Autistic Spectrum Disorders in Velo-cardio Facial Syndrome (22q11.2 Deletion) / Kevin M. ANTSHEL in Journal of Autism and Developmental Disorders, 37-9 (October 2007)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 37-9 (October 2007) . - p.1776-1786 Titre : Autistic Spectrum Disorders in Velo-cardio Facial Syndrome (22q11.2 Deletion) Type de document : Texte imprimé et/ou numérique Auteurs : Kevin M. ANTSHEL, Auteur ; Robert J. SHPRINTZEN, Auteur ; Anne Marie HIGGINS, Auteur ; Nuria ABDULSABUR, Auteur ; Wanda P. FREMONT, Auteur ; Jena PEEBLES, Auteur ; Leslie STRUNGE, Auteur ; Alka ANEJA, Auteur ; Kimberly STALLONE, Auteur ; Wendy R. KATES, Auteur Année de publication : 2007 Article en page(s) : p.1776-1786 Langues : Anglais (eng) Mots-clés : Velocardiofacial-syndrome 22q11.2-deletion Autism-spectrum-disorder Amygdala Index. décimale : PER Périodiques Résumé : The extent to which the phenotype of children comorbid for velocardiofacial syndrome (VCFS) and autism spectrum disorders (ASD) differs from that of VCFS-only has not been studied. The sample consisted of 41 children (20 females) with VCFS, ranging in age from 6.5 years to 15.8 years. Eight children with VCFS met formal DSM-IV diagnostic criteria for autism based upon the ADI-R. These eight plus an additional nine participants met diagnostic criteria for an autistic spectrum disorder (VCFS + ASD). Ninety-four percent of the children with VCFS + ASD had a co-occurring psychiatric disorder while 60% of children with VCFS had a psychiatric disorder. Children with VCFS + ASD had larger right amygdala volumes. All other neuroanatomic regions of interest were statistically similar between the two groups. En ligne : http://dx.doi.org/10.1007/s10803-006-0308-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=175 [article] Autistic Spectrum Disorders in Velo-cardio Facial Syndrome (22q11.2 Deletion) [Texte imprimé et/ou numérique] / Kevin M. ANTSHEL, Auteur ; Robert J. SHPRINTZEN, Auteur ; Anne Marie HIGGINS, Auteur ; Nuria ABDULSABUR, Auteur ; Wanda P. FREMONT, Auteur ; Jena PEEBLES, Auteur ; Leslie STRUNGE, Auteur ; Alka ANEJA, Auteur ; Kimberly STALLONE, Auteur ; Wendy R. KATES, Auteur . - 2007 . - p.1776-1786. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 37-9 (October 2007) . - p.1776-1786 Mots-clés : Velocardiofacial-syndrome 22q11.2-deletion Autism-spectrum-disorder Amygdala Index. décimale : PER Périodiques Résumé : The extent to which the phenotype of children comorbid for velocardiofacial syndrome (VCFS) and autism spectrum disorders (ASD) differs from that of VCFS-only has not been studied. The sample consisted of 41 children (20 females) with VCFS, ranging in age from 6.5 years to 15.8 years. Eight children with VCFS met formal DSM-IV diagnostic criteria for autism based upon the ADI-R. These eight plus an additional nine participants met diagnostic criteria for an autistic spectrum disorder (VCFS + ASD). Ninety-four percent of the children with VCFS + ASD had a co-occurring psychiatric disorder while 60% of children with VCFS had a psychiatric disorder. Children with VCFS + ASD had larger right amygdala volumes. All other neuroanatomic regions of interest were statistically similar between the two groups. En ligne : http://dx.doi.org/10.1007/s10803-006-0308-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=175

