[article]
| Titre : |
Digit Ratio 2D:4D in Relation to Autism Spectrum Disorders, Empathizing, and Systemizing: A Quantitative Review |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Johannes HONEKOPP, Auteur |
| Année de publication : |
2012 |
| Article en page(s) : |
p.221-30 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
autism digit ratio prenatal testosterone empathizing systemizing sex differences |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Prenatal testosterone (PT) effects have been proposed to increase systemizing (the drive to understand lawful input–output relationships), to decrease empathizing (the drive to understand others), and to cause autism via hypermasculinization of the brain. Digit ratio 2D:4D is a putative marker of PT effects in humans. An online study (n = 1896) into the relationship between the Reading the Mind in the Eyes Test (a widely used measure of empathizing) and self-measured 2D:4D in a nonclinical sample is reported. No evidence for a link between empathizing and 2D:4D in either females or males emerged. Further, three meta-analyses are presented that look into the relationships of 2D:4D with autism spectrum disorder (ASD), systemizing, and empathizing. 2D:4D was substantially lower (more masculine) in ASD-affected individuals than in normal controls (d = −0.58, P < 0.001). However, 2D:4D was found to be virtually unrelated to systemizing and empathizing in normal adults. The results support the idea that high PT is a risk factor for autism, but they challenge the view that PT substantially contributes to sex differences in systemizing and empathizing. Possibly, this pattern reflects an interaction effect, whereby PT drives ASD characteristic changes only in brains with a specific damage. |
| En ligne : |
http://dx.doi.org/10.1002/aur.1230 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=179 |
in Autism Research > 5-4 (August 2012) . - p.221-30
[article] Digit Ratio 2D:4D in Relation to Autism Spectrum Disorders, Empathizing, and Systemizing: A Quantitative Review [Texte imprimé et/ou numérique] / Johannes HONEKOPP, Auteur . - 2012 . - p.221-30. Langues : Anglais ( eng) in Autism Research > 5-4 (August 2012) . - p.221-30
| Mots-clés : |
autism digit ratio prenatal testosterone empathizing systemizing sex differences |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Prenatal testosterone (PT) effects have been proposed to increase systemizing (the drive to understand lawful input–output relationships), to decrease empathizing (the drive to understand others), and to cause autism via hypermasculinization of the brain. Digit ratio 2D:4D is a putative marker of PT effects in humans. An online study (n = 1896) into the relationship between the Reading the Mind in the Eyes Test (a widely used measure of empathizing) and self-measured 2D:4D in a nonclinical sample is reported. No evidence for a link between empathizing and 2D:4D in either females or males emerged. Further, three meta-analyses are presented that look into the relationships of 2D:4D with autism spectrum disorder (ASD), systemizing, and empathizing. 2D:4D was substantially lower (more masculine) in ASD-affected individuals than in normal controls (d = −0.58, P < 0.001). However, 2D:4D was found to be virtually unrelated to systemizing and empathizing in normal adults. The results support the idea that high PT is a risk factor for autism, but they challenge the view that PT substantially contributes to sex differences in systemizing and empathizing. Possibly, this pattern reflects an interaction effect, whereby PT drives ASD characteristic changes only in brains with a specific damage. |
| En ligne : |
http://dx.doi.org/10.1002/aur.1230 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=179 |
|  |
Digit Ratio 2D:4D in Relation to Autism Spectrum Disorders, Empathizing, and Systemizing: A Quantitative Review in Autism Research, 5-4 (August 2012)
