Developmental abnormalities in infants and children with acquired immune deficiency syndrome (AIDS) and AIDS-related complex / Monica H. ULTMANN in Developmental Medicine & Child Neurology, 27-5 (October 1985)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 27-5 (October 1985) . - p.563-571 Titre : Developmental abnormalities in infants and children with acquired immune deficiency syndrome (AIDS) and AIDS-related complex Type de document : texte imprimé Auteurs : Monica H. ULTMANN, Auteur ; Holly RUFF, Auteur ; Anita L. BELMAN, Auteur ; Brian E. NOVICK, Auteur ; Barbara CONE-WESSON, Auteur ; Herbert J. COHEN, Auteur ; Arye RUBINSTEIN, Auteur Année de publication : 1985 Article en page(s) : p.563-571 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Children with acquired immune deficiency syndrome (AIDS) display two types of clinical picture: a full-blown AIDS characterized by the presence of opportunistic infections and/or Kaposi's sarcoma and a prodromal stage now identified as AIDS-related complex (ARC). Neurological complications have been identified in infants and children with the disease. This paper discusses the developmental abnormalities in 16 pediatric patients, seven with AIDS and nine with ARC, ranging in age from six months to six years. In all cases, the mothers of these children either had ARC, AIDS and/or used intravenous drugs. Developmental histories showed delayed acquisition of milestones in most children following the diagnosis of AIDS or ARC, with delayed motor milestones consistently noted in both groups. Several children with AIDS actually lost milestones as their illness progressed; this has not occurred in the ARC group. Psychometric testing revealed more severe cognitive dysfunction in the group with AIDS. Involvement of the central nervous system was documented clinically, radiologically, and/or electrophysiologically in all patients with AIDS. In the ARC group the course of the illness has shown greater variability. Medical and social factors that may contribute to the developmental abnormalities are discussed. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=595 [article] Developmental abnormalities in infants and children with acquired immune deficiency syndrome (AIDS) and AIDS-related complex [texte imprimé] / Monica H. ULTMANN, Auteur ; Holly RUFF, Auteur ; Anita L. BELMAN, Auteur ; Brian E. NOVICK, Auteur ; Barbara CONE-WESSON, Auteur ; Herbert J. COHEN, Auteur ; Arye RUBINSTEIN, Auteur . - 1985 . - p.563-571. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 27-5 (October 1985) . - p.563-571 Index. décimale : PER Périodiques Résumé : Children with acquired immune deficiency syndrome (AIDS) display two types of clinical picture: a full-blown AIDS characterized by the presence of opportunistic infections and/or Kaposi's sarcoma and a prodromal stage now identified as AIDS-related complex (ARC). Neurological complications have been identified in infants and children with the disease. This paper discusses the developmental abnormalities in 16 pediatric patients, seven with AIDS and nine with ARC, ranging in age from six months to six years. In all cases, the mothers of these children either had ARC, AIDS and/or used intravenous drugs. Developmental histories showed delayed acquisition of milestones in most children following the diagnosis of AIDS or ARC, with delayed motor milestones consistently noted in both groups. Several children with AIDS actually lost milestones as their illness progressed; this has not occurred in the ARC group. Psychometric testing revealed more severe cognitive dysfunction in the group with AIDS. Involvement of the central nervous system was documented clinically, radiologically, and/or electrophysiologically in all patients with AIDS. In the ARC group the course of the illness has shown greater variability. Medical and social factors that may contribute to the developmental abnormalities are discussed. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=595

Periventricular low density as a predictor of neurobehavioral outcome in very low-birthweight infants / Cecelia MCCARTON-DAUM in Developmental Medicine & Child Neurology, 25-5 (October 1983)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 25-5 (October 1983) . - p.559-565 Titre : Periventricular low density as a predictor of neurobehavioral outcome in very low-birthweight infants Type de document : texte imprimé Auteurs : Cecelia MCCARTON-DAUM, Auteur ; Herbert G. VAUGHAN, Auteur ; Allan DANZIGER, Auteur ; Holly RUFF, Auteur Année de publication : 1983 Article en page(s) : p.559-565 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Sixty-four low-birthweight infants (less than 1500 g) were studied prospectively by cranial computerized tomography (CT) and by periodic neurobehavioral assessments. CT scans were obtained at 40 weeks postconceptional age. Neurobehavioral development was assessed by the Bayley Scales of Infant Development at seven, 12 and 18 months corrected age. 47 infants (73 per cent) had areas of diffuse periventricular low densities (PVLD). As a group, infants with PVLD had deviant Bayley scores for both mental and motor development at all follow-up ages. Scores for these infants were significantly lower than scores for infants with normal CT scans or scans with only focal low densities. It is concluded that very-low birthweight infants have an unexpectedly high prevalence of diffuse PVLD, and that this CT finding at 40 weeks postconceptional age is associated with abnormal neurobehavioral development throughout the first 18 months of life. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568 [article] Periventricular low density as a predictor of neurobehavioral outcome in very low-birthweight infants [texte imprimé] / Cecelia MCCARTON-DAUM, Auteur ; Herbert G. VAUGHAN, Auteur ; Allan DANZIGER, Auteur ; Holly RUFF, Auteur . - 1983 . - p.559-565. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 25-5 (October 1983) . - p.559-565 Index. décimale : PER Périodiques Résumé : Sixty-four low-birthweight infants (less than 1500 g) were studied prospectively by cranial computerized tomography (CT) and by periodic neurobehavioral assessments. CT scans were obtained at 40 weeks postconceptional age. Neurobehavioral development was assessed by the Bayley Scales of Infant Development at seven, 12 and 18 months corrected age. 47 infants (73 per cent) had areas of diffuse periventricular low densities (PVLD). As a group, infants with PVLD had deviant Bayley scores for both mental and motor development at all follow-up ages. Scores for these infants were significantly lower than scores for infants with normal CT scans or scans with only focal low densities. It is concluded that very-low birthweight infants have an unexpectedly high prevalence of diffuse PVLD, and that this CT finding at 40 weeks postconceptional age is associated with abnormal neurobehavioral development throughout the first 18 months of life. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=568

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