Correction to: Exploring Social Biomarkers in HighFunctioning Adults with Autism and Asperger's Versus Healthy Controls: A CrossSectional Analysis / Marta DEL VALLE RUBIDO in Journal of Autism and Developmental Disorders, 50-12 (December 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-12 (December 2020) . - p.4431-4432 Titre : Correction to: Exploring Social Biomarkers in HighFunctioning Adults with Autism and Asperger's Versus Healthy Controls: A CrossSectional Analysis Type de document : Texte imprimé et/ou numérique Auteurs : Marta DEL VALLE RUBIDO, Auteur ; Eric HOLLANDER, Auteur ; James T MCCRACKEN, Auteur ; Frederick SHIC, Auteur ; Jana NOELDEKE, Auteur ; Lauren BOAK, Auteur ; Omar KHWAJA, Auteur ; Shamil SADIKHOV, Auteur ; Paulo FONTOURA, Auteur ; Daniel UMBRICHT, Auteur Article en page(s) : p.4431-4432 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The original version of this article unfortunately contained a mistake in CI values in Table 2. En ligne : http://dx.doi.org/10.1007/s10803-020-04522-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 [article] Correction to: Exploring Social Biomarkers in HighFunctioning Adults with Autism and Asperger's Versus Healthy Controls: A CrossSectional Analysis [Texte imprimé et/ou numérique] / Marta DEL VALLE RUBIDO, Auteur ; Eric HOLLANDER, Auteur ; James T MCCRACKEN, Auteur ; Frederick SHIC, Auteur ; Jana NOELDEKE, Auteur ; Lauren BOAK, Auteur ; Omar KHWAJA, Auteur ; Shamil SADIKHOV, Auteur ; Paulo FONTOURA, Auteur ; Daniel UMBRICHT, Auteur . - p.4431-4432. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-12 (December 2020) . - p.4431-4432 Index. décimale : PER Périodiques Résumé : The original version of this article unfortunately contained a mistake in CI values in Table 2. En ligne : http://dx.doi.org/10.1007/s10803-020-04522-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434

Exploring Social Biomarkers in High-Functioning Adults with Autism and Asperger's Versus Healthy Controls: A Cross-Sectional Analysis / Marta DEL VALLE RUBIDO in Journal of Autism and Developmental Disorders, 50-12 (December 2020)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 50-12 (December 2020) . - p.4412-4430 Titre : Exploring Social Biomarkers in High-Functioning Adults with Autism and Asperger's Versus Healthy Controls: A Cross-Sectional Analysis Type de document : Texte imprimé et/ou numérique Auteurs : Marta DEL VALLE RUBIDO, Auteur ; Eric HOLLANDER, Auteur ; James T MCCRACKEN, Auteur ; Frederick SHIC, Auteur ; Jana NOELDEKE, Auteur ; Lauren BOAK, Auteur ; Omar KHWAJA, Auteur ; Shamil SADIKHOV, Auteur ; Paulo FONTOURA, Auteur ; Daniel UMBRICHT, Auteur Article en page(s) : p.4412-4430 Langues : Anglais (eng) Mots-clés : Biomarker  Eye movement  Olfactory  Social cognition  Curemark, Coronado Biosciences, Forest, Simons Foundation, Foundation for Prader  Willi Research, and the Orphan Products Division of the Food and Drug  Administration, and has intellectual property relating to oxytocin and autism. FS  has provided consultation to Roche and Janssen Pharmaceutical and has received  research grants from Roche, NIH, and the Simons Foundation. JTM has served as a  consultant for Roche and Dart Neuroscience, has received research grants from Roche,  and has received study drug from Shire and AstraZeneca. FS has received research  funding from Roche and Janssen Pharmaceuticals. MVR, DU, JN, LB, OK, SS and PF are  full-time employees of F. Hoffmann-La Roche. Index. décimale : PER Périodiques Résumé : Biomarkers for autism spectrum disorder (ASD) are lacking but would facilitate drug development for the core deficits of the disorder. We evaluated markers proposed for characterization of differences in social communication and interaction in adults with ASD versus healthy controls (HC) for utility as biomarkers. Data pooled from an observational study and baseline data from a placebo-controlled study were analyzed. Between-group differences were observed in eye-tracking tasks for activity monitoring, biomotion, human activity preference, composite score (p?