Interaction of 5-HTTLPR and Idiographic Stressors Predicts Prospective Depressive Symptoms Specifically Among Youth in a Multiwave Design / Benjamin L. HANKIN in Journal of Clinical Child & Adolescent Psychology, 40-4 (July-August 2011)  

Public ISBD [article]  inJournal of Clinical Child & Adolescent Psychology > 40-4 (July-August 2011) . - p.572-585 Titre : Interaction of 5-HTTLPR and Idiographic Stressors Predicts Prospective Depressive Symptoms Specifically Among Youth in a Multiwave Design Type de document : Texte imprimé et/ou numérique Auteurs : Benjamin L. HANKIN, Auteur ; Jessica L. JENNESS, Auteur ; John R. Z. ABELA, Auteur ; Andrew SMOLEN, Auteur Année de publication : 2011 Article en page(s) : p.572-585 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : 5-HTTLPR, episodic stressors, depressive and anxious symptoms were assessed prospectively (child and parent report) every 3 months over 1 year (5 waves of data) among community youth ages 9 to 15 (n = 220). Lagged hierarchical linear modeling analyses showed 5-HTTLPR interacted with idiographic stressors (increases relative to the child's own average level over time), but not nomothetic stressors (higher stress exposure relative to the sample), to predict prospective elevations in depressive, but not anxious, symptoms. Youth with copies of the S or LG alleles of 5-HTTLPR, who experienced more stressors relative to their typical level, exhibited prospective increases in depressive symptoms over time. These findings suggest that 5-HTTLPR confers susceptibility to depression via stress reactivity. En ligne : http://dx.doi.org/10.1080/15374416.2011.581613 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132 [article] Interaction of 5-HTTLPR and Idiographic Stressors Predicts Prospective Depressive Symptoms Specifically Among Youth in a Multiwave Design [Texte imprimé et/ou numérique] / Benjamin L. HANKIN, Auteur ; Jessica L. JENNESS, Auteur ; John R. Z. ABELA, Auteur ; Andrew SMOLEN, Auteur . - 2011 . - p.572-585. Langues : Anglais (eng) in Journal of Clinical Child & Adolescent Psychology > 40-4 (July-August 2011) . - p.572-585 Index. décimale : PER Périodiques Résumé : 5-HTTLPR, episodic stressors, depressive and anxious symptoms were assessed prospectively (child and parent report) every 3 months over 1 year (5 waves of data) among community youth ages 9 to 15 (n = 220). Lagged hierarchical linear modeling analyses showed 5-HTTLPR interacted with idiographic stressors (increases relative to the child's own average level over time), but not nomothetic stressors (higher stress exposure relative to the sample), to predict prospective elevations in depressive, but not anxious, symptoms. Youth with copies of the S or LG alleles of 5-HTTLPR, who experienced more stressors relative to their typical level, exhibited prospective increases in depressive symptoms over time. These findings suggest that 5-HTTLPR confers susceptibility to depression via stress reactivity. En ligne : http://dx.doi.org/10.1080/15374416.2011.581613 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=132

Observed positive parenting behaviors and youth genotype: Evidence for gene–environment correlations and moderation by parent personality traits / Caroline W. OPPENHEIMER in Development and Psychopathology, 25-1 (February 2013)  

Public ISBD [article]  inDevelopment and Psychopathology > 25-1 (February 2013) . - p.175-191 Titre : Observed positive parenting behaviors and youth genotype: Evidence for gene–environment correlations and moderation by parent personality traits Type de document : Texte imprimé et/ou numérique Auteurs : Caroline W. OPPENHEIMER, Auteur ; Benjamin L. HANKIN, Auteur ; Jessica L. JENNESS, Auteur ; Jami F. YOUNG, Auteur ; Andrew SMOLEN, Auteur Article en page(s) : p.175-191 Index. décimale : PER Périodiques Résumé : Gene–environment correlations (rGE) have been demonstrated in behavioral genetic studies, but rGE have proven elusive in molecular genetic research. Significant gene–environment correlations may be difficult to detect because potential moderators could reduce correlations between measured genetic variants and the environment. Molecular genetic studies investigating moderated rGE are lacking. This study examined associations between child catechol-O-methyltransferase genotype and aspects of positive parenting (responsiveness and warmth), and whether these associations were moderated by parental personality traits (neuroticism and extraversion) among a general community sample of third, sixth, and ninth graders (N = 263) and their parents. Results showed that parent personality traits moderated the rGE association between youths' genotype and coded observations of positive parenting. Parents with low levels of neuroticism and high levels of extraversion exhibited greater sensitive responsiveness and warmth, respectively, to youth with the valine/valine genotype. Moreover, youth with this genotype exhibited lower levels of observed anger. There was no association between the catechol-O-methyltransferase genotype and parenting behaviors for parents high on neuroticism and low on extraversion. Findings highlight the importance of considering moderating variables that may influence child genetic effects on the rearing environment. Implications for developmental models of maladaptive and adaptive child outcomes, and interventions for psychopathology, are discussed within a developmental psychopathology framework. En ligne : http://dx.doi.org/10.1017/S0954579412000983 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=190 [article] Observed positive parenting behaviors and youth genotype: Evidence for gene–environment correlations and moderation by parent personality traits [Texte imprimé et/ou numérique] / Caroline W. OPPENHEIMER, Auteur ; Benjamin L. HANKIN, Auteur ; Jessica L. JENNESS, Auteur ; Jami F. YOUNG, Auteur ; Andrew SMOLEN, Auteur . - p.175-191. in Development and Psychopathology > 25-1 (February 2013) . - p.175-191 Index. décimale : PER Périodiques Résumé : Gene–environment correlations (rGE) have been demonstrated in behavioral genetic studies, but rGE have proven elusive in molecular genetic research. Significant gene–environment correlations may be difficult to detect because potential moderators could reduce correlations between measured genetic variants and the environment. Molecular genetic studies investigating moderated rGE are lacking. This study examined associations between child catechol-O-methyltransferase genotype and aspects of positive parenting (responsiveness and warmth), and whether these associations were moderated by parental personality traits (neuroticism and extraversion) among a general community sample of third, sixth, and ninth graders (N = 263) and their parents. Results showed that parent personality traits moderated the rGE association between youths' genotype and coded observations of positive parenting. Parents with low levels of neuroticism and high levels of extraversion exhibited greater sensitive responsiveness and warmth, respectively, to youth with the valine/valine genotype. Moreover, youth with this genotype exhibited lower levels of observed anger. There was no association between the catechol-O-methyltransferase genotype and parenting behaviors for parents high on neuroticism and low on extraversion. Findings highlight the importance of considering moderating variables that may influence child genetic effects on the rearing environment. Implications for developmental models of maladaptive and adaptive child outcomes, and interventions for psychopathology, are discussed within a developmental psychopathology framework. En ligne : http://dx.doi.org/10.1017/S0954579412000983 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=190

