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Détail de l'auteur
Auteur Harma MEFFERT |
Documents disponibles écrits par cet auteur (3)



Diagnosing Autism Spectrum Disorders in Adults: the Use of Autism Diagnostic Observation Schedule (ADOS) Module 4 / Jojanneke A. BASTIAANSEN in Journal of Autism and Developmental Disorders, 41-9 (September 2011)
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[article]
Titre : Diagnosing Autism Spectrum Disorders in Adults: the Use of Autism Diagnostic Observation Schedule (ADOS) Module 4 Type de document : Texte imprimé et/ou numérique Auteurs : Jojanneke A. BASTIAANSEN, Auteur ; Harma MEFFERT, Auteur ; Simone HEIN, Auteur ; Petra HUIZINGA, Auteur ; Cees KETELAARS, Auteur ; Marieke PIJNENBORG, Auteur ; Arnold BARTELS, Auteur ; Ruud B. MINDERAA, Auteur ; Christian KEYSERS, Auteur ; Annelies A. DE BILDT, Auteur Année de publication : 2011 Article en page(s) : p.1256-1266 Langues : Anglais (eng) Mots-clés : Autism Adults ADOS Diagnosis Schizophrenia Psychopathy Index. décimale : PER Périodiques Résumé : Autism Diagnostic Observation Schedule (ADOS) module 4 was investigated in an independent sample of high-functioning adult males with an autism spectrum disorder (ASD) compared to three specific diagnostic groups: schizophrenia, psychopathy, and typical development. ADOS module 4 proves to be a reliable instrument with good predictive value. It can adequately discriminate ASD from psychopathy and typical development, but is less specific with respect to schizophrenia due to behavioral overlap between autistic and negative symptoms. However, these groups differ on some core items and explorative analyses indicate that a revision of the algorithm in line with Gotham et al. (J Autism Dev Disord 37: 613–627, 2007) could be beneficial for discriminating ASD from schizophrenia. En ligne : http://dx.doi.org/10.1007/s10803-010-1157-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=142
in Journal of Autism and Developmental Disorders > 41-9 (September 2011) . - p.1256-1266[article] Diagnosing Autism Spectrum Disorders in Adults: the Use of Autism Diagnostic Observation Schedule (ADOS) Module 4 [Texte imprimé et/ou numérique] / Jojanneke A. BASTIAANSEN, Auteur ; Harma MEFFERT, Auteur ; Simone HEIN, Auteur ; Petra HUIZINGA, Auteur ; Cees KETELAARS, Auteur ; Marieke PIJNENBORG, Auteur ; Arnold BARTELS, Auteur ; Ruud B. MINDERAA, Auteur ; Christian KEYSERS, Auteur ; Annelies A. DE BILDT, Auteur . - 2011 . - p.1256-1266.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 41-9 (September 2011) . - p.1256-1266
Mots-clés : Autism Adults ADOS Diagnosis Schizophrenia Psychopathy Index. décimale : PER Périodiques Résumé : Autism Diagnostic Observation Schedule (ADOS) module 4 was investigated in an independent sample of high-functioning adult males with an autism spectrum disorder (ASD) compared to three specific diagnostic groups: schizophrenia, psychopathy, and typical development. ADOS module 4 proves to be a reliable instrument with good predictive value. It can adequately discriminate ASD from psychopathy and typical development, but is less specific with respect to schizophrenia due to behavioral overlap between autistic and negative symptoms. However, these groups differ on some core items and explorative analyses indicate that a revision of the algorithm in line with Gotham et al. (J Autism Dev Disord 37: 613–627, 2007) could be beneficial for discriminating ASD from schizophrenia. En ligne : http://dx.doi.org/10.1007/s10803-010-1157-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=142 Dysfunctional representation of expected value is associated with reinforcement-based decision-making deficits in adolescents with conduct problems / Stuart F. WHITE in Journal of Child Psychology and Psychiatry, 57-8 (August 2016)
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Titre : Dysfunctional representation of expected value is associated with reinforcement-based decision-making deficits in adolescents with conduct problems Type de document : Texte imprimé et/ou numérique Auteurs : Stuart F. WHITE, Auteur ; Patrick M. TYLER, Auteur ; Anna K. ERWAY, Auteur ; Mary L. BOTKIN, Auteur ; Venkata KOLLI, Auteur ; Harma MEFFERT, Auteur ; Kayla POPE, Auteur ; James R. BLAIR, Auteur Article en page(s) : p.938-946 Langues : Anglais (eng) Mots-clés : Conduct problems decision-making anterior insula expected value prediction error Index. décimale : PER Périodiques Résumé : Background Previous work has shown that patients with conduct problems (CP) show impairments in reinforcement-based decision-making. However, studies with patients have not previously demonstrated any relationships between impairment in any of the neurocomputations underpinning reinforcement-based decision-making and specific symptom sets [e.g. level of CP and/or callous-unemotional (CU) traits]. Methods Seventy-two youths [20 female, mean age = 13.81 (SD = 2.14), mean IQ = 102.34 (SD = 10.99)] from a residential treatment program and the community completed a passive avoidance task while undergoing functional MRI. Results Greater levels of CP were associated with poorer task performance. Reduced representation of expected values (EV) when making avoidance responses within bilateral anterior insula cortex/inferior frontal gyrus (AIC/iFG) and striatum was associated with greater levels of CP but not CU traits. Conclusions The current data indicate that difficulties in the use of value information to motivate decisions to avoid suboptimal choices are associated with increased levels of CP (though not severity of CU traits). Moreover, they account for the behavioral deficits observed during reinforcement-based decision-making in youth with CP. In short, an individual's relative failure to utilize value information within AIC/iFG to avoid bad choices is associated with elevated levels of CP. En ligne : http://dx.doi.org/10.1111/jcpp.12557 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292
