL SADIÇ, Auteur ; Ayhan BILGIC, Auteur ; ?brahim KILINÇ, Auteur ; Mehmet Burhan OFLAZ, Auteur ; Tamer BAYSAL, Auteur . - p.632-643. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 51-2 (February 2021) . - p.632-643 Mots-clés : Autism  Early childhood  Ghrelin  Leptin  Nesfatin-1  Neuropeptide Y Index. décimale : PER Périodiques Résumé : This study aimed to investigate the role of leptin, ghrelin, neuropeptide Y, and nesfatin-1 in young children with autism spectrum disorder (ASD). A total of 44 children with ASD and 44 healthy controls aged 18-60 months were included. Plasma levels of hormones were measured using commercial enzyme-linked immunosorbent assay kits. Plasma leptin and ghrelin levels were significantly higher in the ASD group than in the control group. However, no significant difference for plasma neuropeptide Y and nesfatin-1 levels was detected between the groups. No relation was found between the severity of ASD symptoms, severity of eating problems, and plasma levels of hormones. Leptin and ghrelin may play a potential role in the pathogenesis of ASD. En ligne : http://dx.doi.org/10.1007/s10803-020-04579-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=440

Iron deficiency in preschool children with autistic spectrum disorders / Ayhan BILGIC in Research in Autism Spectrum Disorders, 4-4 (October-December 2010)  

Public ISBD [article]  inResearch in Autism Spectrum Disorders > 4-4 (October-December 2010) . - p.639-644 Titre : Iron deficiency in preschool children with autistic spectrum disorders Type de document : Texte imprimé et/ou numérique Auteurs : Ayhan BILGIC, Auteur ; Kagan GURKAN, Auteur ; Serhat TURKOGLU, Auteur ; Ömer Faruk AKCA, Auteur ; Birim Günay KILIC, Auteur ; Runa USLU, Auteur Année de publication : 2010 Article en page(s) : p.639-644 Langues : Anglais (eng) Mots-clés : Iron-deficiency Ferritin Autistic-spectrum-disorders Preschool-children Behavioral-problems Index. décimale : PER Périodiques Résumé : Iron deficiency (ID) cause negative outcomes on psychomotor and behavioral development of infants and young children. Children with autistic spectrum disorders (ASD) are under risk for ID and this condition may increase the severity of psychomotor and behavioral problems, some of which already inherently exist in these children. In the present study, the frequency of ID and the association between ID and autistic symptoms, developmental level, and behavioral problems in preschool children attending a clinic for ASD (N = 31) were evaluated. No association was observed between ID and the severity of autistic symptoms, developmental level and behavioral problems. ID was detected in 32.3% (N = 10) of the children based on serum ferritin level. In this study, the negative impact of low serum ferritin in ASD has not been confirmed. On the other hand, the rate of ID was considerably high in this sample of children with ASD compared to normative data of preschool children. Further studies with larger samples are needed to clarify the relationship between ID and clinical variables associated with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.12.008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102 [article] Iron deficiency in preschool children with autistic spectrum disorders [Texte imprimé et/ou numérique] / Ayhan BILGIC, Auteur ; Kagan GURKAN, Auteur ; Serhat TURKOGLU, Auteur ; Ömer Faruk AKCA, Auteur ; Birim Günay KILIC, Auteur ; Runa USLU, Auteur . - 2010 . - p.639-644. Langues : Anglais (eng) in Research in Autism Spectrum Disorders > 4-4 (October-December 2010) . - p.639-644 Mots-clés : Iron-deficiency Ferritin Autistic-spectrum-disorders Preschool-children Behavioral-problems Index. décimale : PER Périodiques Résumé : Iron deficiency (ID) cause negative outcomes on psychomotor and behavioral development of infants and young children. Children with autistic spectrum disorders (ASD) are under risk for ID and this condition may increase the severity of psychomotor and behavioral problems, some of which already inherently exist in these children. In the present study, the frequency of ID and the association between ID and autistic symptoms, developmental level, and behavioral problems in preschool children attending a clinic for ASD (N = 31) were evaluated. No association was observed between ID and the severity of autistic symptoms, developmental level and behavioral problems. ID was detected in 32.3% (N = 10) of the children based on serum ferritin level. In this study, the negative impact of low serum ferritin in ASD has not been confirmed. On the other hand, the rate of ID was considerably high in this sample of children with ASD compared to normative data of preschool children. Further studies with larger samples are needed to clarify the relationship between ID and clinical variables associated with ASD. En ligne : http://dx.doi.org/10.1016/j.rasd.2009.12.008 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=102

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