=?0.0001-0.037) and pupillometry (various tasks, p?=?0.017-0.05). Impaired olfaction was more common in the ASD sample versus HC (p?=?0.018). Our preliminary results suggest the potential use for stratification and response sub-analyses outcome-prediction of specific eye-tracking tasks, pupillometry and olfaction tests in ASD trials. En ligne : http://dx.doi.org/10.1007/s10803-020-04493-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434 [article] Exploring Social Biomarkers in High-Functioning Adults with Autism and Asperger's Versus Healthy Controls: A Cross-Sectional Analysis [Texte imprimé et/ou numérique] / Marta DEL VALLE RUBIDO, Auteur ; Eric HOLLANDER, Auteur ; James T MCCRACKEN, Auteur ; Frederick SHIC, Auteur ; Jana NOELDEKE, Auteur ; Lauren BOAK, Auteur ; Omar KHWAJA, Auteur ; Shamil SADIKHOV, Auteur ; Paulo FONTOURA, Auteur ; Daniel UMBRICHT, Auteur . - p.4412-4430. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 50-12 (December 2020) . - p.4412-4430 Mots-clés : Biomarker  Eye movement  Olfactory  Social cognition  Curemark, Coronado Biosciences, Forest, Simons Foundation, Foundation for Prader  Willi Research, and the Orphan Products Division of the Food and Drug  Administration, and has intellectual property relating to oxytocin and autism. FS  has provided consultation to Roche and Janssen Pharmaceutical and has received  research grants from Roche, NIH, and the Simons Foundation. JTM has served as a  consultant for Roche and Dart Neuroscience, has received research grants from Roche,  and has received study drug from Shire and AstraZeneca. FS has received research  funding from Roche and Janssen Pharmaceuticals. MVR, DU, JN, LB, OK, SS and PF are  full-time employees of F. Hoffmann-La Roche. Index. décimale : PER Périodiques Résumé : Biomarkers for autism spectrum disorder (ASD) are lacking but would facilitate drug development for the core deficits of the disorder. We evaluated markers proposed for characterization of differences in social communication and interaction in adults with ASD versus healthy controls (HC) for utility as biomarkers. Data pooled from an observational study and baseline data from a placebo-controlled study were analyzed. Between-group differences were observed in eye-tracking tasks for activity monitoring, biomotion, human activity preference, composite score (p?=?0.0001-0.037) and pupillometry (various tasks, p?=?0.017-0.05). Impaired olfaction was more common in the ASD sample versus HC (p?=?0.018). Our preliminary results suggest the potential use for stratification and response sub-analyses outcome-prediction of specific eye-tracking tasks, pupillometry and olfaction tests in ASD trials. En ligne : http://dx.doi.org/10.1007/s10803-020-04493-5 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=434

Factor structure and psychometric properties of the revised Home Situations Questionnaire for autism spectrum disorder: The Home Situations Questionnaire-Autism Spectrum Disorder / Monali CHOWDHURY in Autism, 20-5 (July 2016)  

Public ISBD [article]  inAutism > 20-5 (July 2016) . - p.528-537 Titre : Factor structure and psychometric properties of the revised Home Situations Questionnaire for autism spectrum disorder: The Home Situations Questionnaire-Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Monali CHOWDHURY, Auteur ; Michael G. AMAN, Auteur ; Luc LECAVALIER, Auteur ; Tristram SMITH, Auteur ; Cynthia JOHNSON, Auteur ; Naomi SWIEZY, Auteur ; James T MCCRACKEN, Auteur ; Bryan KING, Auteur ; Christopher J MCDOUGLE, Auteur ; Karen E. BEARSS, Auteur ; Yanhong DENG, Auteur ; Lawrence SCAHILL, Auteur Article en page(s) : p.528-537 Langues : Anglais (eng) Mots-clés : non-compliance  psychometric properties Index. décimale : PER Périodiques Résumé : Previously, we adapted the Home Situations Questionnaire to measure behavioral non-compliance in everyday settings in children with pervasive developmental disorders. In this study, we further revised this instrument for use in autism spectrum disorder and examined its