[article] 
inJournal of Child Psychology and Psychiatry > 55-3 (March 2014) . - p.201-203

Titre :	Editorial: Illuminating the dark matter of developmental neuropsychiatric genetics – strategic focus for future research in child psychology and psychiatry
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Klaus-Peter LESCH, Auteur
Article en page(s) :	p.201-203
Langues :	Anglais (eng)
Mots-clés :	Behavioural genetics  neuropsychiatric genetics  gene-by-environment interaction  epigenetics  neurodevelopmental impairments  gene-trait/disorder association studies  guidelines
Index. décimale :	PER Périodiques
Résumé :	Research on genetic factors influencing cognitive and behavioural traits or which are central to the aetiology of neuropsychiatric diseases has been complicated by a furtive discrepancy between high heritability estimates and a scarcity of replicable gene-disorder associations. This ‘missing heritability’ has been either euphemised as the ‘dark matter’ of gene-trait association or aggravated as the ‘looming crisis in behavioural genetics’. Nevertheless, in recognising the importance of this topic for our understanding of child psychiatric conditions and highlighting its commitment to the field, the Journal of Child Psychology and Psychiatry (JCPP) has for the first time appointed an editor with special responsibility for molecular (epi)genetics.
En ligne :	http://dx.doi.org/10.1111/jcpp.12223
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=226

[article] Editorial: Illuminating the dark matter of developmental neuropsychiatric genetics – strategic focus for future research in child psychology and psychiatry [Texte imprimé et/ou numérique] / Klaus-Peter LESCH, Auteur . - p.201-203.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 55-3 (March 2014) . - p.201-203

Mots-clés :	Behavioural genetics  neuropsychiatric genetics  gene-by-environment interaction  epigenetics  neurodevelopmental impairments  gene-trait/disorder association studies  guidelines
Index. décimale :	PER Périodiques
Résumé :	Research on genetic factors influencing cognitive and behavioural traits or which are central to the aetiology of neuropsychiatric diseases has been complicated by a furtive discrepancy between high heritability estimates and a scarcity of replicable gene-disorder associations. This ‘missing heritability’ has been either euphemised as the ‘dark matter’ of gene-trait association or aggravated as the ‘looming crisis in behavioural genetics’. Nevertheless, in recognising the importance of this topic for our understanding of child psychiatric conditions and highlighting its commitment to the field, the Journal of Child Psychology and Psychiatry (JCPP) has for the first time appointed an editor with special responsibility for molecular (epi)genetics.
En ligne :	http://dx.doi.org/10.1111/jcpp.12223
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=226