Psychotic experiences are associated with health anxiety and functional somatic symptoms in preadolescence / M. K. RIMVALL in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.524-532 Titre : Psychotic experiences are associated with health anxiety and functional somatic symptoms in preadolescence Type de document : Texte imprimé et/ou numérique Auteurs : M. K. RIMVALL, Auteur ; C. P. JESPERSEN, Auteur ; L. CLEMMENSEN, Auteur ; A. MUNKHOLM, Auteur ; A. M. SKOVGAARD, Auteur ; F. VERHULST, Auteur ; J. VAN OS, Auteur ; C. U. RASK, Auteur ; P. JEPPESEN, Auteur Article en page(s) : p.524-532 Langues : Anglais (eng) Mots-clés : Psychosis  anxiety  epidemiology  somatization Index. décimale : PER Périodiques Résumé : BACKGROUND: Health anxiety (HA) is an increasing public health problem related to increased health service costs, and associated with functional somatic symptoms (FSS) and considerable personal suffering. Abnormal bodily experiences which may resemble HA and FSS are common in psychotic disorders, but a potential link between HA and psychosis vulnerability in childhood is largely unexplored. The current study estimates the association between subclinical psychotic experiences (PE) and HA and FSS in a general population cohort of preadolescents. METHODS: The study population consisted of 1,572 11-12-year-old children from the Copenhagen Child Cohort 2000. PE were comprehensibly assessed as either present or not present using the Kiddie Schedule of Affective Disorders and Schizophrenia psychosis section. HA and FSS were assessed by self-report on validated questionnaires. Additional variables on general psychopathology, puberty, and chronic somatic illness were also obtained. RESULTS: Psychotic experiences were associated with the top 10% high scores of HA (Odds Ratio (OR) 3.2; 95% CI: 2.1-4.8) and FSS (OR 4.6; 95% CI: 3.1-6.9) in univariate analyses. After mutual adjustment, the association was reduced to (HA: OR 2.3; 95% CI: 1.5-3.5; FSS: OR 3.7; 95% CI: 2.4-4.7), suggesting interdependence. Further adjustment for potential confounders and general psychopathology only reduced the associations slightly: HA OR 2.2 (95% CI: 1.4-3.4); FSS OR 3.3 (95% CI: 2.1-5.2). Secondary analyses of subdimensions of HA showed that PE were associated with fears (OR 3.0; 95% CI: 2.0-4.6) and daily impact of HA symptoms (OR 5.0; 95% CI: 3.4-7.5), but not help seeking (OR 1.2; 95% CI: 0.7-2.1). CONCLUSIONS: This is the first study to investigate the associations between PE and HA and FSS, respectively. PE were significantly associated with HA and FSS over and above general psychopathology in preadolescence. Individuals with PE expressed high levels of health-related fears and daily impact, but no corresponding help-seeking behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12986 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 [article] Psychotic experiences are associated with health anxiety and functional somatic symptoms in preadolescence [Texte imprimé et/ou numérique] / M. K. RIMVALL, Auteur ; C. P. JESPERSEN, Auteur ; L. CLEMMENSEN, Auteur ; A. MUNKHOLM, Auteur ; A. M. SKOVGAARD, Auteur ; F. VERHULST, Auteur ; J. VAN OS, Auteur ; C. U. RASK, Auteur ; P. JEPPESEN, Auteur . - p.524-532. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.524-532 Mots-clés : Psychosis  anxiety  epidemiology  somatization Index. décimale : PER Périodiques Résumé : BACKGROUND: Health anxiety (HA) is an increasing public health problem related to increased health service costs, and associated with functional somatic symptoms (FSS) and considerable personal suffering. Abnormal bodily experiences which may resemble HA and FSS are common in psychotic disorders, but a potential link between HA and psychosis vulnerability in childhood is largely unexplored. The current study estimates the association between subclinical psychotic experiences (PE) and HA and FSS in a general population cohort of preadolescents. METHODS: The study population consisted of 1,572 11-12-year-old children from the Copenhagen Child Cohort 2000. PE were comprehensibly assessed as either present or not present using the Kiddie Schedule of Affective Disorders and Schizophrenia psychosis section. HA and FSS were assessed by self-report on validated questionnaires. Additional variables on general psychopathology, puberty, and chronic somatic illness were also obtained. RESULTS: Psychotic experiences were associated with the top 10% high scores of HA (Odds Ratio (OR) 3.2; 95% CI: 2.1-4.8) and FSS (OR 4.6; 95% CI: 3.1-6.9) in univariate analyses. After mutual adjustment, the association was reduced to (HA: OR 2.3; 95% CI: 1.5-3.5; FSS: OR 3.7; 95% CI: 2.4-4.7), suggesting interdependence. Further adjustment for potential confounders and general psychopathology only reduced the associations slightly: HA OR 2.2 (95% CI: 1.4-3.4); FSS OR 3.3 (95% CI: 2.1-5.2). Secondary analyses of subdimensions of HA showed that PE were associated with fears (OR 3.0; 95% CI: 2.0-4.6) and daily impact of HA symptoms (OR 5.0; 95% CI: 3.4-7.5), but not help seeking (OR 1.2; 95% CI: 0.7-2.1). CONCLUSIONS: This is the first study to investigate the associations between PE and HA and FSS, respectively. PE were significantly associated with HA and FSS over and above general psychopathology in preadolescence. Individuals with PE expressed high levels of health-related fears and daily impact, but no corresponding help-seeking behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12986 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392

