
- <Centre d'Information et de documentation du CRA Rhône-Alpes
- CRA
- Informations pratiques
-
Adresse
Centre d'information et de documentation
Horaires
du CRA Rhône-Alpes
Centre Hospitalier le Vinatier
bât 211
95, Bd Pinel
69678 Bron CedexLundi au Vendredi
Contact
9h00-12h00 13h30-16h00Tél: +33(0)4 37 91 54 65
Mail
Fax: +33(0)4 37 91 54 37
-
Adresse
Détail de l'auteur
Auteur Yu ZHANG |
Documents disponibles écrits par cet auteur (2)



Head circumference, body growth and development quotient in autism spectrum disorders are related in Chongqing, China / Hua WEI in Research in Autism Spectrum Disorders, 54 (October 2018)
![]()
[article]
Titre : Head circumference, body growth and development quotient in autism spectrum disorders are related in Chongqing, China Type de document : Texte imprimé et/ou numérique Auteurs : Hua WEI, Auteur ; Qian CHENG, Auteur ; Qixia MEI, Auteur ; Xuan ZHANG, Auteur ; Li CHEN, Auteur ; Xiao LIU, Auteur ; Ying DAI, Auteur ; Ting YU, Auteur ; Yan LI, Auteur ; Yu ZHANG, Auteur ; Jie CHEN, Auteur ; Yongjie MIAO, Auteur ; Tingyu LI, Auteur Article en page(s) : p.83-89 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Head circumference Body height Body weight Development quotient Index. décimale : PER Périodiques Résumé : Background It is unclear whether increased head circumference (HC) is actually an artifact of an overall overgrowth phenomenon or specific to the brain at all in autism spectrum disorders. This study compared the head circumferences, body weight and height of ASD children with a control group. We also discuss whether HC, body weight and height are correlated with development quotients in ASD children. Method We recruited 83 children with ASD (aged 2–5 years); they were gender and age matched to typically developing children in Chongqing (China) from 2013 to 2015. Their head circumference, body weight and height were collected. The ASD group was tested for the developmental quotient (DQ), which includes gross motor, fine motor, linguistic, personal-social and adaptive functioning. Results Our results showed that head circumference in the ASD group is significantly different from HC in the control group. The rate of macrocephaly was higher in the children with ASD compared with the control group. Some domains of DQ have statistically significant negative correlation with head circumference, weight and height. After adjusting for confounding factors, the fine motor was associated negatively with HC. Personal-social ability was associated negatively with weight. Gross motor was correlated negatively with the height. Conclusions Based on our results, we found significant HC differences in ASD group while lack of effect of either height or weight at the age of 2–5. HC, weight and height were separately negative correlated with some domains of development quotients. Further research is needed to understand the relationship between physical indicators and development level in autism. En ligne : https://doi.org/10.1016/j.rasd.2018.07.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368
in Research in Autism Spectrum Disorders > 54 (October 2018) . - p.83-89[article] Head circumference, body growth and development quotient in autism spectrum disorders are related in Chongqing, China [Texte imprimé et/ou numérique] / Hua WEI, Auteur ; Qian CHENG, Auteur ; Qixia MEI, Auteur ; Xuan ZHANG, Auteur ; Li CHEN, Auteur ; Xiao LIU, Auteur ; Ying DAI, Auteur ; Ting YU, Auteur ; Yan LI, Auteur ; Yu ZHANG, Auteur ; Jie CHEN, Auteur ; Yongjie MIAO, Auteur ; Tingyu LI, Auteur . - p.83-89.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 54 (October 2018) . - p.83-89
Mots-clés : Autism spectrum disorder Head circumference Body height Body weight Development quotient Index. décimale : PER Périodiques Résumé : Background It is unclear whether increased head circumference (HC) is actually an artifact of an overall overgrowth phenomenon or specific to the brain at all in autism spectrum disorders. This study compared the head circumferences, body weight and height of ASD children with a control group. We also discuss whether HC, body weight and height are correlated with development quotients in ASD children. Method We recruited 83 children with ASD (aged 2–5 years); they were gender and age matched to typically developing children in Chongqing (China) from 2013 to 2015. Their head circumference, body weight and height were collected. The ASD group was tested for the developmental quotient (DQ), which includes gross motor, fine motor, linguistic, personal-social and adaptive functioning. Results Our results showed that head circumference in the ASD group is significantly different from HC in the control group. The rate of macrocephaly was higher in the children with ASD compared with the control group. Some domains of DQ have statistically significant negative correlation with head circumference, weight and height. After adjusting for confounding factors, the fine motor was associated negatively with HC. Personal-social ability was associated negatively with weight. Gross motor was correlated negatively with the height. Conclusions Based on our results, we found significant HC differences in ASD group while lack of effect of either height or weight at the age of 2–5. HC, weight and height were separately negative correlated with some domains of development quotients. Further research is needed to understand the relationship between physical indicators and development level in autism. En ligne : https://doi.org/10.1016/j.rasd.2018.07.003 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=368 Retrospective analysis of the correlation between serum vitamin D levels and blood amino acids levels in children with autism: Exploration of possible mechanisms of the effect of vitamin D on autism / Bing WANG in Research in Autism Spectrum Disorders, 80 (February 2021)
