[article]
| Titre : |
An Investigation of Age-related Neuropathophysiology in Autism Spectrum Disorder Using Fixel-based Analysis of Corpus Callosum White Matter Micro- and Macrostructure |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Melissa KIRKOVSKI, Auteur ; Mervyn SINGH, Auteur ; Thijs DHOLLANDER, Auteur ; Ian FUELSCHER, Auteur ; Christian HYDE, Auteur ; Natalia ALBEIN-URIOS, Auteur ; Peter H. DONALDSON, Auteur ; Peter G. ENTICOTT, Auteur |
| Article en page(s) : |
p.2198-2210 |
| Langues : |
Anglais (eng) |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Fixel-based analysis was used to probe age-related changes in white matter micro- and macrostructure of the corpus callosum between participants with (N = 54) and without (N = 50) autism spectrum disorder (ASD). Data were obtained from the Autism Brain Imaging Data Exchange-II (ABIDE-II). Compared to age-matched controls, young adolescents with ASD (11.19?+?7.54 years) showed reduced macroscopic fiber cross-section (logFC) and combined fiber-density and cross-section (FDC). Reduced fiber-density (FD) and FDC was noted in a marginally older (13.87?+?3.15 years) ASD cohort. Among the oldest ASD cohort (17.07?+?3.56 years), a non-significant trend indicative of reduced FD was noted. White matter aberration appears greatest and most widespread among younger ASD cohorts. This supports the suggestion that some early neuropathophysiological indicators in ASD may dissipate with age. |
| En ligne : |
https://doi.org/10.1007/s10803-023-05980-1 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=530 |
in Journal of Autism and Developmental Disorders > 54-6 (June 2024) . - p.2198-2210
[article] An Investigation of Age-related Neuropathophysiology in Autism Spectrum Disorder Using Fixel-based Analysis of Corpus Callosum White Matter Micro- and Macrostructure [Texte imprimé et/ou numérique] / Melissa KIRKOVSKI, Auteur ; Mervyn SINGH, Auteur ; Thijs DHOLLANDER, Auteur ; Ian FUELSCHER, Auteur ; Christian HYDE, Auteur ; Natalia ALBEIN-URIOS, Auteur ; Peter H. DONALDSON, Auteur ; Peter G. ENTICOTT, Auteur . - p.2198-2210. Langues : Anglais ( eng) in Journal of Autism and Developmental Disorders > 54-6 (June 2024) . - p.2198-2210
| Index. décimale : |
PER Périodiques |
| Résumé : |
Fixel-based analysis was used to probe age-related changes in white matter micro- and macrostructure of the corpus callosum between participants with (N = 54) and without (N = 50) autism spectrum disorder (ASD). Data were obtained from the Autism Brain Imaging Data Exchange-II (ABIDE-II). Compared to age-matched controls, young adolescents with ASD (11.19?+?7.54 years) showed reduced macroscopic fiber cross-section (logFC) and combined fiber-density and cross-section (FDC). Reduced fiber-density (FD) and FDC was noted in a marginally older (13.87?+?3.15 years) ASD cohort. Among the oldest ASD cohort (17.07?+?3.56 years), a non-significant trend indicative of reduced FD was noted. White matter aberration appears greatest and most widespread among younger ASD cohorts. This supports the suggestion that some early neuropathophysiological indicators in ASD may dissipate with age. |
| En ligne : |
https://doi.org/10.1007/s10803-023-05980-1 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=530 |
|
Faire une suggestion Affiner la rechercheAn Investigation of Age-related Neuropathophysiology in Autism Spectrum Disorder Using Fixel-based Analysis of Corpus Callosum White Matter Micro- and Macrostructure / Melissa KIRKOVSKI in Journal of Autism and Developmental Disorders, 54-6 (June 2024)
Research and Treatment Applications of Transcranial Direct Current Stimulation (tDCS) in Autism Spectrum Disorder / Dinisha PARMAR
