The neurobiology of self-processing in abused depressed adolescents / Karina QUEVEDO in Development and Psychopathology, 29-3 (August 2017)  

Public ISBD [article]  inDevelopment and Psychopathology > 29-3 (August 2017) . - p.1057-1073 Titre : The neurobiology of self-processing in abused depressed adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Karina QUEVEDO, Auteur ; Rowena NG, Auteur ; Hannah SCOTT, Auteur ; Garry SMYDA, Auteur ; Jennifer H. PFEIFER, Auteur ; Sandra MALONE, Auteur Article en page(s) : p.1057-1073 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Abstract Maltreatment is associated with chronic depression, high negative self-attributions, and lifetime psychopathology. Adolescence is a sensitive period for the formation of self-concept. Identifying neurobiomarkers of self-processing in depressed adolescents with and without maltreatment may parse the effects of trauma and depression on self-development and chronic psychopathology. Depressed adolescents (n = 86) maltreated due to omission (DO, n = 13) or commission (DCM, n = 28) or without maltreatment (DC, n = 45), and HCs (HC, n = 37) appraised positive and negative self-descriptors in the scanner. DCM and DO showed hypoactivity in the dorsal anterior cingulate cortex (dACC) while processing positive versus negative self-descriptors compared to DC youth, who in turn showed reduced dACC recruitment versus HC. HC youth showed the highest activation in the dACC and striatum during positive self-descriptors; these regions showed a linear decline in activity across DC, DO, and DCM. Low dACC activity to positive versus negative self-descriptors was linked to inadequate coregulation of children's emotions by parents. Negative self-cognitions prevalent in DCM and DO adolescents may be perpetuated by activity in the dACC and striatum. Reduced activation of the dACC and striatum for positive self-descriptors, coupled with enhanced activity for negative self-descriptors, may heighten the risk for persistent depression. En ligne : http://dx.doi.org/10.1017/s0954579416001024 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312 [article] The neurobiology of self-processing in abused depressed adolescents [Texte imprimé et/ou numérique] / Karina QUEVEDO, Auteur ; Rowena NG, Auteur ; Hannah SCOTT, Auteur ; Garry SMYDA, Auteur ; Jennifer H. PFEIFER, Auteur ; Sandra MALONE, Auteur . - p.1057-1073. Langues : Anglais (eng) in Development and Psychopathology > 29-3 (August 2017) . - p.1057-1073 Index. décimale : PER Périodiques Résumé : Abstract Maltreatment is associated with chronic depression, high negative self-attributions, and lifetime psychopathology. Adolescence is a sensitive period for the formation of self-concept. Identifying neurobiomarkers of self-processing in depressed adolescents with and without maltreatment may parse the effects of trauma and depression on self-development and chronic psychopathology. Depressed adolescents (n = 86) maltreated due to omission (DO, n = 13) or commission (DCM, n = 28) or without maltreatment (DC, n = 45), and HCs (HC, n = 37) appraised positive and negative self-descriptors in the scanner. DCM and DO showed hypoactivity in the dorsal anterior cingulate cortex (dACC) while processing positive versus negative self-descriptors compared to DC youth, who in turn showed reduced dACC recruitment versus HC. HC youth showed the highest activation in the dACC and striatum during positive self-descriptors; these regions showed a linear decline in activity across DC, DO, and DCM. Low dACC activity to positive versus negative self-descriptors was linked to inadequate coregulation of children's emotions by parents. Negative self-cognitions prevalent in DCM and DO adolescents may be perpetuated by activity in the dACC and striatum. Reduced activation of the dACC and striatum for positive self-descriptors, coupled with enhanced activity for negative self-descriptors, may heighten the risk for persistent depression. En ligne : http://dx.doi.org/10.1017/s0954579416001024 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=312

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