[article]
| Titre : |
Reward-related decision-making in pediatric major depressive disorder: an fMRI study |
| Type de document : |
texte imprimé |
| Auteurs : |
Erika E. FORBES, Auteur ; Boris BIRMAHER, Auteur ; David A. AXELSON, Auteur ; J. Christopher MAY, Auteur ; Greg J. SIEGLE, Auteur ; Cecile D. LADOUCEUR, Auteur ; Neal D. RYAN, Auteur ; Cameron S. CARTER, Auteur ; Ronald E. DAHL, Auteur |
| Année de publication : |
2007 |
| Article en page(s) : |
p.1031–1040 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Depression reward decision-making |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Background: Although reward processing is considered an important part of affective functioning, few studies have investigated reward-related decisions or responses in young people with affective disorders. Depression is postulated to involve decreased activity in reward-related affective systems.
Methods: Using functional magnetic resonance imaging (fMRI), we examined behavioral and neural responses to reward in young people with depressive disorders using a reward decision-making task. The task involved choices about possible rewards involving varying magnitude and probability of reward. The study design allowed the separation of decision/anticipation and outcome phases of reward processing. Participants were 9–17 years old and had diagnoses of major depressive disorder (MDD), anxiety disorders, or no history of psychiatric disorder.
Results: Participants with MDD exhibited less neural response than control participants in reward-related brain areas during both phases of the task. Group differences did not appear to be a function of anxiety. Depressive and anxiety symptoms were associated with activation in reward-related brain areas.
Conclusions: Results suggest that depression involves altered reward processing and underscore the need for further investigation of relations among development, affective disorders, and reward processing. |
| En ligne : |
http://dx.doi.org/10.1111/j.1469-7610.2006.01673.x |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=793 |
in Journal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.1031–1040
[article] Reward-related decision-making in pediatric major depressive disorder: an fMRI study [texte imprimé] / Erika E. FORBES, Auteur ; Boris BIRMAHER, Auteur ; David A. AXELSON, Auteur ; J. Christopher MAY, Auteur ; Greg J. SIEGLE, Auteur ; Cecile D. LADOUCEUR, Auteur ; Neal D. RYAN, Auteur ; Cameron S. CARTER, Auteur ; Ronald E. DAHL, Auteur . - 2007 . - p.1031–1040. Langues : Anglais ( eng) in Journal of Child Psychology and Psychiatry > 47-10 (October 2006) . - p.1031–1040
| Mots-clés : |
Depression reward decision-making |
| Index. décimale : |
PER Périodiques |
| Résumé : |
Background: Although reward processing is considered an important part of affective functioning, few studies have investigated reward-related decisions or responses in young people with affective disorders. Depression is postulated to involve decreased activity in reward-related affective systems.
Methods: Using functional magnetic resonance imaging (fMRI), we examined behavioral and neural responses to reward in young people with depressive disorders using a reward decision-making task. The task involved choices about possible rewards involving varying magnitude and probability of reward. The study design allowed the separation of decision/anticipation and outcome phases of reward processing. Participants were 9–17 years old and had diagnoses of major depressive disorder (MDD), anxiety disorders, or no history of psychiatric disorder.
Results: Participants with MDD exhibited less neural response than control participants in reward-related brain areas during both phases of the task. Group differences did not appear to be a function of anxiety. Depressive and anxiety symptoms were associated with activation in reward-related brain areas.
Conclusions: Results suggest that depression involves altered reward processing and underscore the need for further investigation of relations among development, affective disorders, and reward processing. |
| En ligne : |
http://dx.doi.org/10.1111/j.1469-7610.2006.01673.x |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=793 |
|  |
Reward-related decision-making in pediatric major depressive disorder: an fMRI study in Journal of Child Psychology and Psychiatry, 47-10 (October 2006)
