Automatic Evaluations in Clinically Anxious and Nonanxious Children and Adolescents / Leentje VERVOORT in Journal of Clinical Child & Adolescent Psychology, 39-4 (July-August 2010)  

Public ISBD [article]  inJournal of Clinical Child & Adolescent Psychology > 39-4 (July-August 2010) . - p.481-491 Titre : Automatic Evaluations in Clinically Anxious and Nonanxious Children and Adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Leentje VERVOORT, Auteur ; Lidewij H. WOLTERS, Auteur ; Sanne M. HOGENDOORN, Auteur ; Pier J. M. PRINS, Auteur ; Else DE HAAN, Auteur ; Maaike H. NAUTA, Auteur ; Frits BOER, Auteur Année de publication : 2010 Article en page(s) : p.481-491 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Automatic evaluations of clinically anxious and nonanxious children (n = 40, aged 8-16, 18 girls) were compared using a pictorial performance-based measure of automatic affective associations. Results showed a threat-related evaluation bias in clinically anxious but not in nonanxious children. In anxious participants, automatic evaluations of anxiety-relevant stimuli were more negative than those of negative stimuli. In nonanxious participants, evaluations of negative and anxiety-relevant stimuli did not differ. Furthermore, anxious youth had stronger negative evaluations of anxiety-relevant stimuli than nonanxious children. Automatic evaluations of positive, neutral, and negative stimuli did not differ between groups. Threat-related evaluations were predictive of parent-reported, but not child-reported, anxiety. En ligne : http://dx.doi.org/10.1080/15374416.2010.486316 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108 [article] Automatic Evaluations in Clinically Anxious and Nonanxious Children and Adolescents [Texte imprimé et/ou numérique] / Leentje VERVOORT, Auteur ; Lidewij H. WOLTERS, Auteur ; Sanne M. HOGENDOORN, Auteur ; Pier J. M. PRINS, Auteur ; Else DE HAAN, Auteur ; Maaike H. NAUTA, Auteur ; Frits BOER, Auteur . - 2010 . - p.481-491. Langues : Anglais (eng) in Journal of Clinical Child & Adolescent Psychology > 39-4 (July-August 2010) . - p.481-491 Index. décimale : PER Périodiques Résumé : Automatic evaluations of clinically anxious and nonanxious children (n = 40, aged 8-16, 18 girls) were compared using a pictorial performance-based measure of automatic affective associations. Results showed a threat-related evaluation bias in clinically anxious but not in nonanxious children. In anxious participants, automatic evaluations of anxiety-relevant stimuli were more negative than those of negative stimuli. In nonanxious participants, evaluations of negative and anxiety-relevant stimuli did not differ. Furthermore, anxious youth had stronger negative evaluations of anxiety-relevant stimuli than nonanxious children. Automatic evaluations of positive, neutral, and negative stimuli did not differ between groups. Threat-related evaluations were predictive of parent-reported, but not child-reported, anxiety. En ligne : http://dx.doi.org/10.1080/15374416.2010.486316 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=108

Developmental aspects of error and high-conflict-related brain activity in pediatric obsessive–compulsive disorder: a fMRI study with a Flanker task before and after CBT / Chaim HUYSER in Journal of Child Psychology and Psychiatry, 52-12 (December 2011)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 52-12 (December 2011) . - p.1251-1260 Titre : Developmental aspects of error and high-conflict-related brain activity in pediatric obsessive–compulsive disorder: a fMRI study with a Flanker task before and after CBT Type de document : Texte imprimé et/ou numérique Auteurs : Chaim HUYSER, Auteur ; Dick J. VELTMAN, Auteur ; Lidewij H. WOLTERS, Auteur ; Else DE HAAN, Auteur ; Frits BOER, Auteur Année de publication : 2011 Article en page(s) : p.1251-1260 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Background:  Heightened error and conflict monitoring are considered central mechanisms in obsessive–compulsive disorder (OCD) and are associated with anterior cingulate cortex (ACC) function. Pediatric obsessive–compulsive patients provide an opportunity to investigate the development of this area and its associations with psychopathology. Methods:  Repeated measures were carried out using functional magnetic resonance imaging (fMRI) during the performance of an interference task, the arrow version of the Flanker paradigm, before and after cognitive-behavioral treatment of 25 medication-free pediatric obsessive–compulsive patients compared with age- and gender-matched healthy controls. Results:  During error trials compared to correct trials, pediatric OCD patients and controls showed an interaction effect of Group × Time × Age in the ACC and insula. This effect was mainly driven by an increased activation in older OCD subjects, which was also present after treatment. During high-conflict trials compared with low-conflict trials, a Group × Time × Age interaction effect was found in bilateral insula. This effect was driven by an increase of BOLD (blood oxygen level dependent) signal in older OCD patients before but not after treatment. In addition, a Group × Time interaction effect in dorsomedial prefrontal cortex, premotor region and ACC was found. This effect was driven by an increase of BOLD signal in OCD subjects relative to controls over time. Conclusions:  Compared to healthy controls, children and adolescents with OCD show increased activation of the ACC during error responses and in bilateral insular cortex during high-conflict tasks, which is age dependent and which is only partially affected by cognitive-behavioral therapy (CBT). Therefore, we suggest that ACC functioning is a vulnerability marker in pediatric OCD, whereas insular dysfunction may be state dependent. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02439.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146 [article] Developmental aspects of error and high-conflict-related brain activity in pediatric obsessive–compulsive disorder: a fMRI study with a Flanker task before and after CBT [Texte imprimé et/ou numérique] / Chaim HUYSER, Auteur ; Dick J. VELTMAN, Auteur ; Lidewij H. WOLTERS, Auteur ; Else DE HAAN, Auteur ; Frits BOER, Auteur . - 2011 . - p.1251-1260. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 52-12 (December 2011) . - p.1251-1260 Index. décimale : PER Périodiques Résumé : Background:  Heightened error and conflict monitoring are considered central mechanisms in obsessive–compulsive disorder (OCD) and are associated with anterior cingulate cortex (ACC) function. Pediatric obsessive–compulsive patients provide an opportunity to investigate the development of this area and its associations with psychopathology. Methods:  Repeated measures were carried out using functional magnetic resonance imaging (fMRI) during the performance of an interference task, the arrow version of the Flanker paradigm, before and after cognitive-behavioral treatment of 25 medication-free pediatric obsessive–compulsive patients compared with age- and gender-matched healthy controls. Results:  During error trials compared to correct trials, pediatric OCD patients and controls showed an interaction effect of Group × Time × Age in the ACC and insula. This effect was mainly driven by an increased activation in older OCD subjects, which was also present after treatment. During high-conflict trials compared with low-conflict trials, a Group × Time × Age interaction effect was found in bilateral insula. This effect was driven by an increase of BOLD (blood oxygen level dependent) signal in older OCD patients before but not after treatment. In addition, a Group × Time interaction effect in dorsomedial prefrontal cortex, premotor region and ACC was found. This effect was driven by an increase of BOLD signal in OCD subjects relative to controls over time. Conclusions:  Compared to healthy controls, children and adolescents with OCD show increased activation of the ACC during error responses and in bilateral insular cortex during high-conflict tasks, which is age dependent and which is only partially affected by cognitive-behavioral therapy (CBT). Therefore, we suggest that ACC functioning is a vulnerability marker in pediatric OCD, whereas insular dysfunction may be state dependent. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2011.02439.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=146

