[article] 
inJournal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2784-2793

Titre :	Melatonin Treatment and Adequate Sleep Hygiene Interventions in Children with Autism Spectrum Disorder: A Randomized Controlled Trial
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Masaharu HAYASHI, Auteur ; Kazuo MISHIMA, Auteur ; Michio FUKUMIZU, Auteur ; Hiroyuki TAKAHASHI, Auteur ; Yuko ISHIKAWA, Auteur ; Izumi HAMADA, Auteur ; Hideyuki SUGIOKA, Auteur ; Osamu YOTSUYA, Auteur ; Yushiro YAMASHITA, Auteur
Article en page(s) :	p.2784-2793
Langues :	Anglais (eng)
Mots-clés :	Autism spectrum disorder  Melatonin  Randomized controlled trial  Sleep hygiene interventions  Sleep problems
Index. décimale :	PER Périodiques
Résumé :	Robust clinical evidence has not been available for melatonin, a drug commonly administered for treating sleep problems of children with autism spectrum disorder (ASD). In a phase 3 randomized, placebo-controlled clinical trial, we administered 1-mg melatonin (n=65), 4-mg melatonin (n=65), or placebo (n=66) to196 children with ASD once daily before bedtime under adequate sleep hygiene interventions. The primary outcome was sleep onset latency (SOL) assessed with the electronic sleep diary. SOL shortened significantly in the 1- and 4-mg melatonin groups compared to the placebo group (- 22.0, - 28.0, and - 5.0 min, respectively; p?
En ligne :	http://dx.doi.org/10.1007/s10803-021-05139-w
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

[article] Melatonin Treatment and Adequate Sleep Hygiene Interventions in Children with Autism Spectrum Disorder: A Randomized Controlled Trial [Texte imprimé et/ou numérique] / Masaharu HAYASHI, Auteur ; Kazuo MISHIMA, Auteur ; Michio FUKUMIZU, Auteur ; Hiroyuki TAKAHASHI, Auteur ; Yuko ISHIKAWA, Auteur ; Izumi HAMADA, Auteur ; Hideyuki SUGIOKA, Auteur ; Osamu YOTSUYA, Auteur ; Yushiro YAMASHITA, Auteur . - p.2784-2793.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2784-2793

Mots-clés :	Autism spectrum disorder  Melatonin  Randomized controlled trial  Sleep hygiene interventions  Sleep problems
Index. décimale :	PER Périodiques
Résumé :	Robust clinical evidence has not been available for melatonin, a drug commonly administered for treating sleep problems of children with autism spectrum disorder (ASD). In a phase 3 randomized, placebo-controlled clinical trial, we administered 1-mg melatonin (n=65), 4-mg melatonin (n=65), or placebo (n=66) to196 children with ASD once daily before bedtime under adequate sleep hygiene interventions. The primary outcome was sleep onset latency (SOL) assessed with the electronic sleep diary. SOL shortened significantly in the 1- and 4-mg melatonin groups compared to the placebo group (- 22.0, - 28.0, and - 5.0 min, respectively; p?
En ligne :	http://dx.doi.org/10.1007/s10803-021-05139-w
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474