psychometric properties (referred to as the Home Situations Questionnaire-Autism Spectrum Disorder). To cover a broader range of situations and improve reliability, we prepared seven new items describing situations in which children with autism spectrum disorder might display non-compliance. Parents completed ratings of 242 children with autism spectrum disorder with accompanying disruptive behaviors (ages 4–14?years) participating in one of two randomized clinical trials. Results from an exploratory factor analysis indicated that the Home Situations Questionnaire-Autism Spectrum Disorder consists of two 12-item factors: Socially Inflexible (??=?0.84) and Demand Specific (??=?0.89). One-to-two-week test–retest reliability was statistically significant for all scored items and also for subscale totals. The pattern of correspondence between the Home Situations Questionnaire-Autism Spectrum Disorder and parent-rated problem behavior, clinician-rated repetitive behavior, adaptive behavior, and IQ provided evidence for concurrent and divergent validity of the Home Situations Questionnaire-Autism Spectrum Disorder. Overall, the results suggest that the Home Situations Questionnaire-Autism Spectrum Disorder is an adequate measure for assessing non-compliance in a variety of situations in this population, and use of its two subscales will likely provide a more refined interpretation of ratings. En ligne : http://dx.doi.org/10.1177/1362361315593941 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290 [article] Factor structure and psychometric properties of the revised Home Situations Questionnaire for autism spectrum disorder: The Home Situations Questionnaire-Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Monali CHOWDHURY, Auteur ; Michael G. AMAN, Auteur ; Luc LECAVALIER, Auteur ; Tristram SMITH, Auteur ; Cynthia JOHNSON, Auteur ; Naomi SWIEZY, Auteur ; James T MCCRACKEN, Auteur ; Bryan KING, Auteur ; Christopher J MCDOUGLE, Auteur ; Karen E. BEARSS, Auteur ; Yanhong DENG, Auteur ; Lawrence SCAHILL, Auteur . - p.528-537. Langues : Anglais (eng) in Autism > 20-5 (July 2016) . - p.528-537 Mots-clés : non-compliance  psychometric properties Index. décimale : PER Périodiques Résumé : Previously, we adapted the Home Situations Questionnaire to measure behavioral non-compliance in everyday settings in children with pervasive developmental disorders. In this study, we further revised this instrument for use in autism spectrum disorder and examined its psychometric properties (referred to as the Home Situations Questionnaire-Autism Spectrum Disorder). To cover a broader range of situations and improve reliability, we prepared seven new items describing situations in which children with autism spectrum disorder might display non-compliance. Parents completed ratings of 242 children with autism spectrum disorder with accompanying disruptive behaviors (ages 4–14?years) participating in one of two randomized clinical trials. Results from an exploratory factor analysis indicated that the Home Situations Questionnaire-Autism Spectrum Disorder consists of two 12-item factors: Socially Inflexible (??=?0.84) and Demand Specific (??=?0.89). One-to-two-week test–retest reliability was statistically significant for all scored items and also for subscale totals. The pattern of correspondence between the Home Situations Questionnaire-Autism Spectrum Disorder and parent-rated problem behavior, clinician-rated repetitive behavior, adaptive behavior, and IQ provided evidence for concurrent and divergent validity of the Home Situations Questionnaire-Autism Spectrum Disorder. Overall, the results suggest that the Home Situations Questionnaire-Autism Spectrum Disorder is an adequate measure for assessing non-compliance in a variety of situations in this population, and use of its two subscales will likely provide a more refined interpretation of ratings. En ligne : http://dx.doi.org/10.1177/1362361315593941 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=290

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