in Journal of Child Psychology and Psychiatry > 57-8 (August 2016) . - p.938-946[article] Dysfunctional representation of expected value is associated with reinforcement-based decision-making deficits in adolescents with conduct problems [Texte imprimé et/ou numérique] / Stuart F. WHITE, Auteur ; Patrick M. TYLER, Auteur ; Anna K. ERWAY, Auteur ; Mary L. BOTKIN, Auteur ; Venkata KOLLI, Auteur ; Harma MEFFERT, Auteur ; Kayla POPE, Auteur ; James R. BLAIR, Auteur . - p.938-946.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 57-8 (August 2016) . - p.938-946
Mots-clés : Conduct problems decision-making anterior insula expected value prediction error Index. décimale : PER Périodiques Résumé : Background Previous work has shown that patients with conduct problems (CP) show impairments in reinforcement-based decision-making. However, studies with patients have not previously demonstrated any relationships between impairment in any of the neurocomputations underpinning reinforcement-based decision-making and specific symptom sets [e.g. level of CP and/or callous-unemotional (CU) traits]. Methods Seventy-two youths [20 female, mean age = 13.81 (SD = 2.14), mean IQ = 102.34 (SD = 10.99)] from a residential treatment program and the community completed a passive avoidance task while undergoing functional MRI. Results Greater levels of CP were associated with poorer task performance. Reduced representation of expected values (EV) when making avoidance responses within bilateral anterior insula cortex/inferior frontal gyrus (AIC/iFG) and striatum was associated with greater levels of CP but not CU traits. Conclusions The current data indicate that difficulties in the use of value information to motivate decisions to avoid suboptimal choices are associated with increased levels of CP (though not severity of CU traits). Moreover, they account for the behavioral deficits observed during reinforcement-based decision-making in youth with CP. In short, an individual's relative failure to utilize value information within AIC/iFG to avoid bad choices is associated with elevated levels of CP. En ligne : http://dx.doi.org/10.1111/jcpp.12557 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=292 The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (n = 93) / Annelies A. DE BILDT in Journal of Autism and Developmental Disorders, 46-1 (January 2016)
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Titre : The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (n = 93) Type de document : Texte imprimé et/ou numérique Auteurs : Annelies A. DE BILDT, Auteur ; Sjoerd SYTEMA, Auteur ; Harma MEFFERT, Auteur ; Jojanneke A. BASTIAANSEN, Auteur Année de publication : 2016 Article en page(s) : p.21-30 Langues : Anglais (eng) Mots-clés : Autism Spectrum Disorder Schizophrenia Psychopathy Assessment Classification Adults Index. décimale : PER Périodiques Résumé : This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in J Autism Dev Disord 44(8):1996–2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off resembled the original algorithm ASD cut-off: highly specific for psychopathy and controls, lower sensitivity than Hus and Lord (2014; i.e. ASD .61, AD .53). The revised algorithm AD cut-off improved sensitivity over the original algorithm. Discriminating ASD from schizophrenia was still challenging, but the better-balanced sensitivity (.53) and specificity (.78) of the revised algorithm AD cut-off may aide clinicians’ differential diagnosis. Findings support using the revised algorithm, being conceptually conform the other modules, thus improving comparability across the lifespan. En ligne : http://dx.doi.org/10.1007/s10803-015-2532-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278
in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.21-30[article] The Autism Diagnostic Observation Schedule, Module 4: Application of the Revised Algorithms in an Independent, Well-Defined, Dutch Sample (n = 93) [Texte imprimé et/ou numérique] / Annelies A. DE BILDT, Auteur ; Sjoerd SYTEMA, Auteur ; Harma MEFFERT, Auteur ; Jojanneke A. BASTIAANSEN, Auteur . - 2016 . - p.21-30.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-1 (January 2016) . - p.21-30
Mots-clés : Autism Spectrum Disorder Schizophrenia Psychopathy Assessment Classification Adults Index. décimale : PER Périodiques Résumé : This study examined the discriminative ability of the revised Autism Diagnostic Observation Schedule module 4 algorithm (Hus and Lord in J Autism Dev Disord 44(8):1996–2012, 2014) in 93 Dutch males with Autism Spectrum Disorder (ASD), schizophrenia, psychopathy or controls. Discriminative ability of the revised algorithm ASD cut-off resembled the original algorithm ASD cut-off: highly specific for psychopathy and controls, lower sensitivity than Hus and Lord (2014; i.e. ASD .61, AD .53). The revised algorithm AD cut-off improved sensitivity over the original algorithm. Discriminating ASD from schizophrenia was still challenging, but the better-balanced sensitivity (.53) and specificity (.78) of the revised algorithm AD cut-off may aide clinicians’ differential diagnosis. Findings support using the revised algorithm, being conceptually conform the other modules, thus improving comparability across the lifespan. En ligne : http://dx.doi.org/10.1007/s10803-015-2532-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278