[article] 
inDevelopment and Psychopathology > 36-4 (October 2024) . - p.1638-1652

Titre :	Biobehavioral mechanisms underlying testosterone and mood relationships in peripubertal female adolescents
Type de document :	Texte imprimé et/ou numérique
Auteurs :	Elizabeth ANDERSEN, Auteur ; Julianna PRIM, Auteur ; Alana CAMPBELL, Auteur ; Crystal SCHILLER, Auteur ; Kayla BARESICH, Auteur ; Susan GIRDLER, Auteur
Article en page(s) :	p.1638-1652
Langues :	Anglais (eng)
Mots-clés :	EEG  negative affect  peripuberty  stress  testosterone
Index. décimale :	PER Périodiques
Résumé :	The pubertal transition is characterized by pronounced sex hormone fluctuation, refinement of affective neural circuitry, and an increased risk of depression in female adolescents. Sex hormones, including testosterone, exert modulatory effects on frontal-limbic brain networks and are associated with emotion dysregulation and depressive symptoms. Weekly changes in hormones predict affective symptoms in peripubertal female adolescents, particularly in the context of stress; however, the biobehavioral mechanisms underlying hormone change and mood relationships during the pubertal transition have yet to be determined and was the objective of the present study. Forty-three peripubertal female adolescents (ages 11-14) collected 8-weekly salivary hormone (estrone, testosterone) samples and mood assessments to evaluate hormone-mood relationships, followed by a biobehavioral testing session with psychosocial stress and EEG. Within-person correlations between weekly hormone changes and corresponding mood were performed to determine individual differences in mood sensitivity to weekly hormone change. Increased frontal theta activity indexing emotion reactivity, reduced cortisol reactivity, and reduced vagal efficiency predicted the strength of the relationship between testosterone and mood. Further, testosterone-sensitivity strength was associated with the enhancement of negative affect following stress testing. Results identify divergent frontal theta and stress responses as potential biobehavioral mechanisms underlying mood sensitivity to peripubertal testosterone fluctuation.
En ligne :	https://dx.doi.org/10.1017/S0954579423000937
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539

[article] Biobehavioral mechanisms underlying testosterone and mood relationships in peripubertal female adolescents [Texte imprimé et/ou numérique] / Elizabeth ANDERSEN, Auteur ; Julianna PRIM, Auteur ; Alana CAMPBELL, Auteur ; Crystal SCHILLER, Auteur ; Kayla BARESICH, Auteur ; Susan GIRDLER, Auteur . - p.1638-1652.
Langues : Anglais (eng)
in Development and Psychopathology > 36-4 (October 2024) . - p.1638-1652

Mots-clés :	EEG  negative affect  peripuberty  stress  testosterone
Index. décimale :	PER Périodiques
Résumé :	The pubertal transition is characterized by pronounced sex hormone fluctuation, refinement of affective neural circuitry, and an increased risk of depression in female adolescents. Sex hormones, including testosterone, exert modulatory effects on frontal-limbic brain networks and are associated with emotion dysregulation and depressive symptoms. Weekly changes in hormones predict affective symptoms in peripubertal female adolescents, particularly in the context of stress; however, the biobehavioral mechanisms underlying hormone change and mood relationships during the pubertal transition have yet to be determined and was the objective of the present study. Forty-three peripubertal female adolescents (ages 11-14) collected 8-weekly salivary hormone (estrone, testosterone) samples and mood assessments to evaluate hormone-mood relationships, followed by a biobehavioral testing session with psychosocial stress and EEG. Within-person correlations between weekly hormone changes and corresponding mood were performed to determine individual differences in mood sensitivity to weekly hormone change. Increased frontal theta activity indexing emotion reactivity, reduced cortisol reactivity, and reduced vagal efficiency predicted the strength of the relationship between testosterone and mood. Further, testosterone-sensitivity strength was associated with the enhancement of negative affect following stress testing. Results identify divergent frontal theta and stress responses as potential biobehavioral mechanisms underlying mood sensitivity to peripubertal testosterone fluctuation.
En ligne :	https://dx.doi.org/10.1017/S0954579423000937
Permalink :	https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=539