Transdiagnostic pathways from early social stress to psychopathology: a 20-year prospective study / C. C. CONWAY in Journal of Child Psychology and Psychiatry, 59-8 (August 2018)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 59-8 (August 2018) . - p.855-862 Titre : Transdiagnostic pathways from early social stress to psychopathology: a 20-year prospective study Type de document : Texte imprimé et/ou numérique Auteurs : C. C. CONWAY, Auteur ; E. B. RAPOSA, Auteur ; C. HAMMEN, Auteur ; Patricia A. BRENNAN, Auteur Article en page(s) : p.855-862 Langues : Anglais (eng) Mots-clés : Classification  comorbidity  early adversity  stress  transdiagnostic Index. décimale : PER Périodiques Résumé : BACKGROUND: Adverse family environments confer susceptibility to virtually all psychiatric problems. This study evaluated two possible models to explain this diversity of associations. Stressful family circumstances during childhood could either activate general, transdiagnostic liabilities to mental disorder or promote numerous disorder-specific liabilities. METHODS: We recruited a high-risk sample of 815 mother-offspring pairs and assessed social stressors in the family context prospectively from the perinatal period through offspring age 5. We factor analyzed offspring mental disorder diagnoses at age 20 to parse transdiagnostic and disorder-specific dimensions of psychopathology. RESULTS: Structural analyses revealed nearly equivalent prospective effects of early family stress on overarching Internalizing (beta = .30) and Externalizing (beta = .29) dimensions. In contrast, there was no evidence of disorder-specific effects. CONCLUSIONS: Social stressors early in life activate transdiagnostic, and not disorder-specific, liabilities to psychopathology. A focus on higher-order dimensions of psychopathology could accelerate etiological research and intervention efforts for stress-linked mental disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12862 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 [article] Transdiagnostic pathways from early social stress to psychopathology: a 20-year prospective study [Texte imprimé et/ou numérique] / C. C. CONWAY, Auteur ; E. B. RAPOSA, Auteur ; C. HAMMEN, Auteur ; Patricia A. BRENNAN, Auteur . - p.855-862. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 59-8 (August 2018) . - p.855-862 Mots-clés : Classification  comorbidity  early adversity  stress  transdiagnostic Index. décimale : PER Périodiques Résumé : BACKGROUND: Adverse family environments confer susceptibility to virtually all psychiatric problems. This study evaluated two possible models to explain this diversity of associations. Stressful family circumstances during childhood could either activate general, transdiagnostic liabilities to mental disorder or promote numerous disorder-specific liabilities. METHODS: We recruited a high-risk sample of 815 mother-offspring pairs and assessed social stressors in the family context prospectively from the perinatal period through offspring age 5. We factor analyzed offspring mental disorder diagnoses at age 20 to parse transdiagnostic and disorder-specific dimensions of psychopathology. RESULTS: Structural analyses revealed nearly equivalent prospective effects of early family stress on overarching Internalizing (beta = .30) and Externalizing (beta = .29) dimensions. In contrast, there was no evidence of disorder-specific effects. CONCLUSIONS: Social stressors early in life activate transdiagnostic, and not disorder-specific, liabilities to psychopathology. A focus on higher-order dimensions of psychopathology could accelerate etiological research and intervention efforts for stress-linked mental disorders. En ligne : http://dx.doi.org/10.1111/jcpp.12862 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368

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