Genetic covariance between psychopathic traits and anticipatory skin conductance responses to threat: Evidence for a potential endophenotype / Pan WANG in Development and Psychopathology, 27-4 (Part 1) (November 2015)  

Public ISBD [article]  inDevelopment and Psychopathology > 27-4 (Part 1) (November 2015) . - p.1313-1322 Titre : Genetic covariance between psychopathic traits and anticipatory skin conductance responses to threat: Evidence for a potential endophenotype Type de document : Texte imprimé et/ou numérique Auteurs : Pan WANG, Auteur ; Yu GAO, Auteur ; Joshua ISEN, Auteur ; Catherine TUVBLAD, Auteur ; Adrian RAINE, Auteur ; Laura A. BAKER, Auteur Année de publication : 2015 Article en page(s) : p.1313-1322 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The genetic architecture of the association between psychopathic traits and reduced skin conductance responses (SCRs) is poorly understood. By using 752 twins aged 9–10 years, this study investigated the heritability of two SCR measures (anticipatory SCRs to impending aversive stimuli and unconditioned SCRs to the aversive stimuli themselves) in a countdown task. The study also investigated the genetic and environmental sources of the covariance between these SCR measures and two psychopathic personality traits: impulsive/disinhibited (reflecting impulsive–antisocial tendencies) and manipulative/deceitful (reflecting the affective–interpersonal features). For anticipatory SCRs, 27%, 14%, and 59% of the variation was due to genetic, shared environmental, and nonshared environmental effects, respectively, while the percentages for unconditioned SCRs were 44%, 2%, and 54%. The manipulative/deceitful (not impulsive/disinhibited) traits were negatively associated with both anticipatory SCRs (r = –.14, p < .05) and unconditioned SCRs (r = –.17, p < .05) in males only, with the former association significantly accounted for by genetic influences (rg = –.72). Reduced anticipatory SCRs represent a candidate endophenotype for the affective–interpersonal facets of psychopathic traits in males. En ligne : http://dx.doi.org/10.1017/S0954579414001424 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268 [article] Genetic covariance between psychopathic traits and anticipatory skin conductance responses to threat: Evidence for a potential endophenotype [Texte imprimé et/ou numérique] / Pan WANG, Auteur ; Yu GAO, Auteur ; Joshua ISEN, Auteur ; Catherine TUVBLAD, Auteur ; Adrian RAINE, Auteur ; Laura A. BAKER, Auteur . - 2015 . - p.1313-1322. Langues : Anglais (eng) in Development and Psychopathology > 27-4 (Part 1) (November 2015) . - p.1313-1322 Index. décimale : PER Périodiques Résumé : The genetic architecture of the association between psychopathic traits and reduced skin conductance responses (SCRs) is poorly understood. By using 752 twins aged 9–10 years, this study investigated the heritability of two SCR measures (anticipatory SCRs to impending aversive stimuli and unconditioned SCRs to the aversive stimuli themselves) in a countdown task. The study also investigated the genetic and environmental sources of the covariance between these SCR measures and two psychopathic personality traits: impulsive/disinhibited (reflecting impulsive–antisocial tendencies) and manipulative/deceitful (reflecting the affective–interpersonal features). For anticipatory SCRs, 27%, 14%, and 59% of the variation was due to genetic, shared environmental, and nonshared environmental effects, respectively, while the percentages for unconditioned SCRs were 44%, 2%, and 54%. The manipulative/deceitful (not impulsive/disinhibited) traits were negatively associated with both anticipatory SCRs (r = –.14, p < .05) and unconditioned SCRs (r = –.17, p < .05) in males only, with the former association significantly accounted for by genetic influences (rg = –.72). Reduced anticipatory SCRs represent a candidate endophenotype for the affective–interpersonal facets of psychopathic traits in males. En ligne : http://dx.doi.org/10.1017/S0954579414001424 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=268

Psychopathic personality development from ages 9 to 18: Genes and environment / Catherine TUVBLAD in Development and Psychopathology, 28-1 (February 2016)  

Public ISBD [article]  inDevelopment and Psychopathology > 28-1 (February 2016) . - p.27-44 Titre : Psychopathic personality development from ages 9 to 18: Genes and environment Type de document : Texte imprimé et/ou numérique Auteurs : Catherine TUVBLAD, Auteur ; Pan WANG, Auteur ; Serena BEZDJIAN, Auteur ; Adrian RAINE, Auteur ; Laura A. BAKER, Auteur Article en page(s) : p.27-44 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The genetic and environmental etiology of individual differences was examined in initial level and change in psychopathic personality from ages 9 to 18 years. A piecewise growth curve model, in which the first change score (G1) influenced all ages (9–10, 11–13, 14–15, and 16–18 years) and the second change score (G2) only influenced ages 14–15 and 16–18 years, fit the data better did than the standard single slope model, suggesting a turning point from childhood to adolescence. The results indicated that variations in levels and both change scores were mainly due to genetic (A) and nonshared environmental (E) influences (i.e., AE structure for G0, G1, and G2). No sex differences were found except on the mean values of level and change scores. Based on caregiver ratings, about 81% of variance in G0, 89% of variance in G1, and 94% of variance in G2 were explained by genetic factors, whereas for youth self-reports, these three proportions were 94%, 71%, and 66%, respectively. The larger contribution of genetic variance and covariance in caregiver ratings than in youth self-reports may suggest that caregivers considered the changes in their children to be more similar as compared to how the children viewed themselves. En ligne : http://dx.doi.org/10.1017/S0954579415000267 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278 [article] Psychopathic personality development from ages 9 to 18: Genes and environment [Texte imprimé et/ou numérique] / Catherine TUVBLAD, Auteur ; Pan WANG, Auteur ; Serena BEZDJIAN, Auteur ; Adrian RAINE, Auteur ; Laura A. BAKER, Auteur . - p.27-44. Langues : Anglais (eng) in Development and Psychopathology > 28-1 (February 2016) . - p.27-44 Index. décimale : PER Périodiques Résumé : The genetic and environmental etiology of individual differences was examined in initial level and change in psychopathic personality from ages 9 to 18 years. A piecewise growth curve model, in which the first change score (G1) influenced all ages (9–10, 11–13, 14–15, and 16–18 years) and the second change score (G2) only influenced ages 14–15 and 16–18 years, fit the data better did than the standard single slope model, suggesting a turning point from childhood to adolescence. The results indicated that variations in levels and both change scores were mainly due to genetic (A) and nonshared environmental (E) influences (i.e., AE structure for G0, G1, and G2). No sex differences were found except on the mean values of level and change scores. Based on caregiver ratings, about 81% of variance in G0, 89% of variance in G1, and 94% of variance in G2 were explained by genetic factors, whereas for youth self-reports, these three proportions were 94%, 71%, and 66%, respectively. The larger contribution of genetic variance and covariance in caregiver ratings than in youth self-reports may suggest that caregivers considered the changes in their children to be more similar as compared to how the children viewed themselves. En ligne : http://dx.doi.org/10.1017/S0954579415000267 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=278

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