Reduced Bone Cortical Thickness in Boys with Autism or Autism Spectrum Disorder / Mary L. HEDIGER in Journal of Autism and Developmental Disorders, 38-5 (May 2008)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 38-5 (May 2008) . - p.848-856 Titre : Reduced Bone Cortical Thickness in Boys with Autism or Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Mary L. HEDIGER, Auteur ; Patricia MANNING-COURTNEY, Auteur ; Lucinda J. ENGLAND, Auteur ; Cynthia A. MOLLOY, Auteur ; Kai F. YU, Auteur ; James L. MILLS, Auteur Année de publication : 2008 Article en page(s) : p.848-856 Langues : Anglais (eng) Mots-clés : Autism Autism-spectrum-disorder Boys Bone-growth Calcium-intake Dietary-intake Index. décimale : PER Périodiques Résumé : Bone development, casein-free diet use, supplements, and medications were assessed for 75 boys with autism or autism spectrum disorder, ages 4–8 years. Second metacarpal bone cortical thickness (BCT), measured on hand-wrist radiographs, and % deviations in BCT from reference medians were derived. BCT increased with age, but % deviations evidenced a progressive fall-off (p = .02): +3.1 ± 4.7%, −6.5 ± 4.0%, −16.6 ± 3.4%, −19.4 ± 3.7%, −24.1 ± 4.4%, at ages 4–8, respectively, adjusting for height. The 12% of the boys on casein-free diets had an overall % deviation of −18.9 ± 3.7%, nearly twice that of boys on minimally restricted or unrestricted diets (−10.5 ± 1.3%, p < .04), although even for boys on minimally restricted or unrestricted diets the % deviation was highly significant (p < .001). Our data suggest that the bone development of autistic boys should be monitored as part of routine care, especially if they are on casein-free diets. En ligne : http://dx.doi.org/10.1007/s10803-007-0453-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416 [article] Reduced Bone Cortical Thickness in Boys with Autism or Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Mary L. HEDIGER, Auteur ; Patricia MANNING-COURTNEY, Auteur ; Lucinda J. ENGLAND, Auteur ; Cynthia A. MOLLOY, Auteur ; Kai F. YU, Auteur ; James L. MILLS, Auteur . - 2008 . - p.848-856. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 38-5 (May 2008) . - p.848-856 Mots-clés : Autism Autism-spectrum-disorder Boys Bone-growth Calcium-intake Dietary-intake Index. décimale : PER Périodiques Résumé : Bone development, casein-free diet use, supplements, and medications were assessed for 75 boys with autism or autism spectrum disorder, ages 4–8 years. Second metacarpal bone cortical thickness (BCT), measured on hand-wrist radiographs, and % deviations in BCT from reference medians were derived. BCT increased with age, but % deviations evidenced a progressive fall-off (p = .02): +3.1 ± 4.7%, −6.5 ± 4.0%, −16.6 ± 3.4%, −19.4 ± 3.7%, −24.1 ± 4.4%, at ages 4–8, respectively, adjusting for height. The 12% of the boys on casein-free diets had an overall % deviation of −18.9 ± 3.7%, nearly twice that of boys on minimally restricted or unrestricted diets (−10.5 ± 1.3%, p < .04), although even for boys on minimally restricted or unrestricted diets the % deviation was highly significant (p < .001). Our data suggest that the bone development of autistic boys should be monitored as part of routine care, especially if they are on casein-free diets. En ligne : http://dx.doi.org/10.1007/s10803-007-0453-6 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=416

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