ADHD medication adherence reduces risk of committing minor offenses in adolescents / Paul T. ROSENAU in Journal of Child Psychology and Psychiatry, 65-11 (November 2024)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 65-11 (November 2024) . - p.1478-1485 Titre : ADHD medication adherence reduces risk of committing minor offenses in adolescents Type de document : Texte imprimé et/ou numérique Auteurs : Paul T. ROSENAU, Auteur ; Andrea DIETRICH, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Pieter J. HOEKSTRA, Auteur Article en page(s) : p.1478-1485 Langues : Anglais (eng) Mots-clés : Adolescents  ADHD medication  risk reduction  crime  survival analysis Index. décimale : PER Périodiques Résumé : Background This study aimed to investigate the association between adolescents? adherence to attention-deficit/hyperactivity disorder (ADHD) medication and their risk of committing minor offenses. Methods Using two Dutch databases, Statistics Netherlands (CBS) and the Foundation for Pharmaceutical Statistics (SFK), we aimed to investigate the association between adherence to ADHD medication and registered minor offenses between 2005 and 2019 of 18,234 adolescents (12?18?years). We used Cox regression analyses to compare the rate of committing minor offenses of adolescents during periods of high ADHD medication adherence compared to periods of low adherence (i.e., periods with or without sufficient amounts of dispensed medication). We additionally tested associations with adherence to selective serotonin reuptake inhibitors (SSRIs) as control medication and analyzed potential reverse causation. Results High ADHD medication adherence was associated with a reduced risk of committing a minor offense of between 33% and 38% compared to low adherence periods of ?3?months (hazard ratio [HR] 0.67, confidence interval [CI] 0.64?0.71) or ?6?months (HR 0.62, CI 0.59?0.65). The reduction in risk can likely be attributed to ADHD medication, given the absence of effects of SSRIs and no reverse causation. The reduction rate remained between 16% and 55% per sex, stimulant versus non-stimulant medication, different offense categories and further sensitivity analyses. Conclusions Among adolescents using ADHD medication, rates of criminality were lower during periods of high medication adherence, suggesting that adherence to ADHD medication may contribute to prevention of minor offenses in adolescents. En ligne : https://doi.org/10.1111/jcpp.13997 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=537 [article] ADHD medication adherence reduces risk of committing minor offenses in adolescents [Texte imprimé et/ou numérique] / Paul T. ROSENAU, Auteur ; Andrea DIETRICH, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Pieter J. HOEKSTRA, Auteur . - p.1478-1485. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 65-11 (November 2024) . - p.1478-1485 Mots-clés : Adolescents  ADHD medication  risk reduction  crime  survival analysis Index. décimale : PER Périodiques Résumé : Background This study aimed to investigate the association between adolescents? adherence to attention-deficit/hyperactivity disorder (ADHD) medication and their risk of committing minor offenses. Methods Using two Dutch databases, Statistics Netherlands (CBS) and the Foundation for Pharmaceutical Statistics (SFK), we aimed to investigate the association between adherence to ADHD medication and registered minor offenses between 2005 and 2019 of 18,234 adolescents (12?18?years). We used Cox regression analyses to compare the rate of committing minor offenses of adolescents during periods of high ADHD medication adherence compared to periods of low adherence (i.e., periods with or without sufficient amounts of dispensed medication). We additionally tested associations with adherence to selective serotonin reuptake inhibitors (SSRIs) as control medication and analyzed potential reverse causation. Results High ADHD medication adherence was associated with a reduced risk of committing a minor offense of between 33% and 38% compared to low adherence periods of ?3?months (hazard ratio [HR] 0.67, confidence interval [CI] 0.64?0.71) or ?6?months (HR 0.62, CI 0.59?0.65). The reduction in risk can likely be attributed to ADHD medication, given the absence of effects of SSRIs and no reverse causation. The reduction rate remained between 16% and 55% per sex, stimulant versus non-stimulant medication, different offense categories and further sensitivity analyses. Conclusions Among adolescents using ADHD medication, rates of criminality were lower during periods of high medication adherence, suggesting that adherence to ADHD medication may contribute to prevention of minor offenses in adolescents. En ligne : https://doi.org/10.1111/jcpp.13997 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=537

Early-Life Environmental and Child Factors Associated with the Presence of Disruptive Behaviors in Seven-Year-Old Children with Autistic Traits in the Avon Longitudinal Study of Parents and Children / Simone BREIDER in Journal of Autism and Developmental Disorders, 52-6 (June 2022)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2747-2761 Titre : Early-Life Environmental and Child Factors Associated with the Presence of Disruptive Behaviors in Seven-Year-Old Children with Autistic Traits in the Avon Longitudinal Study of Parents and Children Type de document : Texte imprimé et/ou numérique Auteurs : Simone BREIDER, Auteur ; Pieter J. HOEKSTRA, Auteur ; Klaas J. WARDENAAR, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Andrea DIETRICH, Auteur ; Annelies DE BILDT, Auteur Article en page(s) : p.2747-2761 Langues : Anglais (eng) Mots-clés : Alspac  Autism spectrum disorder  Disruptive behaviors  Early-life  Environmental  Risk factors Index. décimale : PER Périodiques Résumé : We studied the association of early-life environmental and child factors with disruptive behaviors in children with autistic traits around age 7, in the Avon Longitudinal Study of Parents and Children (n=6,401). Logistic regression with the least absolute shrinkage and selection operator indicated that disruptive behaviors were associated with prenatal smoking, no seafood-consumption during pregnancy, breech presentation at delivery, neonatal feeding problems, low social-economic situation, suboptimal preschool family environment, maternal depression, maternal antisocial behavior, male sex, and difficult child temperament. Compared to controls, male sex, maternal depression, and suboptimal preschool family environment were related to autistic traits without disruptive behaviors. Thus, there may be a difference in early-life factors related to autism spectrum disorder with and without disruptive behaviors. En ligne : http://dx.doi.org/10.1007/s10803-021-05081-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474 [article] Early-Life Environmental and Child Factors Associated with the Presence of Disruptive Behaviors in Seven-Year-Old Children with Autistic Traits in the Avon Longitudinal Study of Parents and Children [Texte imprimé et/ou numérique] / Simone BREIDER, Auteur ; Pieter J. HOEKSTRA, Auteur ; Klaas J. WARDENAAR, Auteur ; Barbara J. VAN DEN HOOFDAKKER, Auteur ; Andrea DIETRICH, Auteur ; Annelies DE BILDT, Auteur . - p.2747-2761. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 52-6 (June 2022) . - p.2747-2761 Mots-clés : Alspac  Autism spectrum disorder  Disruptive behaviors  Early-life  Environmental  Risk factors Index. décimale : PER Périodiques Résumé : We studied the association of early-life environmental and child factors with disruptive behaviors in children with autistic traits around age 7, in the Avon Longitudinal Study of Parents and Children (n=6,401). Logistic regression with the least absolute shrinkage and selection operator indicated that disruptive behaviors were associated with prenatal smoking, no seafood-consumption during pregnancy, breech presentation at delivery, neonatal feeding problems, low social-economic situation, suboptimal preschool family environment, maternal depression, maternal antisocial behavior, male sex, and difficult child temperament. Compared to controls, male sex, maternal depression, and suboptimal preschool family environment were related to autistic traits without disruptive behaviors. Thus, there may be a difference in early-life factors related to autism spectrum disorder with and without disruptive behaviors. En ligne : http://dx.doi.org/10.1007/s10803-021-05081-x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=474

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