Dépouillements

Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits / Xin HE in Molecular Autism, (November 2015)  

Public ISBD [article]  inMolecular Autism > (November 2015) . - p.1-10 Titre : Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits Type de document : Texte imprimé et/ou numérique Auteurs : Xin HE, Auteur ; Stetson THACKER, Auteur ; Todd ROMIGH, Auteur ; Qi YU, Auteur ; Thomas W. FRAZIER, Auteur ; Charis ENG, Auteur Article en page(s) : p.1-10 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairment in social communication/interaction and inflexible/repetitive behavior. Several lines of evidence support genetic factors as a predominant cause of ASD. Among those autism susceptibility genes that have been identified, the PTEN tumor suppressor gene, initially identified as predisposing to Cowden heritable cancer syndrome, was found to be mutated in a subset of ASD patients with extreme macrocephaly. However, the ASD-relevant molecular mechanism mediating the effect of PTEN mutations remains elusive. En ligne : http://dx.doi.org/10.1186/s13229-015-0056-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] Cytoplasm-predominant Pten associates with increased region-specific brain tyrosine hydroxylase and dopamine D2 receptors in mouse model with autistic traits [Texte imprimé et/ou numérique] / Xin HE, Auteur ; Stetson THACKER, Auteur ; Todd ROMIGH, Auteur ; Qi YU, Auteur ; Thomas W. FRAZIER, Auteur ; Charis ENG, Auteur . - p.1-10. Langues : Anglais (eng) in Molecular Autism > (November 2015) . - p.1-10 Index. décimale : PER Périodiques Résumé : Autism spectrum disorder (ASD) is a group of neurodevelopmental disorders characterized by impairment in social communication/interaction and inflexible/repetitive behavior. Several lines of evidence support genetic factors as a predominant cause of ASD. Among those autism susceptibility genes that have been identified, the PTEN tumor suppressor gene, initially identified as predisposing to Cowden heritable cancer syndrome, was found to be mutated in a subset of ASD patients with extreme macrocephaly. However, the ASD-relevant molecular mechanism mediating the effect of PTEN mutations remains elusive. En ligne : http://dx.doi.org/10.1186/s13229-015-0056-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

A neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in mice / Emma L. BURROWS in Molecular Autism, (November 2015)  

Public ISBD [article]  inMolecular Autism > (November 2015) . - p.1-11 Titre : A neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in mice Type de document : Texte imprimé et/ou numérique Auteurs : Emma L. BURROWS, Auteur ; Liliana LASKARIS, Auteur ; Lynn KOYAMA, Auteur ; Leonid CHURILOV, Auteur ; Joel C. BORNSTEIN, Auteur ; Elisa L. HILL-YARDIN, Auteur ; Anthony J. HANNAN, Auteur Article en page(s) : p.1-11 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Aggression is common in patients with autism spectrum disorders (ASD) along with the core symptoms of impairments in social communication and repetitive behavior. Risperidone, an atypical antipsychotic, is widely used to treat aggression in ASD. In order to understand the neurobiological underpinnings of these challenging behaviors, a thorough characterisation of behavioral endophenotypes in animal models is required. En ligne : http://dx.doi.org/10.1186/s13229-015-0055-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] A neuroligin-3 mutation implicated in autism causes abnormal aggression and increases repetitive behavior in mice [Texte imprimé et/ou numérique] / Emma L. BURROWS, Auteur ; Liliana LASKARIS, Auteur ; Lynn KOYAMA, Auteur ; Leonid CHURILOV, Auteur ; Joel C. BORNSTEIN, Auteur ; Elisa L. HILL-YARDIN, Auteur ; Anthony J. HANNAN, Auteur . - p.1-11. Langues : Anglais (eng) in Molecular Autism > (November 2015) . - p.1-11 Index. décimale : PER Périodiques Résumé : Aggression is common in patients with autism spectrum disorders (ASD) along with the core symptoms of impairments in social communication and repetitive behavior. Risperidone, an atypical antipsychotic, is widely used to treat aggression in ASD. In order to understand the neurobiological underpinnings of these challenging behaviors, a thorough characterisation of behavioral endophenotypes in animal models is required. En ligne : http://dx.doi.org/10.1186/s13229-015-0055-7 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277

The autism inpatient collection: methods and preliminary sample description / Matthew SIEGEL in Molecular Autism, (November 2015)  

Public ISBD [article]  inMolecular Autism > (November 2015) . - p.1-10 Titre : The autism inpatient collection: methods and preliminary sample description Type de document : Texte imprimé et/ou numérique Auteurs : Matthew SIEGEL, Auteur ; Kahsi A. SMITH, Auteur ; Carla MAZEFSKY, Auteur ; Robin L. GABRIELS, Auteur ; Craig ERICKSON, Auteur ; Desmond KAPLAN, Auteur ; Eric M. MORROW, Auteur ; Logan WINK, Auteur ; Susan L. SANTANGELO, Auteur Article en page(s) : p.1-10 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Individuals severely affected by autism spectrum disorder (ASD), including those with intellectual disability, expressive language impairment, and/or self-injurious behavior (SIB), are underrepresented in the ASD literature and extant collections of phenotypic and biological data. An understanding of ASD’s etiology and subtypes can only be as complete as the studied samples are representative. En ligne : http://dx.doi.org/10.1186/s13229-015-0054-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277 [article] The autism inpatient collection: methods and preliminary sample description [Texte imprimé et/ou numérique] / Matthew SIEGEL, Auteur ; Kahsi A. SMITH, Auteur ; Carla MAZEFSKY, Auteur ; Robin L. GABRIELS, Auteur ; Craig ERICKSON, Auteur ; Desmond KAPLAN, Auteur ; Eric M. MORROW, Auteur ; Logan WINK, Auteur ; Susan L. SANTANGELO, Auteur . - p.1-10. Langues : Anglais (eng) in Molecular Autism > (November 2015) . - p.1-10 Index. décimale : PER Périodiques Résumé : Individuals severely affected by autism spectrum disorder (ASD), including those with intellectual disability, expressive language impairment, and/or self-injurious behavior (SIB), are underrepresented in the ASD literature and extant collections of phenotypic and biological data. An understanding of ASD’s etiology and subtypes can only be as complete as the studied samples are representative. En ligne : http://dx.doi.org/10.1186/s13229-015-0054-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=277