Development in infants with autism spectrum disorders: a prospective study / Rebecca LANDA in Journal of Child Psychology and Psychiatry, 47-6 (June 2006)  

Public ISBD [article]  inJournal of Child Psychology and Psychiatry > 47-6 (June 2006) . - p.629–638 Titre : Development in infants with autism spectrum disorders: a prospective study Type de document : Texte imprimé et/ou numérique Auteurs : Rebecca LANDA, Auteur ; Elizabeth GARRETT-MAYER, Auteur Année de publication : 2006 Article en page(s) : p.629–638 Langues : Anglais (eng) Mots-clés : Autism autism-spectrum-disorder autistic-disorder language-impairment language-delay language-disorder motor-skills pervasive-developmental-disorder siblings Index. décimale : PER Périodiques Résumé : Background: Autism is rarely diagnosed before three years of age despite evidence suggesting prenatal abnormalities in neurobiological processes. Little is known about when or how development becomes disrupted in the first two years of life in autism. Such information is needed to facilitate early detection and early intervention. Methods: This prospective study of autism spectrum disorders (ASD) examined development using the Mullen Scales of Early Learning (MSEL) in 87 infants tested at target ages 6, 14, and 24 months. Participants came from infants at high risk (siblings of children with autism) and low risk (no family history of autism) groups. Based on language test scores, Autism Diagnostic Observation Schedule, and clinical judgment at 24 months of age, participants were categorized as: unaffected, ASD, or language delayed (LD). Longitudinal linear regression and ANOVA models were applied to MSEL raw scores, and estimates were compared between the three diagnostic groups. Results: No statistically significant group differences were detected at 6 months. By 14 months of age, the ASD group performed significantly worse than the unaffected group on all scales except Visual Reception. By 24 months of age, the ASD group performed significantly worse than the unaffected group in all domains, and worse than the language delayed group in Gross Motor, Fine Motor, and Receptive Language. The developmental trajectory of the ASD group was slower than the other groups', and showed a significant decrease in development between the first and second birthdays. Conclusions: Variations from typical and language delayed development are detectable in many children with ASD using a measure of general development by 24 months of age. Unusual slowing in performance occurred between 14 and 24 months of age in ASD. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01531.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=748 [article] Development in infants with autism spectrum disorders: a prospective study [Texte imprimé et/ou numérique] / Rebecca LANDA, Auteur ; Elizabeth GARRETT-MAYER, Auteur . - 2006 . - p.629–638. Langues : Anglais (eng) in Journal of Child Psychology and Psychiatry > 47-6 (June 2006) . - p.629–638 Mots-clés : Autism autism-spectrum-disorder autistic-disorder language-impairment language-delay language-disorder motor-skills pervasive-developmental-disorder siblings Index. décimale : PER Périodiques Résumé : Background: Autism is rarely diagnosed before three years of age despite evidence suggesting prenatal abnormalities in neurobiological processes. Little is known about when or how development becomes disrupted in the first two years of life in autism. Such information is needed to facilitate early detection and early intervention. Methods: This prospective study of autism spectrum disorders (ASD) examined development using the Mullen Scales of Early Learning (MSEL) in 87 infants tested at target ages 6, 14, and 24 months. Participants came from infants at high risk (siblings of children with autism) and low risk (no family history of autism) groups. Based on language test scores, Autism Diagnostic Observation Schedule, and clinical judgment at 24 months of age, participants were categorized as: unaffected, ASD, or language delayed (LD). Longitudinal linear regression and ANOVA models were applied to MSEL raw scores, and estimates were compared between the three diagnostic groups. Results: No statistically significant group differences were detected at 6 months. By 14 months of age, the ASD group performed significantly worse than the unaffected group on all scales except Visual Reception. By 24 months of age, the ASD group performed significantly worse than the unaffected group in all domains, and worse than the language delayed group in Gross Motor, Fine Motor, and Receptive Language. The developmental trajectory of the ASD group was slower than the other groups', and showed a significant decrease in development between the first and second birthdays. Conclusions: Variations from typical and language delayed development are detectable in many children with ASD using a measure of general development by 24 months of age. Unusual slowing in performance occurred between 14 and 24 months of age in ASD. En ligne : http://dx.doi.org/10.1111/j.1469-7610.2006.01531.x Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=748

