Shared familial transmission of autism spectrum and attention-deficit/hyperactivity disorders / Erica D. MUSSER in Journal of Child Psychology and Psychiatry, 55-7 (July 2014)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 55-7 (July 2014) . - p.819-827 Titre : Shared familial transmission of autism spectrum and attention-deficit/hyperactivity disorders Type de document : Texte imprimé et/ou numérique Auteurs : Erica D. MUSSER, Auteur ; Elizabeth HAWKEY, Auteur ; Svetlana S. KACHAN-LIU, Auteur ; Paul LEES, Auteur ; Jean-Baptiste ROULLET, Auteur ; Katrina GODDARD, Auteur ; Robert D. STEINER, Auteur ; Joel T. NIGG, Auteur Article en page(s) : p.819-827 Langues : Anglais (eng) Mots-clés : Attention-deficit/hyperactivity disorder  autism spectrum disorder  shared familial transmission Index. décimale : PER Périodiques Résumé : Background To determine whether familial transmission is shared between autism spectrum disorders and attention-deficit/hyperactivity disorder, we assessed the prevalence, rates of comorbidity, and familial transmission of both disorders in a large population-based sample of children during a recent 7 year period. Methods Study participants included all children born to parents with the Kaiser Permanente Northwest (KPNW) Health Plan between 1 January 1998 and 31 December 2004 (n = 35,073). Children and mothers with physician-identified autism spectrum disorders (ASD) and/or attention-deficit/hyperactivity disorder (ADHD) were identified via electronic medical records maintained for all KPNW members. Results Among children aged 6–12 years, prevalence was 2.0% for ADHD and 0.8% for ASD; within those groups, 0.2% of the full sample (19% of the ASD sample and 9.6% of the ADHD sample) had co-occurring ASD and ADHD, when all children were included. When mothers had a diagnosis of ADHD, first born offspring were at 6-fold risk of ADHD alone (OR = 5.02, p .0001) and at 2.5-fold risk of ASD alone (OR = 2.52, p .01). Results were not accounted for by maternal age, child gestational age, child gender, and child race. Conclusions Autism spectrum disorders shares familial transmission with ADHD. ADHD and ASD have a partially overlapping diathesis. En ligne : http://dx.doi.org/10.1111/jcpp.12201 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=235 [article] Shared familial transmission of autism spectrum and attention-deficit/hyperactivity disorders [Texte imprimé et/ou numérique] / Erica D. MUSSER, Auteur ; Elizabeth HAWKEY, Auteur ; Svetlana S. KACHAN-LIU, Auteur ; Paul LEES, Auteur ; Jean-Baptiste ROULLET, Auteur ; Katrina GODDARD, Auteur ; Robert D. STEINER, Auteur ; Joel T. NIGG, Auteur . - p.819-827. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 55-7 (July 2014) . - p.819-827 Mots-clés : Attention-deficit/hyperactivity disorder  autism spectrum disorder  shared familial transmission Index. décimale : PER Périodiques Résumé : Background To determine whether familial transmission is shared between autism spectrum disorders and attention-deficit/hyperactivity disorder, we assessed the prevalence, rates of comorbidity, and familial transmission of both disorders in a large population-based sample of children during a recent 7 year period. Methods Study participants included all children born to parents with the Kaiser Permanente Northwest (KPNW) Health Plan between 1 January 1998 and 31 December 2004 (n = 35,073). Children and mothers with physician-identified autism spectrum disorders (ASD) and/or attention-deficit/hyperactivity disorder (ADHD) were identified via electronic medical records maintained for all KPNW members. Results Among children aged 6–12 years, prevalence was 2.0% for ADHD and 0.8% for ASD; within those groups, 0.2% of the full sample (19% of the ASD sample and 9.6% of the ADHD sample) had co-occurring ASD and ADHD, when all children were included. When mothers had a diagnosis of ADHD, first born offspring were at 6-fold risk of ADHD alone (OR = 5.02, p .0001) and at 2.5-fold risk of ASD alone (OR = 2.52, p .01). Results were not accounted for by maternal age, child gestational age, child gender, and child race. Conclusions Autism spectrum disorders shares familial transmission with ADHD. ADHD and ASD have a partially overlapping diathesis. En ligne : http://dx.doi.org/10.1111/jcpp.12201 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=235

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