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Mention de date : May 2019
Paru le : 01/05/2019 |
[n° ou bulletin]
[n° ou bulletin]
60-5 - May 2019 [Texte imprimé et/ou numérique] . - 2019. Langues : Anglais (eng)
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Exemplaires (1)
Code-barres | Cote | Support | Localisation | Section | Disponibilité |
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PER0001726 | PER JCP | Périodique | Centre d'Information et de Documentation du CRA Rhône-Alpes | PER - Périodiques | Exclu du prêt |
Dépouillements


Editorial: The psychopathology p factor: will it revolutionise the science and practice of child and adolescent psychiatry? / A. RONALD in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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Titre : Editorial: The psychopathology p factor: will it revolutionise the science and practice of child and adolescent psychiatry? Type de document : Texte imprimé et/ou numérique Auteurs : A. RONALD, Auteur Article en page(s) : p.497-499 Langues : Anglais (eng) Mots-clés : Psychopathology autism child and adolescent psychiatry genetics neurodevelopment p factor Index. décimale : PER Périodiques Résumé : The psychopathology p factor has emerged from a series of strong empirical studies, largely in the adult psychiatry literature. Here, some of the recent findings relating to the p factor in children and adolescents are considered and the implications for child and adolescent psychiatry are discussed. Is it essential to covary for 'p' when we study specific domains of psychopathology? Do neurodevelopmental conditions make up part of the psychopathology p factor? How do we treat the 'p factor' in clinics? This editorial considers some of the contributions from this issue of Journal of Child Psychology and Psychiatry together with the wider literature that speak to these issues. En ligne : http://dx.doi.org/10.1111/jcpp.13063 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.497-499[article] Editorial: The psychopathology p factor: will it revolutionise the science and practice of child and adolescent psychiatry? [Texte imprimé et/ou numérique] / A. RONALD, Auteur . - p.497-499.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.497-499
Mots-clés : Psychopathology autism child and adolescent psychiatry genetics neurodevelopment p factor Index. décimale : PER Périodiques Résumé : The psychopathology p factor has emerged from a series of strong empirical studies, largely in the adult psychiatry literature. Here, some of the recent findings relating to the p factor in children and adolescents are considered and the implications for child and adolescent psychiatry are discussed. Is it essential to covary for 'p' when we study specific domains of psychopathology? Do neurodevelopmental conditions make up part of the psychopathology p factor? How do we treat the 'p factor' in clinics? This editorial considers some of the contributions from this issue of Journal of Child Psychology and Psychiatry together with the wider literature that speak to these issues. En ligne : http://dx.doi.org/10.1111/jcpp.13063 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 Practitioner Review: Posttraumatic stress disorder and its treatment in children and adolescents / P. SMITH in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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Titre : Practitioner Review: Posttraumatic stress disorder and its treatment in children and adolescents Type de document : Texte imprimé et/ou numérique Auteurs : P. SMITH, Auteur ; Tim DALGLEISH, Auteur ; R. MEISER-STEDMAN, Auteur Article en page(s) : p.500-515 Langues : Anglais (eng) Mots-clés : Cognitive therapy diagnosis posttraumatic stress disorder trauma treatment trials Index. décimale : PER Périodiques Résumé : Important advances in understanding traumatic stress reactions in children and young people have been made in recent years. The aim of this review was to synthesise selected recent research findings, with a focus on their relevance to clinical practice. We therefore address: findings on the epidemiology of trauma exposure and Posttraumatic Stress Disorder (PTSD); recent changes to diagnostic classification; implications for screening and assessment of traumatic stress reactions; and treatment outcome studies including interventions for acute and chronic PTSD, dissemination of effective treatments into community settings, and early interventions. We conclude with recommendations for clinical practice and suggestions for future areas of research. En ligne : http://dx.doi.org/10.1111/jcpp.12983 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.500-515[article] Practitioner Review: Posttraumatic stress disorder and its treatment in children and adolescents [Texte imprimé et/ou numérique] / P. SMITH, Auteur ; Tim DALGLEISH, Auteur ; R. MEISER-STEDMAN, Auteur . - p.500-515.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.500-515
Mots-clés : Cognitive therapy diagnosis posttraumatic stress disorder trauma treatment trials Index. décimale : PER Périodiques Résumé : Important advances in understanding traumatic stress reactions in children and young people have been made in recent years. The aim of this review was to synthesise selected recent research findings, with a focus on their relevance to clinical practice. We therefore address: findings on the epidemiology of trauma exposure and Posttraumatic Stress Disorder (PTSD); recent changes to diagnostic classification; implications for screening and assessment of traumatic stress reactions; and treatment outcome studies including interventions for acute and chronic PTSD, dissemination of effective treatments into community settings, and early interventions. We conclude with recommendations for clinical practice and suggestions for future areas of research. En ligne : http://dx.doi.org/10.1111/jcpp.12983 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 The dysregulation profile in preschoolers with and without a family history of autism spectrum disorder / M. MILLER in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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Titre : The dysregulation profile in preschoolers with