Early behavioral profiles elucidating vulnerability and resiliency to later ASD outcomes / Rebecca J. LANDA in Development and Psychopathology, 32-4 (October 2020)  

Public ISBD [article]  inDevelopment and Psychopathology > 32-4 (October 2020) . - p.1217-1229 Titre : Early behavioral profiles elucidating vulnerability and resiliency to later ASD outcomes Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca J. LANDA, Auteur ; Rachel REETZKE, Auteur ; Madiha TAHSEEN, Auteur ; Christine Reiner HESS, Auteur Article en page(s) : p.1217-1229 Langues : Anglais (eng) Mots-clés : autism spectrum disorder  high-risk siblings  resilience  symptomology  vulnerability Index. décimale : PER Périodiques Résumé : Infant siblings of children with autism spectrum disorder (ASD) exhibit greater heterogeneity in behavioral presentation and outcomes relative to infants at low familial risk (LR), yet there is limited understanding of the diverse developmental profiles that characterize these infants. We applied a hierarchical agglomerative cluster analysis approach to parse developmental heterogeneity in 420 toddlers with heightened (HR) and low (LR) familial risk for ASD using measures of four dimensions of development: language, social, play, and restricted and repetitive behaviors (RRB). Results revealed a two-cluster solution. Comparisons of clusters revealed significantly lower language, social, and play performance, and higher levels of restricted and repetitive behaviors in Cluster 1 relative to Cluster 2. In Cluster 1, 25% of children were later diagnosed with ASD compared to 8% in Cluster 2. Comparisons within Cluster 1 between subgroups of toddlers having ASD+ versus ASD- 36-month outcomes revealed significantly lower functioning in the ASD+ subgroup across cognitive, motor, social, language, symbolic, and speech dimensions. Findings suggest profiles of early development associated with resiliency and vulnerability to later ASD diagnosis, with multidimensional developmental lags signaling vulnerability to ASD diagnosis. En ligne : http://dx.doi.org/10.1017/s0954579420000814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433 [article] Early behavioral profiles elucidating vulnerability and resiliency to later ASD outcomes [Texte imprimé et/ou numérique] / Rebecca J. LANDA, Auteur ; Rachel REETZKE, Auteur ; Madiha TAHSEEN, Auteur ; Christine Reiner HESS, Auteur . - p.1217-1229. Langues : Anglais (eng) in Development and Psychopathology > 32-4 (October 2020) . - p.1217-1229 Mots-clés : autism spectrum disorder  high-risk siblings  resilience  symptomology  vulnerability Index. décimale : PER Périodiques Résumé : Infant siblings of children with autism spectrum disorder (ASD) exhibit greater heterogeneity in behavioral presentation and outcomes relative to infants at low familial risk (LR), yet there is limited understanding of the diverse developmental profiles that characterize these infants. We applied a hierarchical agglomerative cluster analysis approach to parse developmental heterogeneity in 420 toddlers with heightened (HR) and low (LR) familial risk for ASD using measures of four dimensions of development: language, social, play, and restricted and repetitive behaviors (RRB). Results revealed a two-cluster solution. Comparisons of clusters revealed significantly lower language, social, and play performance, and higher levels of restricted and repetitive behaviors in Cluster 1 relative to Cluster 2. In Cluster 1, 25% of children were later diagnosed with ASD compared to 8% in Cluster 2. Comparisons within Cluster 1 between subgroups of toddlers having ASD+ versus ASD- 36-month outcomes revealed significantly lower functioning in the ASD+ subgroup across cognitive, motor, social, language, symbolic, and speech dimensions. Findings suggest profiles of early development associated with resiliency and vulnerability to later ASD diagnosis, with multidimensional developmental lags signaling vulnerability to ASD diagnosis. En ligne : http://dx.doi.org/10.1017/s0954579420000814 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=433

Infant Achievements Intervention Improves Caregiver Implementation Fidelity and Infant Social Communication Outcomes: A Preliminary Randomized Clinical Trial / Rachel REETZKE ; Christine Reiner HESS in Autism Research, 18-5 (May 2025)  