Temperament, Attentional Processes, and Anxiety: Diverging Links Between Adolescents With and Without Anxiety Disorders? / Leentje VERVOORT in Journal of Clinical Child & Adolescent Psychology, 40-1 (January-February 2011)  

Public ISBD [article]  inJournal of Clinical Child & Adolescent Psychology > 40-1 (January-February 2011) . - p.144-155 Titre : Temperament, Attentional Processes, and Anxiety: Diverging Links Between Adolescents With and Without Anxiety Disorders? Type de document : Texte imprimé et/ou numérique Auteurs : Leentje VERVOORT, Auteur ; Lidewij H. WOLTERS, Auteur ; Sanne M. HOGENDOORN, Auteur ; Pier J. M. PRINS, Auteur ; Else DE HAAN, Auteur ; Frits BOER, Auteur ; Catharina A. HARTMAN, Auteur Année de publication : 2011 Article en page(s) : p.144-155 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The present study first examined the links between reactive temperament (negative affectivity), regulative temperament (effortful control [EC]) and internalizing problems in adolescents (12-18 years) with anxiety disorders (ANX; N = 39) and without anxiety disorders (nANX; N = 35). Links differed between ANX and nANX participants. Negative affectivity predicted internalizing problems, with almost no role of EC in nANX, but a protective role of EC was found in ANX youth. Second, we investigated the role of attentional bias as a mediator between temperament and internalizing problems. Strategic threat-related bias was predicted by initial attention and EC, but these relations differed in both groups. In nANX participants, higher initial bias scores were predictive for lower strategic bias scores and higher levels of EC were associated with higher bias scores. In ANX participants, there was almost no effect of initial bias or EC on strategic attention. Internalizing problems were predicted by strategic attention, but again differently in ANX and nANX participants. High strategic bias scores were associated with an increase in anxiety in ANX and a decrease in anxiety in nANX participants. En ligne : http://dx.doi.org/10.1080/15374416.2011.533412 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=115 [article] Temperament, Attentional Processes, and Anxiety: Diverging Links Between Adolescents With and Without Anxiety Disorders? [Texte imprimé et/ou numérique] / Leentje VERVOORT, Auteur ; Lidewij H. WOLTERS, Auteur ; Sanne M. HOGENDOORN, Auteur ; Pier J. M. PRINS, Auteur ; Else DE HAAN, Auteur ; Frits BOER, Auteur ; Catharina A. HARTMAN, Auteur . - 2011 . - p.144-155. Langues : Anglais (eng) in Journal of Clinical Child & Adolescent Psychology > 40-1 (January-February 2011) . - p.144-155 Index. décimale : PER Périodiques Résumé : The present study first examined the links between reactive temperament (negative affectivity), regulative temperament (effortful control [EC]) and internalizing problems in adolescents (12-18 years) with anxiety disorders (ANX; N = 39) and without anxiety disorders (nANX; N = 35). Links differed between ANX and nANX participants. Negative affectivity predicted internalizing problems, with almost no role of EC in nANX, but a protective role of EC was found in ANX youth. Second, we investigated the role of attentional bias as a mediator between temperament and internalizing problems. Strategic threat-related bias was predicted by initial attention and EC, but these relations differed in both groups. In nANX participants, higher initial bias scores were predictive for lower strategic bias scores and higher levels of EC were associated with higher bias scores. In ANX participants, there was almost no effect of initial bias or EC on strategic attention. Internalizing problems were predicted by strategic attention, but again differently in ANX and nANX participants. High strategic bias scores were associated with an increase in anxiety in ANX and a decrease in anxiety in nANX participants. En ligne : http://dx.doi.org/10.1080/15374416.2011.533412 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=115

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