Commentary: The challenges and promises of competitively employing autistic adults in the United States / Jo A. YON-HERNÁNDEZ ; Steve RUDER ; Surina BOTHRA ; Catherine GONZALES ; Kali KECSKEMETI ; Yukari TAKARAE in Autism Research, 16-11 (November 2023)  

Public ISBD [article]  inAutism Research > 16-11 (November 2023) . - p.2054-2060 Titre : Commentary: The challenges and promises of competitively employing autistic adults in the United States Type de document : texte imprimé Auteurs : Jo A. YON-HERNÁNDEZ, Auteur ; Steve RUDER, Auteur ; Surina BOTHRA, Auteur ; Catherine GONZALES, Auteur ; Kali KECSKEMETI, Auteur ; Yukari TAKARAE, Auteur Article en page(s) : p.2054-2060 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Current United States statistics suggest that autistic individuals will experience high unemployment and underemployment rates throughout their lives. Furthermore, despite the passage of federal legislation to employ young autistic adults in competitive integrated settings, where they work alongside non-disabled workers and earn at least minimum wage, most individuals receiving state services still are placed in day programs or sheltered workshops. Since meaningful employment is the most important determinant of life satisfaction, this failure is a critical societal problem, exerting increasing pressure for systems change. But the news is not all bad. Private sector companies have increased their hiring of disabled workers, producing a growing base of expertise in the recruitment, on-boarding, training, and management of autistic employees. This has led to a growing recognition that autistic individuals can be ideal workers. Autism researchers have advanced the field by investigating these private industry programs as well as conducting efficacy trials of interventions and services that help autistic individuals in the workplace. However, gaps in knowledge persist stemming from the heterogeneity of autistic workers, limited knowledge about those not receiving state services, and a system of federal services that is fragmented, poorly coordinated, difficult to navigate, and over-taxed. Autism researchers can continue to improve outcomes of autistic workers through investigations of the fit between autistic workers, their preferences, and the characteristics of available jobs, and through effectiveness trails of promising employment interventions and services that promote systems change that help break down the barriers to better integration of existing state services and resources in the United States. En ligne : https://doi.org/10.1002/aur.3009 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517 [article] Commentary: The challenges and promises of competitively employing autistic adults in the United States [texte imprimé] / Jo A. YON-HERNÁNDEZ, Auteur ; Steve RUDER, Auteur ; Surina BOTHRA, Auteur ; Catherine GONZALES, Auteur ; Kali KECSKEMETI, Auteur ; Yukari TAKARAE, Auteur . - p.2054-2060. Langues : Anglais (eng) in Autism Research > 16-11 (November 2023) . - p.2054-2060 Index. décimale : PER Périodiques Résumé : Abstract Current United States statistics suggest that autistic individuals will experience high unemployment and underemployment rates throughout their lives. Furthermore, despite the passage of federal legislation to employ young autistic adults in competitive integrated settings, where they work alongside non-disabled workers and earn at least minimum wage, most individuals receiving state services still are placed in day programs or sheltered workshops. Since meaningful employment is the most important determinant of life satisfaction, this failure is a critical societal problem, exerting increasing pressure for systems change. But the news is not all bad. Private sector companies have increased their hiring of disabled workers, producing a growing base of expertise in the recruitment, on-boarding, training, and management of autistic employees. This has led to a growing recognition that autistic individuals can be ideal workers. Autism researchers have advanced the field by investigating these private industry programs as well as conducting efficacy trials of interventions and services that help autistic individuals in the workplace. However, gaps in knowledge persist stemming from the heterogeneity of autistic workers, limited knowledge about those not receiving state services, and a system of federal services that is fragmented, poorly coordinated, difficult to navigate, and over-taxed. Autism researchers can continue to improve outcomes of autistic workers through investigations of the fit between autistic workers, their preferences, and the characteristics of available jobs, and through effectiveness trails of promising employment interventions and services that promote systems change that help break down the barriers to better integration of existing state services and resources in the United States. En ligne : https://doi.org/10.1002/aur.3009 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=517

