Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder / Simon TRENT in Molecular Autism, (March 2014)  

Public ISBD [article]  inMolecular Autism > (March 2014) . - p.1-11 Titre : Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder Type de document : Texte imprimé et/ou numérique Auteurs : Simon TRENT, Auteur ; Jonathan P. FRY, Auteur ; Obah A. OJARIKRE, Auteur ; William DAVIES, Auteur Article en page(s) : p.1-11 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The 39,XY*O mouse, which lacks the orthologues of the ADHD and autism candidate genes STS (steroid sulphatase) and ASMT (acetylserotonin O-methyltransferase), exhibits behavioural phenotypes relevant to developmental disorders. The neurobiology underlying these phenotypes is unclear, although there is evidence for serotonergic abnormalities in the striatum and hippocampus. En ligne : http://dx.doi.org/10.1186/2040-2392-5-21 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276 [article] Altered brain gene expression but not steroid biochemistry in a genetic mouse model of neurodevelopmental disorder [Texte imprimé et/ou numérique] / Simon TRENT, Auteur ; Jonathan P. FRY, Auteur ; Obah A. OJARIKRE, Auteur ; William DAVIES, Auteur . - p.1-11. Langues : Anglais (eng) in Molecular Autism > (March 2014) . - p.1-11 Index. décimale : PER Périodiques Résumé : The 39,XY*O mouse, which lacks the orthologues of the ADHD and autism candidate genes STS (steroid sulphatase) and ASMT (acetylserotonin O-methyltransferase), exhibits behavioural phenotypes relevant to developmental disorders. The neurobiology underlying these phenotypes is unclear, although there is evidence for serotonergic abnormalities in the striatum and hippocampus. En ligne : http://dx.doi.org/10.1186/2040-2392-5-21 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=276

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