[article]
| Titre : |
Early-stage randomised controlled trial of therapist-supported online cognitive therapy for post-traumatic stress disorder in young people |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Patrick SMITH, Auteur ; Anke EHLERS, Auteur ; Ewan CARR, Auteur ; David M. CLARK, Auteur ; Tim DALGLEISH, Auteur ; Gordon FORBES, Auteur ; Kimberley GOLDSMITH, Auteur ; Helena GRIFFITHS, Auteur ; Monica GUPTA, Auteur ; Dorothy KING, Auteur ; Sarah MILES, Auteur ; Dominic T. PLANT, Auteur ; Anne SMITH, Auteur ; Jess STEWARD, Auteur ; William YULE, Auteur ; Richard MEISER-STEDMAN, Auteur |
| Article en page(s) : |
p.1117-1128 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Post-traumatic stress disorder adolescence cognitive therapy E-health Randomised Controlled Trial |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Background Effective face-to-face treatments for Post-Traumatic Stress Disorder (PTSD) are available, but most young people with PTSD do not receive effective treatment. Therapist-supported online Cognitive Therapy has the potential to improve accessibility of effective treatment. This early-stage trial gathered data on the feasibility, acceptability, and initial signal of clinical efficacy of a novel online Cognitive Therapy program for young people with PTSD. Methods A two-arm, parallel-groups, single-blind, early-stage feasibility RCT compared online Cognitive Therapy to a waitlList condition. Participants were N?=?31 adolescents (12?17?years-old) with a diagnosis of PTSD, randomised in a 1:1 ratio using minimisation. Thresholds for progression to a larger trial were set a priori for recruitment rate, data completeness, and the initial signal of clinical efficacy. The primary clinical outcome was PTSD diagnosis at 16?weeks post-randomisation. Secondary clinical outcomes were continuous measures of PTSD, depression, and anxiety at 16?weeks; and at 38?weeks in the online Cognitive Therapy arm. Results All pre-determined feasibility thresholds for progression to a larger trial were met. We recruited to target at a rate of 1?2 participants/month. No patient dropped out of therapy; 94% of all participants were retained at 16?weeks. At 16-weeks, the intention-to-treat (ITT) effect adjusted odds ratio was 0.20 (95% CI, 0.02, 1.42), indicating that the odds of meeting PTSD caseness after online therapy were 80% lower than after the waitlist (10/16 participants met PTSD caseness after therapy compared to 11/13 after WL). Effect-size estimates for all secondary clinical outcomes were large-moderate; improvements were sustained 38?weeks after online Cognitive Therapy. Conclusions Therapist-supported online Cognitive Therapy for PTSD is acceptable to young people and has potential for meaningful and sustained clinical effects. A larger trial appears feasible to deliver. Further work is needed to refine the intervention and its delivery and to evaluate it in a larger confirmatory trial. |
| En ligne : |
https://doi.org/10.1111/jcpp.14124 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=564 |
in Journal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1117-1128
[article] Early-stage randomised controlled trial of therapist-supported online cognitive therapy for post-traumatic stress disorder in young people [Texte imprimé et/ou numérique] / Patrick SMITH, Auteur ; Anke EHLERS, Auteur ; Ewan CARR, Auteur ; David M. CLARK, Auteur ; Tim DALGLEISH, Auteur ; Gordon FORBES, Auteur ; Kimberley GOLDSMITH, Auteur ; Helena GRIFFITHS, Auteur ; Monica GUPTA, Auteur ; Dorothy KING, Auteur ; Sarah MILES, Auteur ; Dominic T. PLANT, Auteur ; Anne SMITH, Auteur ; Jess STEWARD, Auteur ; William YULE, Auteur ; Richard MEISER-STEDMAN, Auteur . - p.1117-1128. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 66-8 (August 2025) . - p.1117-1128
| Mots-clés : |
Post-traumatic stress disorder adolescence cognitive therapy E-health Randomised Controlled Trial |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Background Effective face-to-face treatments for Post-Traumatic Stress Disorder (PTSD) are available, but most young people with PTSD do not receive effective treatment. Therapist-supported online Cognitive Therapy has the potential to improve accessibility of effective treatment. This early-stage trial gathered data on the feasibility, acceptability, and initial signal of clinical efficacy of a novel online Cognitive Therapy program for young people with PTSD. Methods A two-arm, parallel-groups, single-blind, early-stage feasibility RCT compared online Cognitive Therapy to a waitlList condition. Participants were N?=?31 adolescents (12?17?years-old) with a diagnosis of PTSD, randomised in a 1:1 ratio using minimisation. Thresholds for progression to a larger trial were set a priori for recruitment rate, data completeness, and the initial signal of clinical efficacy. The primary clinical outcome was PTSD diagnosis at 16?weeks post-randomisation. Secondary clinical outcomes were continuous measures of PTSD, depression, and anxiety at 16?weeks; and at 38?weeks in the online Cognitive Therapy arm. Results All pre-determined feasibility thresholds for progression to a larger trial were met. We recruited to target at a rate of 1?2 participants/month. No patient dropped out of therapy; 94% of all participants were retained at 16?weeks. At 16-weeks, the intention-to-treat (ITT) effect adjusted odds ratio was 0.20 (95% CI, 0.02, 1.42), indicating that the odds of meeting PTSD caseness after online therapy were 80% lower than after the waitlist (10/16 participants met PTSD caseness after therapy compared to 11/13 after WL). Effect-size estimates for all secondary clinical outcomes were large-moderate; improvements were sustained 38?weeks after online Cognitive Therapy. Conclusions Therapist-supported online Cognitive Therapy for PTSD is acceptable to young people and has potential for meaningful and sustained clinical effects. A larger trial appears feasible to deliver. Further work is needed to refine the intervention and its delivery and to evaluate it in a larger confirmatory trial. |
| En ligne : |
https://doi.org/10.1111/jcpp.14124 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=564 |
|
Early-stage randomised controlled trial of therapist-supported online cognitive therapy for post-traumatic stress disorder in young people in Journal of Child Psychology and Psychiatry, 66-8 (August 2025)