Rates and Predictors of Adherence to Psychotropic Medications in Children with Autism Spectrum Disorders / Sarah L. LOGAN in Journal of Autism and Developmental Disorders, 44-11 (November 2014)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2931-2948 Titre : Rates and Predictors of Adherence to Psychotropic Medications in Children with Autism Spectrum Disorders Type de document : Texte imprimé et/ou numérique Auteurs : Sarah L. LOGAN, Auteur ; Laura A. CARPENTER, Auteur ; R. Scott LESLIE, Auteur ; Kelly S. HUNT, Auteur ; Elizabeth GARRETT-MAYER, Auteur ; Jane CHARLES, Auteur ; Joyce S. NICHOLAS, Auteur Article en page(s) : p.2931-2948 Langues : Anglais (eng) Mots-clés : Psychotropics  Treatment adherence  Public health surveillance  Autism Index. décimale : PER Périodiques Résumé : Medication adherence in children is poor, particularly among those with chronic or mental health disorders. However, adherence has not been fully assessed in autism spectrum disorders (ASDs). The validated proportion of days covered method was used to quantify adherence to psychotropic medication in Medicaid-eligible children who met diagnostic criteria for ASD between 2000 and 2008 (N = 628). Among children prescribed attention deficit hyperactivity disorder (ADHD) medications, antidepressants, or antipsychotics, 44, 40 and 52 % were adherent respectively. Aggressive behaviors and abnormalities in eating, drinking, and/or sleeping, co-occurring ADHD, and the Medication Regimen Complexity Index were the most significant predictors of adherence rather than demographics or core deficits of ASD. Identifying barriers to adherence in ASD may ultimately lead to improved treatment outcomes. En ligne : http://dx.doi.org/10.1007/s10803-014-2156-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241 [article] Rates and Predictors of Adherence to Psychotropic Medications in Children with Autism Spectrum Disorders [Texte imprimé et/ou numérique] / Sarah L. LOGAN, Auteur ; Laura A. CARPENTER, Auteur ; R. Scott LESLIE, Auteur ; Kelly S. HUNT, Auteur ; Elizabeth GARRETT-MAYER, Auteur ; Jane CHARLES, Auteur ; Joyce S. NICHOLAS, Auteur . - p.2931-2948. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 44-11 (November 2014) . - p.2931-2948 Mots-clés : Psychotropics  Treatment adherence  Public health surveillance  Autism Index. décimale : PER Périodiques Résumé : Medication adherence in children is poor, particularly among those with chronic or mental health disorders. However, adherence has not been fully assessed in autism spectrum disorders (ASDs). The validated proportion of days covered method was used to quantify adherence to psychotropic medication in Medicaid-eligible children who met diagnostic criteria for ASD between 2000 and 2008 (N = 628). Among children prescribed attention deficit hyperactivity disorder (ADHD) medications, antidepressants, or antipsychotics, 44, 40 and 52 % were adherent respectively. Aggressive behaviors and abnormalities in eating, drinking, and/or sleeping, co-occurring ADHD, and the Medication Regimen Complexity Index were the most significant predictors of adherence rather than demographics or core deficits of ASD. Identifying barriers to adherence in ASD may ultimately lead to improved treatment outcomes. En ligne : http://dx.doi.org/10.1007/s10803-014-2156-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=241

Response to Joint Attention in Toddlers at Risk for Autism Spectrum Disorder: A Prospective Study / Michelle SULLIVAN in Journal of Autism and Developmental Disorders, 37-1 (January 2007)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 37-1 (January 2007) . - p.37-48 Titre : Response to Joint Attention in Toddlers at Risk for Autism Spectrum Disorder: A Prospective Study Type de document : Texte imprimé et/ou numérique Auteurs : Michelle SULLIVAN, Auteur ; Rebecca LANDA, Auteur ; Julianna FINELLI, Auteur ; Alison MARVIN, Auteur ; Elizabeth GARRETT-MAYER, Auteur ; Margaret L. BAUMAN, Auteur Année de publication : 2007 Article en page(s) : p.37-48 Langues : Anglais (eng) Mots-clés : Autism Joint-attention Longitudinal Phenotype Siblings Social-Communication Index. décimale : PER Périodiques Résumé : Response to joint attention (RJA) is impaired in preschoolers with autism spectrum disorder (ASD) and is pivotal to social and communication development. Response to joint attention was examined at 14 and 24 months in 51 children at high risk for autism (siblings of children with autism). Outcome groups at age 3 years included ASD (n = 16), broader autism phenotype (n = 8), and non-broader autism phenotype (n = 27). The ASD group made minimal improvement in RJA between 14 and 24 months, but stability of RJA across tasks increased for all three groups. Significantly, lower RJA was observed for the ASD group at 24 months. Response to joint attention performance at 14 months predicted ASD outcome. Response to joint attention is an important screening and early intervention target. En ligne : http://dx.doi.org/10.1007/s10803-006-0335-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=612 [article] Response to Joint Attention in Toddlers at Risk for Autism Spectrum Disorder: A Prospective Study [Texte imprimé et/ou numérique] / Michelle SULLIVAN, Auteur ; Rebecca LANDA, Auteur ; Julianna FINELLI, Auteur ; Alison MARVIN, Auteur ; Elizabeth GARRETT-MAYER, Auteur ; Margaret L. BAUMAN, Auteur . - 2007 . - p.37-48. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 37-1 (January 2007) . - p.37-48 Mots-clés : Autism Joint-attention Longitudinal Phenotype Siblings Social-Communication Index. décimale : PER Périodiques Résumé : Response to joint attention (RJA) is impaired in preschoolers with autism spectrum disorder (ASD) and is pivotal to social and communication development. Response to joint attention was examined at 14 and 24 months in 51 children at high risk for autism (siblings of children with autism). Outcome groups at age 3 years included ASD (n = 16), broader autism phenotype (n = 8), and non-broader autism phenotype (n = 27). The ASD group made minimal improvement in RJA between 14 and 24 months, but stability of RJA across tasks increased for all three groups. Significantly, lower RJA was observed for the ASD group at 24 months. Response to joint attention performance at 14 months predicted ASD outcome. Response to joint attention is an important screening and early intervention target. En ligne : http://dx.doi.org/10.1007/s10803-006-0335-3 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=612

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