and without a family history of autism spectrum disorder Type de document : Texte imprimé et/ou numérique Auteurs : M. MILLER, Auteur ; A. M. IOSIF, Auteur ; Gregory S. YOUNG, Auteur ; L. J. BELL, Auteur ; A. J. SCHWICHTENBERG, Auteur ; T. HUTMAN, Auteur ; S. OZONOFF, Auteur Article en page(s) : p.516-523 Langues : Anglais (eng) Mots-clés : Dysregulation autism spectrum disorder high risk preschool siblings Index. décimale : PER Périodiques Résumé : BACKGROUND: The 'dysregulation profile' (DP) is a measure of emotional and behavioral dysregulation that may cut across diagnostic boundaries. Siblings of children with autism spectrum disorder (ASD) who do not develop ASD themselves are at risk for atypical outcomes including behavioral challenges and therefore may be a useful population in which to investigate the structure of the DP in preschoolers. METHODS: We sought to examine the factor structure and predictors of the DP in a sample enriched for a wide range of phenotypic variation-36-month-olds with and without family histories of ASD-and to determine whether children with genetic liability for ASD are at risk for a phenotype characterized by elevated dysregulation. Data were collected from 415 children with (n = 253) and without (n = 162) an older sibling with ASD, all without ASD themselves, at 18, 24, and 36 months of age. RESULTS: Our findings replicate prior reports, conducted in predominantly clinically referred and older samples, supporting the superiority of a bifactor model of the DP in the preschool period compared to the second-order and one-factor models. Examiner ratings were longitudinally and concurrently associated with the DP at 36 months of age. Family history of ASD was associated with higher dysregulation in the Anxious/Depressed dimension. CONCLUSIONS: These findings support the relevance of examining the structure of psychopathology in preschoolers and suggest that examiner observations as early as 18 months of age, particularly of overactivity, may help identify risk for later DP-related concerns. Non-ASD preschoolers with family histories of ASD may be at risk for a phenotype characterized by elevated dysregulation particularly in the Anxious/Depressed dimension by age 3. En ligne : http://dx.doi.org/10.1111/jcpp.13003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.516-523[article] The dysregulation profile in preschoolers with and without a family history of autism spectrum disorder [Texte imprimé et/ou numérique] / M. MILLER, Auteur ; A. M. IOSIF, Auteur ; Gregory S. YOUNG, Auteur ; L. J. BELL, Auteur ; A. J. SCHWICHTENBERG, Auteur ; T. HUTMAN, Auteur ; S. OZONOFF, Auteur . - p.516-523.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.516-523
Mots-clés : Dysregulation autism spectrum disorder high risk preschool siblings Index. décimale : PER Périodiques Résumé : BACKGROUND: The 'dysregulation profile' (DP) is a measure of emotional and behavioral dysregulation that may cut across diagnostic boundaries. Siblings of children with autism spectrum disorder (ASD) who do not develop ASD themselves are at risk for atypical outcomes including behavioral challenges and therefore may be a useful population in which to investigate the structure of the DP in preschoolers. METHODS: We sought to examine the factor structure and predictors of the DP in a sample enriched for a wide range of phenotypic variation-36-month-olds with and without family histories of ASD-and to determine whether children with genetic liability for ASD are at risk for a phenotype characterized by elevated dysregulation. Data were collected from 415 children with (n = 253) and without (n = 162) an older sibling with ASD, all without ASD themselves, at 18, 24, and 36 months of age. RESULTS: Our findings replicate prior reports, conducted in predominantly clinically referred and older samples, supporting the superiority of a bifactor model of the DP in the preschool period compared to the second-order and one-factor models. Examiner ratings were longitudinally and concurrently associated with the DP at 36 months of age. Family history of ASD was associated with higher dysregulation in the Anxious/Depressed dimension. CONCLUSIONS: These findings support the relevance of examining the structure of psychopathology in preschoolers and suggest that examiner observations as early as 18 months of age, particularly of overactivity, may help identify risk for later DP-related concerns. Non-ASD preschoolers with family histories of ASD may be at risk for a phenotype characterized by elevated dysregulation particularly in the Anxious/Depressed dimension by age 3. En ligne : http://dx.doi.org/10.1111/jcpp.13003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 Psychotic experiences are associated with health anxiety and functional somatic symptoms in preadolescence / M. K. RIMVALL in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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Titre : Psychotic experiences are associated with health anxiety and functional somatic symptoms in preadolescence Type de document : Texte imprimé et/ou numérique Auteurs : M. K. RIMVALL, Auteur ; C. P. JESPERSEN, Auteur ; L. CLEMMENSEN, Auteur ; A. MUNKHOLM, Auteur ; A. M. SKOVGAARD, Auteur ; F. VERHULST, Auteur ; J. VAN OS, Auteur ; C. U. RASK, Auteur ; P. JEPPESEN, Auteur Article en page(s) : p.524-532 Langues : Anglais (eng) Mots-clés : Psychosis anxiety epidemiology somatization Index. décimale : PER Périodiques Résumé : BACKGROUND: Health anxiety (HA) is an increasing public health problem related to increased health service costs, and associated with functional somatic symptoms (FSS) and considerable personal suffering. Abnormal bodily experiences which may resemble HA and FSS are common in psychotic disorders, but a potential link between HA and psychosis vulnerability in childhood is largely unexplored. The current study estimates the association between subclinical psychotic experiences (PE) and HA and FSS in a general population cohort of preadolescents. METHODS: The study population consisted of 1,572 11-12-year-old children from the Copenhagen Child Cohort 2000. PE were comprehensibly assessed as either present or not present using the Kiddie Schedule of Affective