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Sensitivity and Specificity of the ADOS-2 Algorithm in a Large German Sample / Juliane E. MEDDA in Journal of Autism and Developmental Disorders, 49-2 (February 2019)

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inJournal of Autism and Developmental Disorders > 49-2 (February 2019) . - p.750-761

Titre :

Sensitivity and Specificity of the ADOS-2 Algorithm in a Large German Sample

Type de document :

texte imprimé

Auteurs :

Juliane E. MEDDA, Auteur ; Hannah CHOLEMKERY, Auteur ; Christine M. FREITAG, Auteur

Article en page(s) :

p.750-761

Langues :

Anglais (eng)

Mots-clés :

Autism spectrum disorder Child psychiatric disorder Diagnostic validity Psychometric assessment

Index. décimale :

PER Périodiques

Résumé :

The aim of the present study was to establish diagnostic validity of the new algorithm of the Autism Diagnostic Observation Scale, the ADOS-2, to differentiate between ASD and other clinically relevant psychiatric and developmental disorders in a large German sample. Validity of ADOS and ADOS-2 diagnostic algorithms was established in 826 individuals (n = 455 autism, n = 216 autism spectrum, n = 155 non-ASD patients) by receiver operating curves. Confidence intervals overlapped largely for ADOS and ADOS-2 algorithms, confirming diagnostic validity of both algorithms. Adding information of the Social Communication Questionnaire and the Social Responsiveness Scale resulted in slightly improved classification rates for autism in Module 4. We thus replicated previous findings of the diagnostic validity of the ADOS-2 algorithms.

En ligne :

http://dx.doi.org/10.1007/s10803-018-3750-3

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