[article] 
inJournal of Autism and Developmental Disorders > 46-2 (February 2016) . - p.534-543

Titre :	Relationship of the Acoustic Startle Response and Its Modulation to Emotional and Behavioral Problems in Typical Development Children and Those with Autism Spectrum Disorders
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Hidetoshi TAKAHASHI, Auteur ; Sahoko KOMATSU, Auteur ; Takayuki NAKAHACHI, Auteur ; Kazuo OGINO, Auteur ; Yoko KAMIO, Auteur
Année de publication :	2016
Article en page(s) :	p.534-543
Langues :	Anglais (eng)
Mots-clés :	Autism spectrum disorders  Acoustic startle response  Prepulse inhibition  Sensory-motor gating  Habituation  Startle latency
Index. décimale :	PER Périodiques
Résumé :	Auditory hyper-reactivity is a common sensory-perceptual abnormality in autism spectrum disorders (ASD), which interrupts behavioral adaptation. We investigated acoustic startle response (ASR) modulations in 17 children with ASD and 27 with typical development (TD). Compared to TD, children with ASD had larger ASR magnitude to weak stimuli and more prolonged peak startle-latency. We could not find significant difference of prepulse inhibition (PPI) or habituation in ASD children compared to TD. However, habituation and PPI at 70-dB prepulses were negatively related to several subscales of Social Responsiveness Scale and the Strengths and Difficulties Questionnaire, when considering all children. Comprehensive investigation of ASR and its modulation might increase understanding of the neurophysiological impairments underlying ASD and other mental health problems in children.
En ligne :	http://dx.doi.org/10.1007/s10803-015-2593-4
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280

[article] Relationship of the Acoustic Startle Response and Its Modulation to Emotional and Behavioral Problems in Typical Development Children and Those with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Hidetoshi TAKAHASHI, Auteur ; Sahoko KOMATSU, Auteur ; Takayuki NAKAHACHI, Auteur ; Kazuo OGINO, Auteur ; Yoko KAMIO, Auteur . - 2016 . - p.534-543.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 46-2 (February 2016) . - p.534-543

Mots-clés :	Autism spectrum disorders  Acoustic startle response  Prepulse inhibition  Sensory-motor gating  Habituation  Startle latency
Index. décimale :	PER Périodiques
Résumé :	Auditory hyper-reactivity is a common sensory-perceptual abnormality in autism spectrum disorders (ASD), which interrupts behavioral adaptation. We investigated acoustic startle response (ASR) modulations in 17 children with ASD and 27 with typical development (TD). Compared to TD, children with ASD had larger ASR magnitude to weak stimuli and more prolonged peak startle-latency. We could not find significant difference of prepulse inhibition (PPI) or habituation in ASD children compared to TD. However, habituation and PPI at 70-dB prepulses were negatively related to several subscales of Social Responsiveness Scale and the Strengths and Difficulties Questionnaire, when considering all children. Comprehensive investigation of ASR and its modulation might increase understanding of the neurophysiological impairments underlying ASD and other mental health problems in children.
En ligne :	http://dx.doi.org/10.1007/s10803-015-2593-4
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=280