![]()
[article]
Titre : Retrospective analysis of the correlation between serum vitamin D levels and blood amino acids levels in children with autism: Exploration of possible mechanisms of the effect of vitamin D on autism Type de document : Texte imprimé et/ou numérique Auteurs : Bing WANG, Auteur ; Hanyu DONG, Auteur ; Junyan FENG, Auteur ; Honghua LI, Auteur ; Yu ZHANG, Auteur ; Feiyong JIA, Auteur ; Lin XIE, Auteur Article en page(s) : p.101707 Langues : Anglais (eng) Mots-clés : Autism spectrum disorder Vitamin D Amino acid Biological metabolism Index. décimale : PER Périodiques Résumé : Hypovitaminosis D has been recognized as a risk factor for autism spectrum disorder (ASD); however, its mechanism remains unclear. Amino acid metabolism is involved in the related factors of ASD, such as neurotransmitters, oxidative stress, and immune dysfunction. Vitamin D not only regulates the activity of the amino acid transport system, but is also closely related to amino acids in the regulation of immunity and oxidative stress. To investigate the possible mechanisms by which vitamin D may influence ASD, the correlation between blood amino acids and serum 25(OH)D levels of 506 children (411 males and 95 females) with ASD were retrospectively analyzed, and possible related pathways were determined via a literature review. According to the results, alanine, arginine, glycine, ornithine, glutamine and histidine were found to be significantly negatively correlated with serum 25(OH)D levels (P?0.05). Glycine and ornithine were also found to be influenced by age, and glutamine levels were different in male and female children with ASD. In addition, there were differences in alanine levels in different BMI levels. However, after adjusting for the influences of these factors in the regression equation, it was found that 25(OH)D was associated with the identified 6 amino acids (P?0.05). Therefore, vitamin D may influence ASD through the cross-pathways of these amino acids (i.e. glutamine-gamma aminobutyric acid balance, oxidative stress, and immune dysfunction). This conclusion may provide some ideas for further investigation of the effect of vitamin D on ASD. En ligne : https://doi.org/10.1016/j.rasd.2020.101707 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438
in Research in Autism Spectrum Disorders > 80 (February 2021) . - p.101707[article] Retrospective analysis of the correlation between serum vitamin D levels and blood amino acids levels in children with autism: Exploration of possible mechanisms of the effect of vitamin D on autism [Texte imprimé et/ou numérique] / Bing WANG, Auteur ; Hanyu DONG, Auteur ; Junyan FENG, Auteur ; Honghua LI, Auteur ; Yu ZHANG, Auteur ; Feiyong JIA, Auteur ; Lin XIE, Auteur . - p.101707.
Langues : Anglais (eng)
in Research in Autism Spectrum Disorders > 80 (February 2021) . - p.101707
Mots-clés : Autism spectrum disorder Vitamin D Amino acid Biological metabolism Index. décimale : PER Périodiques Résumé : Hypovitaminosis D has been recognized as a risk factor for autism spectrum disorder (ASD); however, its mechanism remains unclear. Amino acid metabolism is involved in the related factors of ASD, such as neurotransmitters, oxidative stress, and immune dysfunction. Vitamin D not only regulates the activity of the amino acid transport system, but is also closely related to amino acids in the regulation of immunity and oxidative stress. To investigate the possible mechanisms by which vitamin D may influence ASD, the correlation between blood amino acids and serum 25(OH)D levels of 506 children (411 males and 95 females) with ASD were retrospectively analyzed, and possible related pathways were determined via a literature review. According to the results, alanine, arginine, glycine, ornithine, glutamine and histidine were found to be significantly negatively correlated with serum 25(OH)D levels (P?0.05). Glycine and ornithine were also found to be influenced by age, and glutamine levels were different in male and female children with ASD. In addition, there were differences in alanine levels in different BMI levels. However, after adjusting for the influences of these factors in the regression equation, it was found that 25(OH)D was associated with the identified 6 amino acids (P?0.05). Therefore, vitamin D may influence ASD through the cross-pathways of these amino acids (i.e. glutamine-gamma aminobutyric acid balance, oxidative stress, and immune dysfunction). This conclusion may provide some ideas for further investigation of the effect of vitamin D on ASD. En ligne : https://doi.org/10.1016/j.rasd.2020.101707 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=438