Disorders and Schizophrenia psychosis section. HA and FSS were assessed by self-report on validated questionnaires. Additional variables on general psychopathology, puberty, and chronic somatic illness were also obtained. RESULTS: Psychotic experiences were associated with the top 10% high scores of HA (Odds Ratio (OR) 3.2; 95% CI: 2.1-4.8) and FSS (OR 4.6; 95% CI: 3.1-6.9) in univariate analyses. After mutual adjustment, the association was reduced to (HA: OR 2.3; 95% CI: 1.5-3.5; FSS: OR 3.7; 95% CI: 2.4-4.7), suggesting interdependence. Further adjustment for potential confounders and general psychopathology only reduced the associations slightly: HA OR 2.2 (95% CI: 1.4-3.4); FSS OR 3.3 (95% CI: 2.1-5.2). Secondary analyses of subdimensions of HA showed that PE were associated with fears (OR 3.0; 95% CI: 2.0-4.6) and daily impact of HA symptoms (OR 5.0; 95% CI: 3.4-7.5), but not help seeking (OR 1.2; 95% CI: 0.7-2.1). CONCLUSIONS: This is the first study to investigate the associations between PE and HA and FSS, respectively. PE were significantly associated with HA and FSS over and above general psychopathology in preadolescence. Individuals with PE expressed high levels of health-related fears and daily impact, but no corresponding help-seeking behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12986 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.524-532[article] Psychotic experiences are associated with health anxiety and functional somatic symptoms in preadolescence [Texte imprimé et/ou numérique] / M. K. RIMVALL, Auteur ; C. P. JESPERSEN, Auteur ; L. CLEMMENSEN, Auteur ; A. MUNKHOLM, Auteur ; A. M. SKOVGAARD, Auteur ; F. VERHULST, Auteur ; J. VAN OS, Auteur ; C. U. RASK, Auteur ; P. JEPPESEN, Auteur . - p.524-532.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.524-532
Mots-clés : Psychosis anxiety epidemiology somatization Index. décimale : PER Périodiques Résumé : BACKGROUND: Health anxiety (HA) is an increasing public health problem related to increased health service costs, and associated with functional somatic symptoms (FSS) and considerable personal suffering. Abnormal bodily experiences which may resemble HA and FSS are common in psychotic disorders, but a potential link between HA and psychosis vulnerability in childhood is largely unexplored. The current study estimates the association between subclinical psychotic experiences (PE) and HA and FSS in a general population cohort of preadolescents. METHODS: The study population consisted of 1,572 11-12-year-old children from the Copenhagen Child Cohort 2000. PE were comprehensibly assessed as either present or not present using the Kiddie Schedule of Affective Disorders and Schizophrenia psychosis section. HA and FSS were assessed by self-report on validated questionnaires. Additional variables on general psychopathology, puberty, and chronic somatic illness were also obtained. RESULTS: Psychotic experiences were associated with the top 10% high scores of HA (Odds Ratio (OR) 3.2; 95% CI: 2.1-4.8) and FSS (OR 4.6; 95% CI: 3.1-6.9) in univariate analyses. After mutual adjustment, the association was reduced to (HA: OR 2.3; 95% CI: 1.5-3.5; FSS: OR 3.7; 95% CI: 2.4-4.7), suggesting interdependence. Further adjustment for potential confounders and general psychopathology only reduced the associations slightly: HA OR 2.2 (95% CI: 1.4-3.4); FSS OR 3.3 (95% CI: 2.1-5.2). Secondary analyses of subdimensions of HA showed that PE were associated with fears (OR 3.0; 95% CI: 2.0-4.6) and daily impact of HA symptoms (OR 5.0; 95% CI: 3.4-7.5), but not help seeking (OR 1.2; 95% CI: 0.7-2.1). CONCLUSIONS: This is the first study to investigate the associations between PE and HA and FSS, respectively. PE were significantly associated with HA and FSS over and above general psychopathology in preadolescence. Individuals with PE expressed high levels of health-related fears and daily impact, but no corresponding help-seeking behavior. En ligne : http://dx.doi.org/10.1111/jcpp.12986 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 Heterotypic trajectories of dimensional psychopathology across the lifespan: the case of youth-onset attention deficit/hyperactivity disorder / A. G. MANFRO in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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Titre : Heterotypic trajectories of dimensional psychopathology across the lifespan: the case of youth-onset attention deficit/hyperactivity disorder Type de document : Texte imprimé et/ou numérique Auteurs : A. G. MANFRO, Auteur ; M. SANTORO, Auteur ; Guilherme V. POLANCZYK, Auteur ; A. GADELHA, Auteur ; Pedro M. PAN, Auteur ; Rodrigo Affonseca BRESSAN, Auteur ; E. BRIETZKE, Auteur ; F. TALARICO, Auteur ; S. BELANGERO, Auteur ; L. A. ROHDE, Auteur ; Giovanni A. SALUM, Auteur Article en page(s) : p.533-544 Langues : Anglais (eng) Mots-clés : Youth-onset cognition executive function p-factor polygenic risk scores Index. décimale : PER Périodiques Résumé : BACKGROUND: Recent studies have demonstrated the existence of a distinct late-onset attention deficit/hyperactivity disorder (ADHD) trajectory. Our objective is to test if there are distinct ADHD trajectories regarding age of onset from childhood to adolescence and to compare clinical manifestations, cognitive functions and genetic risk for ADHD among distinct longitudinal groups. METHOD: Nine hundred and twenty four children and adolescents from the community participated in the study. We compared clinical, cognitive features and genetic risk among four groups of participants: (a) childhood-limited, (b) youth-onset, (c) childhood-onset with youth persistence, and (d) community comparisons without ADHD. Symptomatic and diagnostic assessments were performed using the Development and Well-Being Behavior Assessment, the Strengths and Difficulties Questionnaire, and the Child Behavior Checklist. Cognitive functions were measured using a battery of standardized tests. Genetic risk for ADHD was calculating using summary statistics from the Psychiatric Genomics Consortium. RESULTS: Half of the adolescents (52%) with ADHD had their symptom onset in adolescence. The impairment level of this group in adolescence is similar to the persistent group. Despite not