Parenting and adolescents’ psychological adjustment: Longitudinal moderation by adolescents’ genetic sensitivity / Clare M. STOCKER in Development and Psychopathology, 29-4 (October 2017)  

Public ISBD [article]  inDevelopment and Psychopathology > 29-4 (October 2017) . - p.1289-1304 Titre : Parenting and adolescents’ psychological adjustment: Longitudinal moderation by adolescents’ genetic sensitivity Type de document : Texte imprimé et/ou numérique Auteurs : Clare M. STOCKER, Auteur ; April S. MASARIK, Auteur ; Keith F. WIDAMAN, Auteur ; Ben T. REEB, Auteur ; Jason D. BOARDMAN, Auteur ; Andrew SMOLEN, Auteur ; Tricia K. NEPPL, Auteur ; Katherine J. CONGER, Auteur Article en page(s) : p.1289-1304 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract We examined whether adolescents’ genetic sensitivity, measured by a polygenic index score, moderated the longitudinal associations between parenting and adolescents’ psychological adjustment. The sample included 323 mothers, fathers, and adolescents (177 female, 146 male; Time 1 [T1] average age = 12.61 years, SD = 0.54 years; Time 2 [T2] average age = 13.59 years, SD = 0.59 years). Parents’ warmth and hostility were rated by trained, independent observers using videotapes of family discussions. Adolescents reported their symptoms of anxiety, depressed mood, and hostility at T1 and T2. The results from autoregressive linear regression models showed that adolescents’ genetic sensitivity moderated associations between observations of both mothers’ and fathers’ T1 parenting and adolescents’ T2 composite maladjustment, depression, anxiety, and hostility. Compared to adolescents with low genetic sensitivity, adolescents with high genetic sensitivity had worse adjustment outcomes when parenting was low on warmth and high on hostility. When parenting was characterized by high warmth and low hostility, adolescents with high genetic sensitivity had better adjustment outcomes than their counterparts with low genetic sensitivity. The results support the differential susceptibility model and highlight the complex ways that genes and environment interact to influence development. En ligne : http://dx.doi.org/10.1017/s0954579416001310 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312 [article] Parenting and adolescents’ psychological adjustment: Longitudinal moderation by adolescents’ genetic sensitivity [Texte imprimé et/ou numérique] / Clare M. STOCKER, Auteur ; April S. MASARIK, Auteur ; Keith F. WIDAMAN, Auteur ; Ben T. REEB, Auteur ; Jason D. BOARDMAN, Auteur ; Andrew SMOLEN, Auteur ; Tricia K. NEPPL, Auteur ; Katherine J. CONGER, Auteur . - p.1289-1304. Langues : Anglais (eng) in Development and Psychopathology > 29-4 (October 2017) . - p.1289-1304 Index. décimale : PER Périodiques Résumé : Abstract We examined whether adolescents’ genetic sensitivity, measured by a polygenic index score, moderated the longitudinal associations between parenting and adolescents’ psychological adjustment. The sample included 323 mothers, fathers, and adolescents (177 female, 146 male; Time 1 [T1] average age = 12.61 years, SD = 0.54 years; Time 2 [T2] average age = 13.59 years, SD = 0.59 years). Parents’ warmth and hostility were rated by trained, independent observers using videotapes of family discussions. Adolescents reported their symptoms of anxiety, depressed mood, and hostility at T1 and T2. The results from autoregressive linear regression models showed that adolescents’ genetic sensitivity moderated associations between observations of both mothers’ and fathers’ T1 parenting and adolescents’ T2 composite maladjustment, depression, anxiety, and hostility. Compared to adolescents with low genetic sensitivity, adolescents with high genetic sensitivity had worse adjustment outcomes when parenting was low on warmth and high on hostility. When parenting was characterized by high warmth and low hostility, adolescents with high genetic sensitivity had better adjustment outcomes than their counterparts with low genetic sensitivity. The results support the differential susceptibility model and highlight the complex ways that genes and environment interact to influence development. En ligne : http://dx.doi.org/10.1017/s0954579416001310 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312

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