[article] 
inJournal of Autism and Developmental Disorders > 54-3 (March 2024) . - p.1143-1156

Titre :	Retinal Thinning in Adults with Autism Spectrum Disorder
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Evelyn B. N. FRIEDEL, Auteur ; Ludger TEBARTZ VAN ELST, Auteur ; Mirjam SCHAFER, Auteur ; Simon MAIER, Auteur ; Kimon RUNGE, Auteur ; Sebastian KÜCHLIN, Auteur ; Michael REICH, Auteur ; Wolf A. LAGRÈZE, Auteur ; Jürgen KORNMEIER, Auteur ; Dieter EBERT, Auteur ; Dominique ENDRES, Auteur ; Katharina DOMSCHKE, Auteur ; Kathrin NICKEL, Auteur
Article en page(s) :	p.1143-1156
Langues :	Anglais (eng)
Index. décimale :	PER Périodiques
Résumé :	Since the retina shares its embryological origin with the central nervous system, optical coherence tomography (OCT), an imaging technique frequently employed in ophthalmology to analyze the macula and intraretinal layer thicknesses and volumes, has recently become increasingly important in psychiatric research. We examined 34 autistic and 31 neurotypical adults (NT) using OCT. Autistic adults had reduced overall macular and outer nuclear layer (ONL) thickness and volume compared to NT. Both macular and ONL thickness showed significant inverse associations with the severity of autistic symptoms measured with the Social Responsiveness Scale 2 (SRS-2). Longitudinal studies across different age groups are required to clarify whether retinal changes may represent a possible trait marker.
En ligne :	https://doi.org/10.1007/s10803-022-05882-8
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=524

[article] Retinal Thinning in Adults with Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Evelyn B. N. FRIEDEL, Auteur ; Ludger TEBARTZ VAN ELST, Auteur ; Mirjam SCHAFER, Auteur ; Simon MAIER, Auteur ; Kimon RUNGE, Auteur ; Sebastian KÜCHLIN, Auteur ; Michael REICH, Auteur ; Wolf A. LAGRÈZE, Auteur ; Jürgen KORNMEIER, Auteur ; Dieter EBERT, Auteur ; Dominique ENDRES, Auteur ; Katharina DOMSCHKE, Auteur ; Kathrin NICKEL, Auteur . - p.1143-1156.
Langues : Anglais (eng)
in Journal of Autism and Developmental Disorders > 54-3 (March 2024) . - p.1143-1156

Index. décimale :	PER Périodiques
Résumé :	Since the retina shares its embryological origin with the central nervous system, optical coherence tomography (OCT), an imaging technique frequently employed in ophthalmology to analyze the macula and intraretinal layer thicknesses and volumes, has recently become increasingly important in psychiatric research. We examined 34 autistic and 31 neurotypical adults (NT) using OCT. Autistic adults had reduced overall macular and outer nuclear layer (ONL) thickness and volume compared to NT. Both macular and ONL thickness showed significant inverse associations with the severity of autistic symptoms measured with the Social Responsiveness Scale 2 (SRS-2). Longitudinal studies across different age groups are required to clarify whether retinal changes may represent a possible trait marker.
En ligne :	https://doi.org/10.1007/s10803-022-05882-8
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=524