having ADHD, the youth-onset group already presented in childhood more symptoms from other domains of psychopathology, higher shared variance in psychiatric symptomatology (p-factor), school impairment, and executive dysfunctions than community comparisons. Furthermore, the youth-onset group presented lower levels of genetic risk for ADHD compared to other cases. CONCLUSIONS: A significant proportion of adolescents with ADHD were youth-onset cases and presented similar impairment levels as those cases with early-onset ADHD. The presence of cognitive impairments and higher levels of clinical symptoms in the youth-onset group already at childhood speaks in favor of a heterotypic trajectory of psychopathology suggesting that youth-onset ADHD might be an artificial consequence of categorizing dimensional psychopathology into discrete diagnostic groups. En ligne : http://dx.doi.org/10.1111/jcpp.12987 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.533-544[article] Heterotypic trajectories of dimensional psychopathology across the lifespan: the case of youth-onset attention deficit/hyperactivity disorder [Texte imprimé et/ou numérique] / A. G. MANFRO, Auteur ; M. SANTORO, Auteur ; Guilherme V. POLANCZYK, Auteur ; A. GADELHA, Auteur ; Pedro M. PAN, Auteur ; Rodrigo Affonseca BRESSAN, Auteur ; E. BRIETZKE, Auteur ; F. TALARICO, Auteur ; S. BELANGERO, Auteur ; L. A. ROHDE, Auteur ; Giovanni A. SALUM, Auteur . - p.533-544.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.533-544
Mots-clés : Youth-onset cognition executive function p-factor polygenic risk scores Index. décimale : PER Périodiques Résumé : BACKGROUND: Recent studies have demonstrated the existence of a distinct late-onset attention deficit/hyperactivity disorder (ADHD) trajectory. Our objective is to test if there are distinct ADHD trajectories regarding age of onset from childhood to adolescence and to compare clinical manifestations, cognitive functions and genetic risk for ADHD among distinct longitudinal groups. METHOD: Nine hundred and twenty four children and adolescents from the community participated in the study. We compared clinical, cognitive features and genetic risk among four groups of participants: (a) childhood-limited, (b) youth-onset, (c) childhood-onset with youth persistence, and (d) community comparisons without ADHD. Symptomatic and diagnostic assessments were performed using the Development and Well-Being Behavior Assessment, the Strengths and Difficulties Questionnaire, and the Child Behavior Checklist. Cognitive functions were measured using a battery of standardized tests. Genetic risk for ADHD was calculating using summary statistics from the Psychiatric Genomics Consortium. RESULTS: Half of the adolescents (52%) with ADHD had their symptom onset in adolescence. The impairment level of this group in adolescence is similar to the persistent group. Despite not having ADHD, the youth-onset group already presented in childhood more symptoms from other domains of psychopathology, higher shared variance in psychiatric symptomatology (p-factor), school impairment, and executive dysfunctions than community comparisons. Furthermore, the youth-onset group presented lower levels of genetic risk for ADHD compared to other cases. CONCLUSIONS: A significant proportion of adolescents with ADHD were youth-onset cases and presented similar impairment levels as those cases with early-onset ADHD. The presence of cognitive impairments and higher levels of clinical symptoms in the youth-onset group already at childhood speaks in favor of a heterotypic trajectory of psychopathology suggesting that youth-onset ADHD might be an artificial consequence of categorizing dimensional psychopathology into discrete diagnostic groups. En ligne : http://dx.doi.org/10.1111/jcpp.12987 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 The importance of the DSM-5 posttraumatic stress disorder symptoms of cognitions and mood in traumatized children and adolescents: two network approaches / L. BARTELS in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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Titre : The importance of the DSM-5 posttraumatic stress disorder symptoms of cognitions and mood in traumatized children and adolescents: two network approaches Type de document : Texte imprimé et/ou numérique Auteurs : L. BARTELS, Auteur ; L. BERLINER, Auteur ; T. HOLT, Auteur ; T. JENSEN, Auteur ; N. JUNGBLUTH, Auteur ; P. PLENER, Auteur ; E. RISCH, Auteur ; R. ROJAS, Auteur ; R. ROSNER, Auteur ; C. SACHSER, Auteur Article en page(s) : p.545-554 Langues : Anglais (eng) Mots-clés : Dsm-5 Posttraumatic stress symptoms children and adolescents network analysis Index. décimale : PER Périodiques Résumé : BACKGROUND: The aim of this study is to provide a better understanding of the central symptoms of DSM-5 posttraumatic stress disorder (PTSD) in children and adolescents from the perspective of the child and its caregiver. Identifying core symptoms of PTSD can help clinicians to understand what may be relevant targets for treatment. PTSD may present itself differently in children and adolescents compared to adults, and no study so far has investigated the DSM-5 PTSD conceptualization using network analysis. METHODS: The network structure of DSM-5 PTSD was investigated in a clinical sample of n = 475 self-reports of children and adolescents and n = 424 caregiver-reports using (a) regularized partial correlation models and (b) a Bayesian approach computing directed acyclic graphs (DAGs). RESULTS: (a) The 20 DSM-5 PTSD symptoms were positively connected within the self-report and the caregiver-report sample. The most central symptoms were negative trauma-related cognitions and persistent negative emotional state for the self-report and negative trauma-related cognitions, intrusive thoughts or memories and exaggerated startle response for the caregiver-report. (b) Similarly, symptoms in the negative alterations in cognitions and mood cluster (NACM) have emerged as key drivers of other symptoms in traumatized children and adolescents. CONCLUSIONS: As the symptoms in the DSM-5 NACM cluster were central in our regularized partial correlation networks and also appeared to be the driving forces in the DAGs, these might represent important symptoms within PTSD symptomatology and may offer key targets in PTSD treatment for children and adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13009 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.545-554[article] The importance of the DSM-5 posttraumatic stress disorder symptoms of cognitions and mood in traumatized children and adolescents: two network approaches [Texte imprimé et/ou numérique] / L. BARTELS, Auteur ; L. BERLINER, Auteur ; T. HOLT, Auteur ; T. JENSEN, Auteur ; N. JUNGBLUTH, Auteur ; P. PLENER, Auteur ; E. RISCH, Auteur ; R. ROJAS, Auteur ; R. ROSNER, Auteur ; C. SACHSER, Auteur . - p.545-554.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.545-554