A cross-sectional study of the development of volitional control of spatial attention in children with chromosome 22q11.2 deletion syndrome / Heather M. SHAPIRO in Journal of Neurodevelopmental Disorders, 4-1 (December 2012)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 4-1 (December 2012) . - p.5 Titre : A cross-sectional study of the development of volitional control of spatial attention in children with chromosome 22q11.2 deletion syndrome Type de document : texte imprimé Auteurs : Heather M. SHAPIRO, Auteur ; Yukari TAKARAE, Auteur ; Danielle J. HARVEY, Auteur ; Margarita H. CABARAL, Auteur ; Tony J. SIMON, Auteur Article en page(s) : p.5 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : BACKGROUND: Chromosome 22q11.2 deletion syndrome (22q11.2DS) results from a 1.5- to 3-megabase deletion on the long arm of chromosome 22 and occurs in approximately 1 in 4000 live births. Previous studies indicate that children with 22q11.2DS are impaired on tasks involving spatial attention. However, the degree to which these impairments are due to volitionally generated (endogenous) or reflexive (exogenous) orienting of attention is unclear. Additionally, the efficacy of these component attention processes throughout child development in 22q11.2DS has yet to be examined. METHODS: Here we compared the performance of a wide age range (7 to 14 years) of children with 22q11.2DS to typically developing (TD) children on a comprehensive visual cueing paradigm to dissociate the contributions of endogenous and exogenous attentional impairments. Paired and two-sample t-tests were used to compare outcome measures within a group or between groups. Additionally, repeated measures regression models were fit to the data in order to examine effects of age on performance. RESULTS: We found that children with 22q11.2DS were impaired on a cueing task with an endogenous cue, but not on the same task with an exogenous cue. Additionally, it was younger children exclusively who were impaired on endogenous cueing when compared to age-matched TD children. Older children with 22q11.2DS performed comparably to age-matched TD peers on the endogenous cueing task. CONCLUSIONS: These results suggest that endogenous but not exogenous orienting of attention is selectively impaired in children with 22q11.2DS. Additionally, the age effect on cueing in children with 22q11.2DS suggests a possible altered developmental trajectory of endogenous cueing. En ligne : http://dx.doi.org/10.1186/1866-1955-4-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=344 [article] A cross-sectional study of the development of volitional control of spatial attention in children with chromosome 22q11.2 deletion syndrome [texte imprimé] / Heather M. SHAPIRO, Auteur ; Yukari TAKARAE, Auteur ; Danielle J. HARVEY, Auteur ; Margarita H. CABARAL, Auteur ; Tony J. SIMON, Auteur . - p.5. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 4-1 (December 2012) . - p.5 Index. décimale : PER Périodiques Résumé : BACKGROUND: Chromosome 22q11.2 deletion syndrome (22q11.2DS) results from a 1.5- to 3-megabase deletion on the long arm of chromosome 22 and occurs in approximately 1 in 4000 live births. Previous studies indicate that children with 22q11.2DS are impaired on tasks involving spatial attention. However, the degree to which these impairments are due to volitionally generated (endogenous) or reflexive (exogenous) orienting of attention is unclear. Additionally, the efficacy of these component attention processes throughout child development in 22q11.2DS has yet to be examined. METHODS: Here we compared the performance of a wide age range (7 to 14 years) of children with 22q11.2DS to typically developing (TD) children on a comprehensive visual cueing paradigm to dissociate the contributions of endogenous and exogenous attentional impairments. Paired and two-sample t-tests were used to compare outcome measures within a group or between groups. Additionally, repeated measures regression models were fit to the data in order to examine effects of age on performance. RESULTS: We found that children with 22q11.2DS were impaired on a cueing task with an endogenous cue, but not on the same task with an exogenous cue. Additionally, it was younger children exclusively who were impaired on endogenous cueing when compared to age-matched TD children. Older children with 22q11.2DS performed comparably to age-matched TD peers on the endogenous cueing task. CONCLUSIONS: These results suggest that endogenous but not exogenous orienting of attention is selectively impaired in children with 22q11.2DS. Additionally, the age effect on cueing in children with 22q11.2DS suggests a possible altered developmental trajectory of endogenous cueing. En ligne : http://dx.doi.org/10.1186/1866-1955-4-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=344

