Determinants of Leaky Gut and Gut Microbiota Differences in Children With Autism Spectrum Disorder and Their Siblings / Gülsüm YITIK TONKAZ in Journal of Autism and Developmental Disorders, 53-7 (July 2023)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 53-7 (July 2023) . - p.2703-2716 Titre : Determinants of Leaky Gut and Gut Microbiota Differences in Children With Autism Spectrum Disorder and Their Siblings Type de document : Texte imprimé et/ou numérique Auteurs : Gülsüm YITIK TONKAZ, Auteur ; Ibrahim Selçuk ESIN, Auteur ; Bahadir TURAN, Auteur ; Hakan USLU, Auteur ; Onur Burak DURSUN, Auteur Article en page(s) : p.2703-2716 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Leaky gut hypothesis is one of the well-known theory which tries to explain etiology of Autism Spectrum Disorder (ASD). Unfortunately there is still a gap of evidence to investigate the corner points of the hypothesis. The aim of this study was to investigate the determinants of leaky gut in children with ASD, their siblings and healthy controls. Intestinal microbiota was found to be similar between ASD and sibling groups. Biological markers of bacterial translocation showed a significant difference in the sibling group, whereas the marker indicating local inflammation was not different between the groups. The findings from this study did not support the role of Gut microbiota or leaky gut on the etiology of autism. En ligne : https://doi.org/10.1007/s10803-022-05540-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508 [article] Determinants of Leaky Gut and Gut Microbiota Differences in Children With Autism Spectrum Disorder and Their Siblings [Texte imprimé et/ou numérique] / Gülsüm YITIK TONKAZ, Auteur ; Ibrahim Selçuk ESIN, Auteur ; Bahadir TURAN, Auteur ; Hakan USLU, Auteur ; Onur Burak DURSUN, Auteur . - p.2703-2716. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 53-7 (July 2023) . - p.2703-2716 Index. décimale : PER Périodiques Résumé : Leaky gut hypothesis is one of the well-known theory which tries to explain etiology of Autism Spectrum Disorder (ASD). Unfortunately there is still a gap of evidence to investigate the corner points of the hypothesis. The aim of this study was to investigate the determinants of leaky gut in children with ASD, their siblings and healthy controls. Intestinal microbiota was found to be similar between ASD and sibling groups. Biological markers of bacterial translocation showed a significant difference in the sibling group, whereas the marker indicating local inflammation was not different between the groups. The findings from this study did not support the role of Gut microbiota or leaky gut on the etiology of autism. En ligne : https://doi.org/10.1007/s10803-022-05540-z Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=508

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