[article]
| Titre : |
Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Pablo Jose GONZALEZ-DOMENECH, Auteur ; Francisco DIAZ ATIENZA, Auteur ; Carlos GARCIA PABLOS, Auteur ; Maria Luisa FERNANDEZ SOTO, Auteur ; Jose Maria MARTINEZ-ORTEGA, Auteur ; Luis GUTIERREZ-ROJAS, Auteur |
| Article en page(s) : |
p.935-948 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Autism spectrum disorder Beta-casomorphin Casein Diet Gluten |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The use of alternative interventions, such as gluten-free and casein-free (GFCF) diets, is frequent due to limited therapies for Autism Spectrum Disorder (ASD). Our aims were to determine the influence of a GFCF diet on behavior disorders in children and adolescents diagnosed with ASD and the potential association with urinary beta-casomorphin concentrations. Thirty-seven patients were recruited for this crossover trial. Each patient consumed a normal diet (including gluten and casein) for 6 months and a GFCF diet for another 6 months. The order of the intervention (beginning with normal diet or with GFCF diet) was assigned randomly. Patients were evaluated at three time-points (at the beginning of the study, after normal diet and after GFCF diet). Questionnaires regarding behavior and autism and dietary adherence were completed and urinary beta-casomorphin concentrations were determined at each time-point. No significant behavioral changes and no association with urinary beta-casomorphin concentrations were found after GFCF diet. A 6-month GFCF diet do not induce significant changes in behavioral symptoms of autism and urinary beta-casomorphin concentrations. Further studies with a long follow-up period similar to ours and including placebo and blinding elements are needed to identify better those respondents to GFCF diets. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-019-04333-1 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=419 |
in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.935-948
[article] Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial [Texte imprimé et/ou numérique] / Pablo Jose GONZALEZ-DOMENECH, Auteur ; Francisco DIAZ ATIENZA, Auteur ; Carlos GARCIA PABLOS, Auteur ; Maria Luisa FERNANDEZ SOTO, Auteur ; Jose Maria MARTINEZ-ORTEGA, Auteur ; Luis GUTIERREZ-ROJAS, Auteur . - p.935-948. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 50-3 (March 2020) . - p.935-948
| Mots-clés : |
Autism spectrum disorder Beta-casomorphin Casein Diet Gluten |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The use of alternative interventions, such as gluten-free and casein-free (GFCF) diets, is frequent due to limited therapies for Autism Spectrum Disorder (ASD). Our aims were to determine the influence of a GFCF diet on behavior disorders in children and adolescents diagnosed with ASD and the potential association with urinary beta-casomorphin concentrations. Thirty-seven patients were recruited for this crossover trial. Each patient consumed a normal diet (including gluten and casein) for 6 months and a GFCF diet for another 6 months. The order of the intervention (beginning with normal diet or with GFCF diet) was assigned randomly. Patients were evaluated at three time-points (at the beginning of the study, after normal diet and after GFCF diet). Questionnaires regarding behavior and autism and dietary adherence were completed and urinary beta-casomorphin concentrations were determined at each time-point. No significant behavioral changes and no association with urinary beta-casomorphin concentrations were found after GFCF diet. A 6-month GFCF diet do not induce significant changes in behavioral symptoms of autism and urinary beta-casomorphin concentrations. Further studies with a long follow-up period similar to ours and including placebo and blinding elements are needed to identify better those respondents to GFCF diets. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-019-04333-1 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=419 |
|
Influence of a Combined Gluten-Free and Casein-Free Diet on Behavior Disorders in Children and Adolescents Diagnosed with Autism Spectrum Disorder: A 12-Month Follow-Up Clinical Trial in Journal of Autism and Developmental Disorders, 50-3 (March 2020)