Mots-clés : Dsm-5 Posttraumatic stress symptoms children and adolescents network analysis Index. décimale : PER Périodiques Résumé : BACKGROUND: The aim of this study is to provide a better understanding of the central symptoms of DSM-5 posttraumatic stress disorder (PTSD) in children and adolescents from the perspective of the child and its caregiver. Identifying core symptoms of PTSD can help clinicians to understand what may be relevant targets for treatment. PTSD may present itself differently in children and adolescents compared to adults, and no study so far has investigated the DSM-5 PTSD conceptualization using network analysis. METHODS: The network structure of DSM-5 PTSD was investigated in a clinical sample of n = 475 self-reports of children and adolescents and n = 424 caregiver-reports using (a) regularized partial correlation models and (b) a Bayesian approach computing directed acyclic graphs (DAGs). RESULTS: (a) The 20 DSM-5 PTSD symptoms were positively connected within the self-report and the caregiver-report sample. The most central symptoms were negative trauma-related cognitions and persistent negative emotional state for the self-report and negative trauma-related cognitions, intrusive thoughts or memories and exaggerated startle response for the caregiver-report. (b) Similarly, symptoms in the negative alterations in cognitions and mood cluster (NACM) have emerged as key drivers of other symptoms in traumatized children and adolescents. CONCLUSIONS: As the symptoms in the DSM-5 NACM cluster were central in our regularized partial correlation networks and also appeared to be the driving forces in the DAGs, these might represent important symptoms within PTSD symptomatology and may offer key targets in PTSD treatment for children and adolescents. En ligne : http://dx.doi.org/10.1111/jcpp.13009 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 Course of disinhibited social engagement behavior in clinically referred home-reared preschool children / F. Y. SCHEPER in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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[article]
Titre : Course of disinhibited social engagement behavior in clinically referred home-reared preschool children Type de document : Texte imprimé et/ou numérique Auteurs : F. Y. SCHEPER, Auteur ; C. R. M. GROOT, Auteur ; A. L. C. DE VRIES, Auteur ; T. A. H. DORELEIJERS, Auteur ; L. M. C. JANSEN, Auteur ; C. SCHUENGEL, Auteur Article en page(s) : p.555-565 Langues : Anglais (eng) Mots-clés : Disinhibited social engagement attachment home-reared longitudinal preschool Index. décimale : PER Périodiques Résumé : BACKGROUND: Evidence supporting clinical relevance and persistence of disinhibited social engagement behavior (DSEB) pertains mostly to children reared in institutions and foster care. This study examined the course of DSEB in clinically referred home-reared children from early into middle childhood, and associations with neglect/emotional maltreatment, effortful control, Attention Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, and Autism Spectrum Disorder. METHODS: Disinhibited social engagement behavior was examined in 124 children (82% boys, M = 4.06 years, SD = 0.89), referred for treatment of emotional and behavioral problems, by use of the Disturbances of Attachment Interview (DAI) with biological parents. Neglect and emotional maltreatment were assessed from case records and effortful control by use of the Child Behavior Questionnaire. At follow-up, on average 4 years later, DSEB was examined by use of DAI as well as two observational ratings: the Stranger at the Door procedure (SatD) and a structured home observation of stranger approach. Psychiatric disorders were assessed by means of the Kiddie-Schedule for Affective Disorders and Schizophrenia. RESULTS: Persistence of parent-reported DSEB was found in 57% (n = 27) of the children with DSEB at baseline (n = 47). Parent-reported DSEB at follow-up was significantly related to DSEB observed in the SatD (rpb = .31, p = .001) and to observed stranger approach (rs = .41, p < .001), but only stranger approach was associated with baseline DSEB. The course of DSEB was not related to neglect/emotional maltreatment, nor to the level of effortful control. There was no association between DSEB and Autism Spectrum Disorder, but course of DSEB was associated with Attention Deficit/Hyperactivity Disorder/Oppositional Defiant Disorder at follow-up (chi(2) = 13.08, p = .004). CONCLUSIONS: Although explanations for the onset and course of DSEB in home-reared children remain elusive, findings suggest that DSEB is part of a complex of clinically significant problem behaviors in referred home-reared preschool children. En ligne : http://dx.doi.org/10.1111/jcpp.12994 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.555-565[article] Course of disinhibited social engagement behavior in clinically referred home-reared preschool children [Texte imprimé et/ou numérique] / F. Y. SCHEPER, Auteur ; C. R. M. GROOT, Auteur ; A. L. C. DE VRIES, Auteur ; T. A. H. DORELEIJERS, Auteur ; L. M. C. JANSEN, Auteur ; C. SCHUENGEL, Auteur . - p.555-565.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.555-565
