Sex differences in socioemotional functioning, attentional bias, and gray matter volume in maltreated children: A multilevel investigation / Philip A. KELLY in Development and Psychopathology, 27-4 (Part 2) (November 2015)  

Public ISBD [article]  inDevelopment and Psychopathology > 27-4 (Part 2) (November 2015) . - p.1591-1609 Titre : Sex differences in socioemotional functioning, attentional bias, and gray matter volume in maltreated children: A multilevel investigation Type de document : Texte imprimé et/ou numérique Auteurs : Philip A. KELLY, Auteur ; Essi VIDING, Auteur ; Vanessa B. PUETZ, Auteur ; Amy L. PALMER, Auteur ; Andrea MECHELLI, Auteur ; Jean-Baptiste PINGAULT, Auteur ; Sophie SAMUEL, Auteur ; Eamon J. MCCRORY, Auteur Article en page(s) : p.1591-1609 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : While maltreatment is known to impact social and emotional functioning, threat processing, and neural structure, the potentially dimorphic influence of sex on these outcomes remains relatively understudied. We investigated sex differences across these domains in a large community sample of children aged 10 to 14 years (n = 122) comprising 62 children with verified maltreatment experience and 60 well-matched nonmaltreated peers. The maltreated group relative to the nonmaltreated comparison group exhibited poorer social and emotional functioning (more peer problems and heightened emotional reactivity). Cognitively, they displayed a pattern of attentional avoidance of threat in a visual dot-probe task. Similar patterns were observed in males and females in these domains. Reduced gray matter volume was found to characterize the maltreated group in the medial orbitofrontal cortex, bilateral middle temporal lobes, and bilateral supramarginal gyrus; sex differences were observed only in the supramarginal gyrus. In addition, a disordinal interaction between maltreatment exposure and sex was found in the postcentral gyrus. Finally, attentional avoidance to threat mediated the relationship between maltreatment and emotional reactivity, and medial orbitofrontal cortex gray matter volume mediated the relationship between maltreatment and peer functioning. Similar mediation patterns were observed across sexes. This study highlights the utility of combining multiple levels of analysis when studying the “latent vulnerability” engendered by childhood maltreatment and yields tentative findings regarding a neural basis of sex differences in long-term outcomes for maltreated children. En ligne : http://dx.doi.org/10.1017/S0954579415000966 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273 [article] Sex differences in socioemotional functioning, attentional bias, and gray matter volume in maltreated children: A multilevel investigation [Texte imprimé et/ou numérique] / Philip A. KELLY, Auteur ; Essi VIDING, Auteur ; Vanessa B. PUETZ, Auteur ; Amy L. PALMER, Auteur ; Andrea MECHELLI, Auteur ; Jean-Baptiste PINGAULT, Auteur ; Sophie SAMUEL, Auteur ; Eamon J. MCCRORY, Auteur . - p.1591-1609. Langues : Anglais (eng) in Development and Psychopathology > 27-4 (Part 2) (November 2015) . - p.1591-1609 Index. décimale : PER Périodiques Résumé : While maltreatment is known to impact social and emotional functioning, threat processing, and neural structure, the potentially dimorphic influence of sex on these outcomes remains relatively understudied. We investigated sex differences across these domains in a large community sample of children aged 10 to 14 years (n = 122) comprising 62 children with verified maltreatment experience and 60 well-matched nonmaltreated peers. The maltreated group relative to the nonmaltreated comparison group exhibited poorer social and emotional functioning (more peer problems and heightened emotional reactivity). Cognitively, they displayed a pattern of attentional avoidance of threat in a visual dot-probe task. Similar patterns were observed in males and females in these domains. Reduced gray matter volume was found to characterize the maltreated group in the medial orbitofrontal cortex, bilateral middle temporal lobes, and bilateral supramarginal gyrus; sex differences were observed only in the supramarginal gyrus. In addition, a disordinal interaction between maltreatment exposure and sex was found in the postcentral gyrus. Finally, attentional avoidance to threat mediated the relationship between maltreatment and emotional reactivity, and medial orbitofrontal cortex gray matter volume mediated the relationship between maltreatment and peer functioning. Similar mediation patterns were observed across sexes. This study highlights the utility of combining multiple levels of analysis when studying the “latent vulnerability” engendered by childhood maltreatment and yields tentative findings regarding a neural basis of sex differences in long-term outcomes for maltreated children. En ligne : http://dx.doi.org/10.1017/S0954579415000966 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=273

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