The bidirectional association between sleep problems and autism spectrum disorder: a population-based cohort study / M. E. VERHOEFF in Molecular Autism, 9 (2018)  

Public ISBD [article]  inMolecular Autism > 9 (2018) . - 8p. Titre : The bidirectional association between sleep problems and autism spectrum disorder: a population-based cohort study Type de document : Texte imprimé et/ou numérique Auteurs : M. E. VERHOEFF, Auteur ; Laura M. E. BLANKEN, Auteur ; D. KOCEVSKA, Auteur ; V. R. MILEVA-SEITZ, Auteur ; Vincent W.V. JADDOE, Auteur ; T. WHITE, Auteur ; F. VERHULST, Auteur ; Mpcm LUIJK, Auteur ; H. TIEMEIER, Auteur Article en page(s) : 8p. Langues : Anglais (eng) Mots-clés : Autism  Bidirectional  Birth cohort  General population  Sleep problems Index. décimale : PER Périodiques Résumé : Background: Sleep difficulties are prevalent in children with autism spectrum disorder (ASD). The temporal nature of the association between sleep problems and ASD is unclear because longitudinal studies are lacking. Our aim is to clarify whether sleep problems precede and worsen autistic traits and ASD or occur as a consequence of the disorder. Methods: Repeated sleep measures were available at 1.5, 3, 6, and 9 years of age in 5151 children participating in the Generation R Study, a large prospective birth cohort in the Netherlands. Autistic traits were determined with the Pervasive Developmental Problems score (PDP) of the Child Behavior Checklist (CBCL) at 1.5 and 3 years and the Social Responsiveness Scale (SRS) at 6 years. This cohort included 81 children diagnosed with ASD. Results: Sleep problems in early childhood were prospectively associated with a higher SRS score, but not when correcting for baseline PDP score. By contrast, a higher SRS score and an ASD diagnosis were associated with more sleep problems at later ages, even when adjusting for baseline sleep problems. Likewise, a trajectory of increasing sleep problems was associated with ASD. Conclusions: Sleep problems and ASD are not bidirectionally associated. Sleep problems do not precede and worsen autistic behavior but rather co-occur with autistic traits in early childhood. Over time, children with ASD have an increase in sleep problems, whereas typically developing children have a decrease in sleep problems. Our findings suggest that sleep problems are part of the construct ASD. En ligne : http://dx.doi.org/10.1186/s13229-018-0194-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354 [article] The bidirectional association between sleep problems and autism spectrum disorder: a population-based cohort study [Texte imprimé et/ou numérique] / M. E. VERHOEFF, Auteur ; Laura M. E. BLANKEN, Auteur ; D. KOCEVSKA, Auteur ; V. R. MILEVA-SEITZ, Auteur ; Vincent W.V. JADDOE, Auteur ; T. WHITE, Auteur ; F. VERHULST, Auteur ; Mpcm LUIJK, Auteur ; H. TIEMEIER, Auteur . - 8p. Langues : Anglais (eng) in Molecular Autism > 9 (2018) . - 8p. Mots-clés : Autism  Bidirectional  Birth cohort  General population  Sleep problems Index. décimale : PER Périodiques Résumé : Background: Sleep difficulties are prevalent in children with autism spectrum disorder (ASD). The temporal nature of the association between sleep problems and ASD is unclear because longitudinal studies are lacking. Our aim is to clarify whether sleep problems precede and worsen autistic traits and ASD or occur as a consequence of the disorder. Methods: Repeated sleep measures were available at 1.5, 3, 6, and 9 years of age in 5151 children participating in the Generation R Study, a large prospective birth cohort in the Netherlands. Autistic traits were determined with the Pervasive Developmental Problems score (PDP) of the Child Behavior Checklist (CBCL) at 1.5 and 3 years and the Social Responsiveness Scale (SRS) at 6 years. This cohort included 81 children diagnosed with ASD. Results: Sleep problems in early childhood were prospectively associated with a higher SRS score, but not when correcting for baseline PDP score. By contrast, a higher SRS score and an ASD diagnosis were associated with more sleep problems at later ages, even when adjusting for baseline sleep problems. Likewise, a trajectory of increasing sleep problems was associated with ASD. Conclusions: Sleep problems and ASD are not bidirectionally associated. Sleep problems do not precede and worsen autistic behavior but rather co-occur with autistic traits in early childhood. Over time, children with ASD have an increase in sleep problems, whereas typically developing children have a decrease in sleep problems. Our findings suggest that sleep problems are part of the construct ASD. En ligne : http://dx.doi.org/10.1186/s13229-018-0194-8 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=354

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