Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review / Seema JAIN in Journal of Autism and Developmental Disorders, 46-4 (April 2016)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 46-4 (April 2016) . - p.1344-1353 Titre : Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review Type de document : texte imprimé Auteurs : Seema JAIN, Auteur ; Rebecca R. ANDRIDGE, Auteur ; Jessica A. HELLINGS, Auteur Article en page(s) : p.1344-1353 Langues : Anglais (eng) Mots-clés : Loxapine  Metabolic side effects  Autism spectrum disorder  Atypical antipsychotics Index. décimale : PER Périodiques Résumé : Loxapine substitution is a promising option for patients with autism spectrum disorder (ASD) who develop antipsychotic-induced metabolic illness. We performed a chart review of 15 adolescents and adults meeting DSM-IV-TR criteria for ASD, all with antipsychotic-associated weight gain, who received low dose loxapine in an attempt to taper or discontinue the weight gain-associated antipsychotic. Mean weight loss was −5.7 kg, mean BMI reduction was −1.9, and mean triglyceride reduction was −33.7 mg/dl. At chart review, 14 of 15 subjects were rated 2 (Much Improved) or 1 (Very Much Improved) on the Clinical Global Impressions-Improvement scale (CGI-I). Low dose loxapine addition in most cases enabled taper of offending antipsychotics, significantly reversed drug-induced metabolic disturbances and improved irritability. En ligne : http://dx.doi.org/10.1007/s10803-015-2675-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=284 [article] Loxapine for Reversal of Antipsychotic-Induced Metabolic Disturbances: A Chart Review [texte imprimé] / Seema JAIN, Auteur ; Rebecca R. ANDRIDGE, Auteur ; Jessica A. HELLINGS, Auteur . - p.1344-1353. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 46-4 (April 2016) . - p.1344-1353 Mots-clés : Loxapine  Metabolic side effects  Autism spectrum disorder  Atypical antipsychotics Index. décimale : PER Périodiques Résumé : Loxapine substitution is a promising option for patients with autism spectrum disorder (ASD) who develop antipsychotic-induced metabolic illness. We performed a chart review of 15 adolescents and adults meeting DSM-IV-TR criteria for ASD, all with antipsychotic-associated weight gain, who received low dose loxapine in an attempt to taper or discontinue the weight gain-associated antipsychotic. Mean weight loss was −5.7 kg, mean BMI reduction was −1.9, and mean triglyceride reduction was −33.7 mg/dl. At chart review, 14 of 15 subjects were rated 2 (Much Improved) or 1 (Very Much Improved) on the Clinical Global Impressions-Improvement scale (CGI-I). Low dose loxapine addition in most cases enabled taper of offending antipsychotics, significantly reversed drug-induced metabolic disturbances and improved irritability. En ligne : http://dx.doi.org/10.1007/s10803-015-2675-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=284

Shakespeare and Autism: A Pilot Study Examining the Treatment Effects and Predictors of Treatment Response of the Hunter Heartbeat Method / Margaret H. MEHLING in Autism - Open Access, 7-5 ([01/10/2017])  

Public ISBD [article]  inAutism - Open Access > 7-5 [01/10/2017] . - 9 p. Titre : Shakespeare and Autism: A Pilot Study Examining the Treatment Effects and Predictors of Treatment Response of the Hunter Heartbeat Method Type de document : texte imprimé Auteurs : Margaret H. MEHLING, Auteur ; Marc J. TASSE, Auteur ; Rebecca R. ANDRIDGE, Auteur Article en page(s) : 9 p. Langues : Anglais (eng) Mots-clés : Autism spectrum disorder  Intervention  Social skills  Drama-based  Hunter heartbeat method  Shakespeare Index. décimale : PER Périodiques Résumé : This pilot study was designed to explore the potential impact of participation in the Hunter Heartbeat Method, adrama-based social skills intervention, on the core symptoms of autism spectrum disorder (ASD). A sample of 10children with ASD participated in this study. Children were assessed at three time-points: before the start of the intervention (T1), after 14 weeks of participation (T2) and after 42 weeks of participation (T3). Findings from this pilot study indicated that the Hunter Heartbeat Method (HHM) is an intervention that shows promise in impacting social, communication and facial emotion recognition deficits associated with ASD. We also identified the individual characteristics of the participants who were responders and non-responders to the HHM intervention. The results of these findings are discussed. En ligne : https://dx.doi.org/10.4172/2165-7890.1000222 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=410 [article] Shakespeare and Autism: A Pilot Study Examining the Treatment Effects and Predictors of Treatment Response of the Hunter Heartbeat Method [texte imprimé] / Margaret H. MEHLING, Auteur ; Marc J. TASSE, Auteur ; Rebecca R. ANDRIDGE, Auteur . - 9 p. Langues : Anglais (eng) in Autism - Open Access > 7-5 [01/10/2017] . - 9 p. Mots-clés : Autism spectrum disorder  Intervention  Social skills  Drama-based  Hunter heartbeat method  Shakespeare Index. décimale : PER Périodiques Résumé : This pilot study was designed to explore the potential impact of participation in the Hunter Heartbeat Method, adrama-based social skills intervention, on the core symptoms of autism spectrum disorder (ASD). A sample of 10children with ASD participated in this study. Children were assessed at three time-points: before the start of the intervention (T1), after 14 weeks of participation (T2) and after 42 weeks of participation (T3). Findings from this pilot study indicated that the Hunter Heartbeat Method (HHM) is an intervention that shows promise in impacting social, communication and facial emotion recognition deficits associated with ASD. We also identified the individual characteristics of the participants who were responders and non-responders to the HHM intervention. The results of these findings are discussed. En ligne : https://dx.doi.org/10.4172/2165-7890.1000222 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=410

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