Public ISBD [article]  inAutism Research > 18-5 (May 2025) . - p.1104-1116 Titre : Infant Achievements Intervention Improves Caregiver Implementation Fidelity and Infant Social Communication Outcomes: A Preliminary Randomized Clinical Trial Type de document : Texte imprimé et/ou numérique Auteurs : Rachel REETZKE, Auteur ; Christine Reiner HESS, Auteur Article en page(s) : p.1104-1116 Langues : Anglais (eng) Mots-clés : caregiver  communication  delay  infants  intervention  randomized controlled trial  social Index. décimale : PER Périodiques Résumé : ABSTRACT Randomized controlled trials (RCTs) focused on idiopathic social communication delay (SCD) in the first year of life are rare. We preliminarily tested the efficacy of an 8-week caregiver-implemented intervention for infants with idiopathic SCD. Infants (8?12?months) with SCD were block-randomized with caregivers to the Infant Achievements (IA) (n?=?18) or Caregiver Education (CE) (n?=?20) group in this assessor-masked RCT. Assessments were completed at baseline, post-intervention, and 8-week follow-up. IA caregivers received reflective, home-based coaching to implement naturalistic developmental behavioral intervention (NDBI) strategies. Primary outcomes: masked ratings of caregiver implementation fidelity, frequency of infant initiation of joint attention (IJA), and percent of coordination of joint engagement (CJE). Secondary outcomes: masked researcher-administered and scored Mullen Scales of Early Learning (MSEL) language and Visual Reception scaled scores; nonmasked caregiver-reported Communication and Symbolic Behavior Scales Caregiver Questionnaire (CSBS CQ) Social, Speech, and Symbolic composite scores and McArthur-Bates Communication Development Inventories Words Understood and Produced scores. Prespecified analyses followed an intent-to-treat approach using Generalized Linear Mixed Models for non-normally distributed outcomes and linear mixed-effects models for those with normal distributions. Significant group by time effects favored the IA group relative to the CE group on all primary outcomes at post-intervention (p's???0.001), and for caregiver fidelity and IJA, at follow-up (??0.03). Significant IA intervention effects were detected on secondary outcomes of nonverbal cognition (MSEL Visual Reception) and CSBS CQ Speech composite at post-intervention ( En ligne : https://doi.org/10.1002/aur.70051 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=558 [article] Infant Achievements Intervention Improves Caregiver Implementation Fidelity and Infant Social Communication Outcomes: A Preliminary Randomized Clinical Trial [Texte imprimé et/ou numérique] / Rachel REETZKE, Auteur ; Christine Reiner HESS, Auteur . - p.1104-1116. Langues : Anglais (eng) in Autism Research > 18-5 (May 2025) . - p.1104-1116 Mots-clés : caregiver  communication  delay  infants  intervention  randomized controlled trial  social Index. décimale : PER Périodiques Résumé : ABSTRACT Randomized controlled trials (RCTs) focused on idiopathic social communication delay (SCD) in the first year of life are rare. We preliminarily tested the efficacy of an 8-week caregiver-implemented intervention for infants with idiopathic SCD. Infants (8?12?months) with SCD were block-randomized with caregivers to the Infant Achievements (IA) (n?=?18) or Caregiver Education (CE) (n?=?20) group in this assessor-masked RCT. Assessments were completed at baseline, post-intervention, and 8-week follow-up. IA caregivers received reflective, home-based coaching to implement naturalistic developmental behavioral intervention (NDBI) strategies. Primary outcomes: masked ratings of caregiver implementation fidelity, frequency of infant initiation of joint attention (IJA), and percent of coordination of joint engagement (CJE). Secondary outcomes: masked researcher-administered and scored Mullen Scales of Early Learning (MSEL) language and Visual Reception scaled scores; nonmasked caregiver-reported Communication and Symbolic Behavior Scales Caregiver Questionnaire (CSBS CQ) Social, Speech, and Symbolic composite scores and McArthur-Bates Communication Development Inventories Words Understood and Produced scores. Prespecified analyses followed an intent-to-treat approach using Generalized Linear Mixed Models for non-normally distributed outcomes and linear mixed-effects models for those with normal distributions. Significant group by time effects favored the IA group relative to the CE group on all primary outcomes at post-intervention (p's???0.001), and for caregiver fidelity and IJA, at follow-up (??0.03). Significant IA intervention effects were detected on secondary outcomes of nonverbal cognition (MSEL Visual Reception) and CSBS CQ Speech composite at post-intervention ( En ligne : https://doi.org/10.1002/aur.70051 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=558

---

1 (1 - 2 / 2)