Motor Functioning and Dyspraxia in Autism Spectrum Disorders / Matthew W. MOSCONI

Public ISBD in Autism Spectrum Disorders / David G. AMARAL Titre : Motor Functioning and Dyspraxia in Autism Spectrum Disorders Type de document : texte imprimé Auteurs : Matthew W. MOSCONI, Auteur ; Yukari TAKARAE, Auteur ; John A. SWEENEY, Auteur Année de publication : 2011 Importance : p.355-380 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139 in Autism Spectrum Disorders / David G. AMARAL Motor Functioning and Dyspraxia in Autism Spectrum Disorders [texte imprimé] / Matthew W. MOSCONI, Auteur ; Yukari TAKARAE, Auteur ; John A. SWEENEY, Auteur . - 2011 . - p.355-380. Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=139

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Neurophysiological hyperresponsivity to sensory input in autism spectrum disorders / Yukari TAKARAE in Journal of Neurodevelopmental Disorders, 8-1 (December 2016)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.29 Titre : Neurophysiological hyperresponsivity to sensory input in autism spectrum disorders Type de document : texte imprimé Auteurs : Yukari TAKARAE, Auteur ; Savanna R. SABLICH, Auteur ; Stormi P. WHITE, Auteur ; John A. SWEENEY, Auteur Article en page(s) : p.29 Langues : Anglais (eng) Mots-clés : Autism  Contrast sensitivity  Heterogeneity  Individual differences  Sensory hypersensitivity Index. décimale : PER Périodiques Résumé : BACKGROUND: Atypical sensory processing is a common clinical observation in autism spectrum disorder (ASD). Neural hyperexcitability has been suggested as the cause for sensory hypersensitivity, a frequently reported clinical observation in ASD. We examined visual evoked responses to parametric increases in stimulus contrast in order to model neural responsivity of sensory systems in ASD. METHODS: Thirteen high-functioning individuals with ASD and 12 typically developing (TD) individuals completed a steady-state visual evoked potential study. Stimuli were vertical circular gratings oscillating at 3.76 Hz at varying contrasts (5, 10, 20,..., 90 % contrast, 10 levels). The average spectral power at the stimulus oscillation frequency was calculated for each contrast level. RESULTS: The magnitude of evoked sensory responses increased at a significantly greater rate and resulted in disproportionately elevated activation with higher contrasts in the ASD group. Approximately 45 % of ASD participants had rates of response increases greater than any TD participant. This alteration was highly associated with parental reports of these participants' sensory difficulties. CONCLUSIONS: Greater increases in visual responses over contrast manipulation suggest heightened excitability in the sensory cortex in ASD participants. Heightened neural excitability was observed in a substantial portion but not all of the ASD participants. This pattern suggests that individuals with higher excitability may constitute a neurobiologically distinct subgroup requiring individualized treatment interventions. En ligne : http://dx.doi.org/10.1186/s11689-016-9162-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=349 [article] Neurophysiological hyperresponsivity to sensory input in autism spectrum disorders [texte imprimé] / Yukari TAKARAE, Auteur ; Savanna R. SABLICH, Auteur ; Stormi P. WHITE, Auteur ; John A. SWEENEY, Auteur . - p.29. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 8-1 (December 2016) . - p.29 Mots-clés : Autism  Contrast sensitivity  Heterogeneity  Individual differences  Sensory hypersensitivity Index. décimale : PER Périodiques Résumé : BACKGROUND: Atypical sensory processing is a common clinical observation in autism spectrum disorder (ASD). Neural hyperexcitability has been suggested as the cause for sensory hypersensitivity, a frequently reported clinical observation in ASD. We examined visual evoked responses to parametric increases in stimulus contrast in order to model neural responsivity of sensory systems in ASD. METHODS: Thirteen high-functioning individuals with ASD and 12 typically developing (TD) individuals completed a steady-state visual evoked potential study. Stimuli were vertical circular gratings oscillating at 3.76 Hz at varying contrasts (5, 10, 20,..., 90 % contrast, 10 levels). The average spectral power at the stimulus oscillation frequency was calculated for each contrast level. RESULTS: The magnitude of evoked sensory responses increased at a significantly greater rate and resulted in disproportionately elevated activation with higher contrasts in the ASD group. Approximately 45 % of ASD participants had rates of response increases greater than any TD participant. This alteration was highly associated with parental reports of these participants' sensory difficulties. CONCLUSIONS: Greater increases in visual responses over contrast manipulation suggest heightened excitability in the sensory cortex in ASD participants. Heightened neural excitability was observed in a substantial portion but not all of the ASD participants. This pattern suggests that individuals with higher excitability may constitute a neurobiologically distinct subgroup requiring individualized treatment interventions. En ligne : http://dx.doi.org/10.1186/s11689-016-9162-9 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=349