Mots-clés : Disinhibited social engagement attachment home-reared longitudinal preschool Index. décimale : PER Périodiques Résumé : BACKGROUND: Evidence supporting clinical relevance and persistence of disinhibited social engagement behavior (DSEB) pertains mostly to children reared in institutions and foster care. This study examined the course of DSEB in clinically referred home-reared children from early into middle childhood, and associations with neglect/emotional maltreatment, effortful control, Attention Deficit/Hyperactivity Disorder, Oppositional Defiant Disorder, and Autism Spectrum Disorder. METHODS: Disinhibited social engagement behavior was examined in 124 children (82% boys, M = 4.06 years, SD = 0.89), referred for treatment of emotional and behavioral problems, by use of the Disturbances of Attachment Interview (DAI) with biological parents. Neglect and emotional maltreatment were assessed from case records and effortful control by use of the Child Behavior Questionnaire. At follow-up, on average 4 years later, DSEB was examined by use of DAI as well as two observational ratings: the Stranger at the Door procedure (SatD) and a structured home observation of stranger approach. Psychiatric disorders were assessed by means of the Kiddie-Schedule for Affective Disorders and Schizophrenia. RESULTS: Persistence of parent-reported DSEB was found in 57% (n = 27) of the children with DSEB at baseline (n = 47). Parent-reported DSEB at follow-up was significantly related to DSEB observed in the SatD (rpb = .31, p = .001) and to observed stranger approach (rs = .41, p < .001), but only stranger approach was associated with baseline DSEB. The course of DSEB was not related to neglect/emotional maltreatment, nor to the level of effortful control. There was no association between DSEB and Autism Spectrum Disorder, but course of DSEB was associated with Attention Deficit/Hyperactivity Disorder/Oppositional Defiant Disorder at follow-up (chi(2) = 13.08, p = .004). CONCLUSIONS: Although explanations for the onset and course of DSEB in home-reared children remain elusive, findings suggest that DSEB is part of a complex of clinically significant problem behaviors in referred home-reared preschool children. En ligne : http://dx.doi.org/10.1111/jcpp.12994 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 Pubertal recalibration of cortisol reactivity following early life stress: a cross-sectional analysis / Carrie E. DEPASQUALE in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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[article]
Titre : Pubertal recalibration of cortisol reactivity following early life stress: a cross-sectional analysis Type de document : Texte imprimé et/ou numérique Auteurs : Carrie E. DEPASQUALE, Auteur ; B. DONZELLA, Auteur ; M. R. GUNNAR, Auteur Article en page(s) : p.566-575 Langues : Anglais (eng) Mots-clés : Stress endocrinology institutions puberty Index. décimale : PER Périodiques Résumé : BACKGROUND: Children adopted from orphanages or other such institutions tend to display blunted reactivity to stressors - even years after arriving in their generally supportive and highly resourced postadoption homes. Puberty, a proposed sensitive period for environmental influences on stress-mediating systems, may provide an opportunity for postinstitutionalized children to recalibrate stress response systems in accordance with their now more supportive living situations. METHODS: This cross-sectional study examined the hypothalamic-pituitary-adrenocortical (HPA)-axis reactivity of 280 children ages 7 through 14 years; 122 children were adopted from institutions in 14 countries between the ages of 6 months and 5 years, after spending an average of 95% of their lives in institutional care, and 158 children of similarly high socioeconomic status in their biological families served as the nonadopted comparison group. All of the children were assessed by nurses for Tanner stage and, on a different day, completed the Trier Social Stress Test for Children. RESULTS: Using a linear mixed-effects model and seven measures of salivary cortisol, results indicated that early-pubertal postinstitutionalized children showed blunted HPA axis reactivity compared to nonadopted children, but mid/late-pubertal postinstitutionalized children displayed higher reactivity similar to the nonadopted comparison children. CONCLUSIONS: This is the first evidence of possible pubertal recalibration of HPA axis reactivity to a psychosocial stressor in postinstitutionalized children, which provides a promising avenue for future research regarding the protective factors of the postadoption environment and subsequent physiological, behavioral, and psychopathological outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.12992 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.566-575[article] Pubertal recalibration of cortisol reactivity following early life stress: a cross-sectional analysis [Texte imprimé et/ou numérique] / Carrie E. DEPASQUALE, Auteur ; B. DONZELLA, Auteur ; M. R. GUNNAR, Auteur . - p.566-575.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.566-575
Mots-clés : Stress endocrinology institutions puberty Index. décimale : PER Périodiques Résumé : BACKGROUND: Children adopted from orphanages or other such institutions tend to display blunted reactivity to stressors - even years after arriving in their generally supportive and highly resourced postadoption homes. Puberty, a proposed sensitive period for environmental influences on stress-mediating systems, may provide an opportunity for postinstitutionalized children to recalibrate stress response systems in accordance with their now more supportive living situations. METHODS: This cross-sectional study examined the hypothalamic-pituitary-adrenocortical (HPA)-axis reactivity of 280 children ages 7 through 14 years; 122 children were adopted from institutions in 14 countries between the ages of 6 months and 5 years, after spending an average of 95% of their lives in institutional care, and 158 children of similarly high socioeconomic status in their biological families served as the nonadopted comparison group. All of the children were assessed by nurses for Tanner stage and, on a different day, completed the Trier Social Stress Test for Children. RESULTS: Using a linear mixed-effects model and seven measures of salivary cortisol, results indicated that early-pubertal postinstitutionalized children showed blunted HPA axis reactivity compared to nonadopted children, but mid/late-pubertal postinstitutionalized children displayed higher reactivity similar to the nonadopted comparison children. CONCLUSIONS: This is the first evidence of possible pubertal recalibration of HPA axis reactivity to a psychosocial stressor in postinstitutionalized children, which provides a promising avenue for future research regarding the protective factors of the postadoption environment and subsequent physiological, behavioral, and psychopathological outcomes. En ligne : http://dx.doi.org/10.1111/jcpp.12992 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 Child maltreatment in autism spectrum disorder and intellectual disability: results from a population-based sample / C. G. MCDONNELL in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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[article]
