[article] 
inJournal of Autism and Developmental Disorders > 47-6 (June 2017) . - p.1628-1644

Titre :	Autism Spectrum Disorder Symptoms in Infants with Fragile X Syndrome: A Prospective Case Series
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Abigail L. HOGAN, Auteur ; Kelly E. CARAVELLA, Auteur ; Jordan EZELL, Auteur ; Lisa RAGUE, Auteur ; Kimberly HILLS, Auteur ; Jane E. ROBERTS, Auteur
Article en page(s) :	p.1628-1644
Langues :	Anglais (eng)
Mots-clés :	Fragile X syndrome  Autism spectrum disorder  Infants  Case studies
Index. décimale :	PER Périodiques
Résumé :	No studies to date have prospectively examined early autism spectrum disorder (ASD) markers in infants with fragile X syndrome (FXS), who are at elevated risk for ASD. This paper describes the developmental profiles of eight infants with FXS from 9 to 24 months of age. Four meet diagnostic criteria for ASD at 24 months of age, and four do not. Trends in these case studies suggest that early social-communicative deficits differentiate infants with and without later ASD diagnoses in ways that are similar to later-born siblings of children with ASD. Repetitive behaviors and cognitive and adaptive impairments are present in all FXS infants throughout development, suggesting that these deficits reflect the general FXS phenotype and not ASD in FXS specifically.
En ligne :	http://dx.doi.org/10.1007/s10803-017-3081-9
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=308

[article] Autism Spectrum Disorder Symptoms in Infants with Fragile X Syndrome: A Prospective Case Series [Texte imprimé et/ou numérique] / Abigail L. HOGAN, Auteur ; Kelly E. CARAVELLA, Auteur ; Jordan EZELL, Auteur ; Lisa RAGUE, Auteur ; Kimberly HILLS, Auteur ; Jane E. ROBERTS, Auteur . - p.1628-1644.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 47-6 (June 2017) . - p.1628-1644

Mots-clés :	Fragile X syndrome  Autism spectrum disorder  Infants  Case studies
Index. décimale :	PER Périodiques
Résumé :	No studies to date have prospectively examined early autism spectrum disorder (ASD) markers in infants with fragile X syndrome (FXS), who are at elevated risk for ASD. This paper describes the developmental profiles of eight infants with FXS from 9 to 24 months of age. Four meet diagnostic criteria for ASD at 24 months of age, and four do not. Trends in these case studies suggest that early social-communicative deficits differentiate infants with and without later ASD diagnoses in ways that are similar to later-born siblings of children with ASD. Repetitive behaviors and cognitive and adaptive impairments are present in all FXS infants throughout development, suggesting that these deficits reflect the general FXS phenotype and not ASD in FXS specifically.
En ligne :	http://dx.doi.org/10.1007/s10803-017-3081-9
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=308