Brief Report: Abnormal Association Between the Thalamus and Brain Size in Asperger’s Disorder / Antonio Y. HARDAN in Journal of Autism and Developmental Disorders, 38-2 (February 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-2 (February 2008) . - p.390-394 Titre : Brief Report: Abnormal Association Between the Thalamus and Brain Size in Asperger’s Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Antonio Y. HARDAN, Auteur ; Nadine M. MELHEM, Auteur ; Nancy J. MINSHEW, Auteur ; Ragy R. GIRGIS, Auteur ; Jason ADAMS, Auteur ; Andrew R. GILBERT, Auteur ; Matcheri S. KESHAVAN, Auteur Année de publication : 2008 Article en page(s) : p.390-394 Langues : Anglais (eng) Mots-clés : Asperger’s-disorder Thalamus MRI Brain-size Autism Volume Index. décimale : PER Périodiques Résumé : The objective of this study was to examine the relationship between thalamic volume and brain size in individuals with Asperger’s disorder (ASP). Volumetric measurements of the thalamus were performed on MRI scans obtained from 12 individuals with ASP (age range: 10–35 years) and 12 healthy controls (age range: 9–33 years). A positive correlation was found between total brain volume and thalamic size in controls, but not in ASP subjects. This occurred in the absence of differences in mean thalamic volumes between the study groups. Findings from this investigation point to an abnormal relationship between the thalamus and its projection areas in ASP and are consistent with similar studies in autism, supporting that these disorders are qualitatively similar and possibly quantitatively different. En ligne : http://dx.doi.org/10.1007/s10803-007-0385-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=319 [article] Brief Report: Abnormal Association Between the Thalamus and Brain Size in Asperger’s Disorder [Texte imprimé et/ou numérique] / Antonio Y. HARDAN, Auteur ; Nadine M. MELHEM, Auteur ; Nancy J. MINSHEW, Auteur ; Ragy R. GIRGIS, Auteur ; Jason ADAMS, Auteur ; Andrew R. GILBERT, Auteur ; Matcheri S. KESHAVAN, Auteur . - 2008 . - p.390-394. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-2 (February 2008) . - p.390-394 Mots-clés : Asperger’s-disorder Thalamus MRI Brain-size Autism Volume Index. décimale : PER Périodiques Résumé : The objective of this study was to examine the relationship between thalamic volume and brain size in individuals with Asperger’s disorder (ASP). Volumetric measurements of the thalamus were performed on MRI scans obtained from 12 individuals with ASP (age range: 10–35 years) and 12 healthy controls (age range: 9–33 years). A positive correlation was found between total brain volume and thalamic size in controls, but not in ASP subjects. This occurred in the absence of differences in mean thalamic volumes between the study groups. Findings from this investigation point to an abnormal relationship between the thalamus and its projection areas in ASP and are consistent with similar studies in autism, supporting that these disorders are qualitatively similar and possibly quantitatively different. En ligne : http://dx.doi.org/10.1007/s10803-007-0385-1 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=319

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