Titre : Child maltreatment in autism spectrum disorder and intellectual disability: results from a population-based sample Type de document : Texte imprimé et/ou numérique Auteurs : C. G. MCDONNELL, Auteur ; Andrea BOAN, Auteur ; Catherine BRADLEY, Auteur ; K. D. SEAY, Auteur ; J. M. CHARLES, Auteur ; Laura A. CARPENTER, Auteur Article en page(s) : p.576-584 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder child maltreatment intellectual disability Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with developmental disabilities are at heightened risk for maltreatment. However, little is known regarding the prevalence of maltreatment among specific groups, such as autism spectrum disorder (ASD) and/or intellectual disability (ID). Information about maltreatment in these groups can aid in the development of supports and prevention strategies for vulnerable children and their families. METHODS: Using record linkage between the Department of Social Services (DSS) and the Autism and Developmental Disabilities Monitoring (ADDM) network, this study compares the prevalence and characteristics of maltreatment among children with ASD-only (n = 316), ASD and comorbid ID (ASD+ID; n = 291), ID-only (n = 1,280), and controls (n = 3,101). Behavioral correlates of maltreatment are examined. RESULTS: Controlling for demographic factors, this study found significantly higher odds of reported and substantiated maltreatment among children with ASD-only (odds ratio = 1.86 for reported, 1.51 for substantiated), ASD+ID (odds ratio = 2.35 for reported, 1.97 for substantiated), and ID-only (odds ratio = 2.45 for reported, 2.49 for substantiated) relative to a population control group, with large effects. In particular, children with ASD+ID and ID-only were between two and three times more likely to experience maltreatment. All groups were more likely to experience physical neglect, and children in the ASD+ID and ID-only groups were more likely to experience all forms of abuse. Children in the ASD-only group were more likely to experience physical abuse. Maltreated children in the ASD-only and ID-only groups experienced more cases of physical abuse and neglect, and were victimized by more perpetrators compared to other maltreated youth. Maltreatment was associated with higher likelihood of aggression, hyperactivity, and tantrums for children with ASD. CONCLUSIONS: Children with ASD and/or ID are at heightened risk for maltreatment. Empirically-supported assessment and intervention approaches for identifying and addressing traumatic stress related to maltreatment in ASD are urgently needed. En ligne : http://dx.doi.org/10.1111/jcpp.12993 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.576-584[article] Child maltreatment in autism spectrum disorder and intellectual disability: results from a population-based sample [Texte imprimé et/ou numérique] / C. G. MCDONNELL, Auteur ; Andrea BOAN, Auteur ; Catherine BRADLEY, Auteur ; K. D. SEAY, Auteur ; J. M. CHARLES, Auteur ; Laura A. CARPENTER, Auteur . - p.576-584.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.576-584
Mots-clés : Autism spectrum disorder child maltreatment intellectual disability Index. décimale : PER Périodiques Résumé : BACKGROUND: Children with developmental disabilities are at heightened risk for maltreatment. However, little is known regarding the prevalence of maltreatment among specific groups, such as autism spectrum disorder (ASD) and/or intellectual disability (ID). Information about maltreatment in these groups can aid in the development of supports and prevention strategies for vulnerable children and their families. METHODS: Using record linkage between the Department of Social Services (DSS) and the Autism and Developmental Disabilities Monitoring (ADDM) network, this study compares the prevalence and characteristics of maltreatment among children with ASD-only (n = 316), ASD and comorbid ID (ASD+ID; n = 291), ID-only (n = 1,280), and controls (n = 3,101). Behavioral correlates of maltreatment are examined. RESULTS: Controlling for demographic factors, this study found significantly higher odds of reported and substantiated maltreatment among children with ASD-only (odds ratio = 1.86 for reported, 1.51 for substantiated), ASD+ID (odds ratio = 2.35 for reported, 1.97 for substantiated), and ID-only (odds ratio = 2.45 for reported, 2.49 for substantiated) relative to a population control group, with large effects. In particular, children with ASD+ID and ID-only were between two and three times more likely to experience maltreatment. All groups were more likely to experience physical neglect, and children in the ASD+ID and ID-only groups were more likely to experience all forms of abuse. Children in the ASD-only group were more likely to experience physical abuse. Maltreated children in the ASD-only and ID-only groups experienced more cases of physical abuse and neglect, and were victimized by more perpetrators compared to other maltreated youth. Maltreatment was associated with higher likelihood of aggression, hyperactivity, and tantrums for children with ASD. CONCLUSIONS: Children with ASD and/or ID are at heightened risk for maltreatment. Empirically-supported assessment and intervention approaches for identifying and addressing traumatic stress related to maltreatment in ASD are urgently needed. En ligne : http://dx.doi.org/10.1111/jcpp.12993 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 Integrative network analysis reveals biological pathways associated with Williams syndrome in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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[article]