Resting state EEG abnormalities in autism spectrum disorders / Jing WANG in Journal of Neurodevelopmental Disorders, 5-1 (December 2013)  

Public ISBD [article]  inJournal of Neurodevelopmental Disorders > 5-1 (December 2013) . - p.24 Titre : Resting state EEG abnormalities in autism spectrum disorders Type de document : texte imprimé Auteurs : Jing WANG, Auteur ; Jamie BARSTEIN, Auteur ; Lauren E ETHRIDGE, Auteur ; Matthew W. MOSCONI, Auteur ; Yukari TAKARAE, Auteur ; John A. SWEENEY, Auteur Article en page(s) : p.24 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are a group of complex and heterogeneous developmental disorders involving multiple neural system dysfunctions. In an effort to understand neurophysiological substrates, identify etiopathophysiologically distinct subgroups of patients, and track outcomes of novel treatments with translational biomarkers, EEG (electroencephalography) studies offer a promising research strategy in ASD. Resting-state EEG studies of ASD suggest a U-shaped profile of electrophysiological power alterations, with excessive power in low-frequency and high-frequency bands, abnormal functional connectivity, and enhanced power in the left hemisphere of the brain. In this review, we provide a summary of recent findings, discuss limitations in available research that may contribute to inconsistencies in the literature, and offer suggestions for future research in this area for advancing the understanding of ASD. En ligne : http://dx.doi.org/10.1186/1866-1955-5-24 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=345 [article] Resting state EEG abnormalities in autism spectrum disorders [texte imprimé] / Jing WANG, Auteur ; Jamie BARSTEIN, Auteur ; Lauren E ETHRIDGE, Auteur ; Matthew W. MOSCONI, Auteur ; Yukari TAKARAE, Auteur ; John A. SWEENEY, Auteur . - p.24. Langues : Anglais (eng) in Journal of Neurodevelopmental Disorders > 5-1 (December 2013) . - p.24 Index. décimale : PER Périodiques Résumé : Autism spectrum disorders (ASD) are a group of complex and heterogeneous developmental disorders involving multiple neural system dysfunctions. In an effort to understand neurophysiological substrates, identify etiopathophysiologically distinct subgroups of patients, and track outcomes of novel treatments with translational biomarkers, EEG (electroencephalography) studies offer a promising research strategy in ASD. Resting-state EEG studies of ASD suggest a U-shaped profile of electrophysiological power alterations, with excessive power in low-frequency and high-frequency bands, abnormal functional connectivity, and enhanced power in the left hemisphere of the brain. In this review, we provide a summary of recent findings, discuss limitations in available research that may contribute to inconsistencies in the literature, and offer suggestions for future research in this area for advancing the understanding of ASD. En ligne : http://dx.doi.org/10.1186/1866-1955-5-24 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=345

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