Is attention deficit hyperactivity disorder a valid diagnosis in the presence of high IQ? Results from the MGH Longitudinal Family Studies of ADHD / Kevin M. ANTSHEL in Journal of Child Psychology and Psychiatry, 48-7 (July 2007)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 48-7 (July 2007) . - p.687–694 Titre : Is attention deficit hyperactivity disorder a valid diagnosis in the presence of high IQ? Results from the MGH Longitudinal Family Studies of ADHD Type de document : Texte imprimé et/ou numérique Auteurs : Kevin M. ANTSHEL, Auteur ; Joseph BIEDERMAN, Auteur ; Stephen V. FARAONE, Auteur ; Kimberly STALLONE, Auteur ; Andrea NAVE, Auteur ; Felice A. KAUFMANN, Auteur ; Alysa DOYLE, Auteur ; Ronna FRIED, Auteur ; Larry SEIDMAN, Auteur Année de publication : 2007 Article en page(s) : p.687–694 Langues : Anglais (eng) Mots-clés : intelligence ADD/ADHD gifted diagnosis diagnostic-validity Index. décimale : PER Périodiques Résumé : Background: The aim of this study was to assess the validity of diagnosing attention deficit/hyperactivity disorder (ADHD) in high IQ children and to further characterize the clinical features associated with their ADHD. Methods: We operationalized giftedness/high IQ as having a full scale IQ ≥120. We identified 92 children with a high IQ who did not have ADHD and 49 children with a high IQ that met diagnostic criteria for ADHD who had participated in the Massachusetts General Hospital Longitudinal Family Studies of ADHD. Results: Of our participants with ADHD and a high IQ, the majority (n = 35) met criteria for the Combined subtype. Relative to control participants, children with ADHD and high IQ had a higher prevalence rate of familial ADHD in first-degree relatives, repeated grades more often, had a poorer performance on the WISC-III Block Design, had more comorbid psychopathology, and had more functional impairments across a number of domains. Conclusions: Children with a high IQ and ADHD showed a pattern of familiality as well as cognitive, psychiatric and behavioral features consistent with the diagnosis of ADHD in children with average IQ. These data suggest that the diagnosis of ADHD is valid among high IQ children. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01735.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=142 [article] Is attention deficit hyperactivity disorder a valid diagnosis in the presence of high IQ? Results from the MGH Longitudinal Family Studies of ADHD [Texte imprimé et/ou numérique] / Kevin M. ANTSHEL, Auteur ; Joseph BIEDERMAN, Auteur ; Stephen V. FARAONE, Auteur ; Kimberly STALLONE, Auteur ; Andrea NAVE, Auteur ; Felice A. KAUFMANN, Auteur ; Alysa DOYLE, Auteur ; Ronna FRIED, Auteur ; Larry SEIDMAN, Auteur . - 2007 . - p.687–694. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 48-7 (July 2007) . - p.687–694 Mots-clés : intelligence ADD/ADHD gifted diagnosis diagnostic-validity Index. décimale : PER Périodiques Résumé : Background: The aim of this study was to assess the validity of diagnosing attention deficit/hyperactivity disorder (ADHD) in high IQ children and to further characterize the clinical features associated with their ADHD. Methods: We operationalized giftedness/high IQ as having a full scale IQ ≥120. We identified 92 children with a high IQ who did not have ADHD and 49 children with a high IQ that met diagnostic criteria for ADHD who had participated in the Massachusetts General Hospital Longitudinal Family Studies of ADHD. Results: Of our participants with ADHD and a high IQ, the majority (n = 35) met criteria for the Combined subtype. Relative to control participants, children with ADHD and high IQ had a higher prevalence rate of familial ADHD in first-degree relatives, repeated grades more often, had a poorer performance on the WISC-III Block Design, had more comorbid psychopathology, and had more functional impairments across a number of domains. Conclusions: Children with a high IQ and ADHD showed a pattern of familiality as well as cognitive, psychiatric and behavioral features consistent with the diagnosis of ADHD in children with average IQ. These data suggest that the diagnosis of ADHD is valid among high IQ children. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2007.01735.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=142

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