Titre : Integrative network analysis reveals biological pathways associated with Williams syndrome Type de document : Texte imprimé et/ou numérique Article en page(s) : p.585-598 Langues : Anglais (eng) Mots-clés : Williams syndrome autism spectrum disorder genetics Index. décimale : PER Périodiques Résumé : BACKGROUND: Williams syndrome (WS) is a neurodevelopmental disorder that has been attributed to heterozygous deletions in chromosome 7q11.23 and exhibits a variety of physical, cognitive, and behavioral features. However, the genetic basis of this phenotypic variability is unclear. In this study, we identified genetic clues underlying these complex phenotypes. METHODS: Neurobehavioral function was assessed in WS patients and healthy controls. Total RNA was extracted from peripheral blood and subjected to microarray analysis, RNA-sequencing, and qRT-PCR. Weighted gene co-expression network analysis was performed to identify specific alterations related to intermediate disease phenotypes. To functionally interpret each WS-related module, gene ontology and disease-related gene enrichment were examined. We also investigated the micro (mi)RNA expression profiles and miRNA co-expression networks to better explain the regulation of the transcriptome in WS. RESULTS: Our analysis identified four significant co-expression modules related to intermediate WS phenotypes. Notably, the three upregulated WS-related modules were composed exclusively of genes located outside the 7q11.23 region. They were significantly enriched in genes related to B-cell activation, RNA processing, and RNA transport. BCL11A, which is known for its association with speech disorders and intellectual disabilities, was identified as one of the hub genes in the top WS-related module. Finally, these key upregulated mRNA co-expression modules appear to be inversely correlated with a specific downregulated WS-related miRNA co-expression module. CONCLUSIONS: Dysregulation of the mRNA/miRNA network involving genes outside of the 7q11.23 region is likely related to the complex phenotypes observed in WS patients. En ligne : http://dx.doi.org/10.1111/jcpp.12999 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.585-598[article] Integrative network analysis reveals biological pathways associated with Williams syndrome [Texte imprimé et/ou numérique] . - p.585-598.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.585-598
Mots-clés : Williams syndrome autism spectrum disorder genetics Index. décimale : PER Périodiques Résumé : BACKGROUND: Williams syndrome (WS) is a neurodevelopmental disorder that has been attributed to heterozygous deletions in chromosome 7q11.23 and exhibits a variety of physical, cognitive, and behavioral features. However, the genetic basis of this phenotypic variability is unclear. In this study, we identified genetic clues underlying these complex phenotypes. METHODS: Neurobehavioral function was assessed in WS patients and healthy controls. Total RNA was extracted from peripheral blood and subjected to microarray analysis, RNA-sequencing, and qRT-PCR. Weighted gene co-expression network analysis was performed to identify specific alterations related to intermediate disease phenotypes. To functionally interpret each WS-related module, gene ontology and disease-related gene enrichment were examined. We also investigated the micro (mi)RNA expression profiles and miRNA co-expression networks to better explain the regulation of the transcriptome in WS. RESULTS: Our analysis identified four significant co-expression modules related to intermediate WS phenotypes. Notably, the three upregulated WS-related modules were composed exclusively of genes located outside the 7q11.23 region. They were significantly enriched in genes related to B-cell activation, RNA processing, and RNA transport. BCL11A, which is known for its association with speech disorders and intellectual disabilities, was identified as one of the hub genes in the top WS-related module. Finally, these key upregulated mRNA co-expression modules appear to be inversely correlated with a specific downregulated WS-related miRNA co-expression module. CONCLUSIONS: Dysregulation of the mRNA/miRNA network involving genes outside of the 7q11.23 region is likely related to the complex phenotypes observed in WS patients. En ligne : http://dx.doi.org/10.1111/jcpp.12999 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392 Commentary: "Autism: a disorder linked with some trouble in intermodal matching? Putting things together a bit further": a commentary on Falck-Ytter et al. (2018) / A. GUEDENEY in Journal of Child Psychology and Psychiatry, 60-5 (May 2019)
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[article]
Titre : Commentary: "Autism: a disorder linked with some trouble in intermodal matching? Putting things together a bit further": a commentary on Falck-Ytter et al. (2018) Type de document : Texte imprimé et/ou numérique Auteurs : A. GUEDENEY, Auteur Article en page(s) : p.599-601 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Falck-Ytter et al. () (Journal of Child Psychology and Psychiatry 59: 872-880) designed an elegant study with 10-month-old siblings of children with autism using an eye-tracking task. En ligne : http://dx.doi.org/10.1111/jcpp.13056 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.599-601[article] Commentary: "Autism: a disorder linked with some trouble in intermodal matching? Putting things together a bit further": a commentary on Falck-Ytter et al. (2018) [Texte imprimé et/ou numérique] / A. GUEDENEY, Auteur . - p.599-601.
Langues : Anglais (eng)
in Journal of Child Psychology and Psychiatry > 60-5 (May 2019) . - p.599-601
Index. décimale : PER Périodiques Résumé : Falck-Ytter et al. () (Journal of Child Psychology and Psychiatry 59: 872-880) designed an elegant study with 10-month-old siblings of children with autism using an eye-tracking task. En ligne : http://dx.doi.org/10.1111/jcpp.13056 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=392