Lack of Correlation Between Metallic Elements Analyzed in Hair by ICP-MS and Autism / Giuseppe DE PALMA in Journal of Autism and Developmental Disorders, 42-3 (March 2012)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 42-3 (March 2012) . - p.342-353 Titre : Lack of Correlation Between Metallic Elements Analyzed in Hair by ICP-MS and Autism Type de document : Texte imprimé et/ou numérique Auteurs : Giuseppe DE PALMA, Auteur ; Simona CATALANI, Auteur ; Anna FRANCO, Auteur ; Maurizio BRIGHENTI, Auteur ; Pietro APOSTOLI, Auteur Année de publication : 2012 Article en page(s) : p.342-353 Langues : Anglais (eng) Mots-clés : Autism  Hair  Metallic elements  Inductively coupled mass spectrometry Index. décimale : PER Périodiques Résumé : A cross-sectional case–control study was carried out to evaluate the concentrations of metallic elements in the hair of 44 children with diagnosis of autism and 61 age-balanced controls. Unadjusted comparisons showed higher concentrations of molybdenum, lithium and selenium in autistic children. Logistic regression analysis confirmed the role of risk factor for male gender and showed a slight association with molybdenum concentrations. Unconventional chelation and vitamin-mineral supplementation were ineffective on elemental hair concentrations. A meta-analysis including the present and previous similar studies excluded any association of autism with hair concentrations of mercury, cadmium, selenium, lithium and copper. A slight association was found for lead only, but it was very weak, as strictly dependent on the worst data from one study. En ligne : http://dx.doi.org/10.1007/s10803-011-1245-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152 [article] Lack of Correlation Between Metallic Elements Analyzed in Hair by ICP-MS and Autism [Texte imprimé et/ou numérique] / Giuseppe DE PALMA, Auteur ; Simona CATALANI, Auteur ; Anna FRANCO, Auteur ; Maurizio BRIGHENTI, Auteur ; Pietro APOSTOLI, Auteur . - 2012 . - p.342-353. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 42-3 (March 2012) . - p.342-353 Mots-clés : Autism  Hair  Metallic elements  Inductively coupled mass spectrometry Index. décimale : PER Périodiques Résumé : A cross-sectional case–control study was carried out to evaluate the concentrations of metallic elements in the hair of 44 children with diagnosis of autism and 61 age-balanced controls. Unadjusted comparisons showed higher concentrations of molybdenum, lithium and selenium in autistic children. Logistic regression analysis confirmed the role of risk factor for male gender and showed a slight association with molybdenum concentrations. Unconventional chelation and vitamin-mineral supplementation were ineffective on elemental hair concentrations. A meta-analysis including the present and previous similar studies excluded any association of autism with hair concentrations of mercury, cadmium, selenium, lithium and copper. A slight association was found for lead only, but it was very weak, as strictly dependent on the worst data from one study. En ligne : http://dx.doi.org/10.1007/s10803-011-1245-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=152

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