Effects of rationalizing drug treatment of patients with epilepsy and mental retardation / Ettore BEGHI in Developmental Medicine & Child Neurology, 29-3 (June 1987)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 29-3 (June 1987) . - p.363-369 Titre : Effects of rationalizing drug treatment of patients with epilepsy and mental retardation Type de document : Texte imprimé et/ou numérique Auteurs : Ettore BEGHI, Auteur ; Paola BOLLINI, Auteur ; Rocco DI MASCIO, Auteur ; Nicolo CERISOLA, Auteur ; Tiziana MERLONI, Auteur ; Ernesto MANGHI, Auteur Année de publication : 1987 Article en page(s) : p.363-369 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Eighty patients with epilepsy and mental retardation were observed for a mean period of 12.5 months to assess the effects of 'rationalisation' of their drug treatment on both epilepsy and behaviour. Anticonvulsant drugs were modified to provide the best seizure control with the lowest toxicity, and psychotropic drugs also were monitored and modified if necessary to obtain the best results. At the end of the follow-up period the number of anti-epileptic drugs had fallen from 1.84 to 1.05 per patient. On admission to the study 47 patients were being treated with 85 psychotropic drugs: at the end of the follow-up 44 patients were taking 63 drugs. Seizures were significantly reduced in 16 of 39 patients with unsatisfactory control on admission to the study. Among 41 patients with initial satisfactory control, only 16 had relapse of seizures. Behavior did not change significantly. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=625 [article] Effects of rationalizing drug treatment of patients with epilepsy and mental retardation [Texte imprimé et/ou numérique] / Ettore BEGHI, Auteur ; Paola BOLLINI, Auteur ; Rocco DI MASCIO, Auteur ; Nicolo CERISOLA, Auteur ; Tiziana MERLONI, Auteur ; Ernesto MANGHI, Auteur . - 1987 . - p.363-369. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 29-3 (June 1987) . - p.363-369 Index. décimale : PER Périodiques Résumé : Eighty patients with epilepsy and mental retardation were observed for a mean period of 12.5 months to assess the effects of 'rationalisation' of their drug treatment on both epilepsy and behaviour. Anticonvulsant drugs were modified to provide the best seizure control with the lowest toxicity, and psychotropic drugs also were monitored and modified if necessary to obtain the best results. At the end of the follow-up period the number of anti-epileptic drugs had fallen from 1.84 to 1.05 per patient. On admission to the study 47 patients were being treated with 85 psychotropic drugs: at the end of the follow-up 44 patients were taking 63 drugs. Seizures were significantly reduced in 16 of 39 patients with unsatisfactory control on admission to the study. Among 41 patients with initial satisfactory control, only 16 had relapse of seizures. Behavior did not change significantly. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=625

Infantile febrile status epilepticus: risk factors and outcome / Francesco VIANI in Developmental Medicine & Child Neurology, 29-4 (August 1987)

Public ISBD [article]  inDevelopmental Medicine & Child Neurology > 29-4 (August 1987) . - p.495-501 Titre : Infantile febrile status epilepticus: risk factors and outcome Type de document : Texte imprimé et/ou numérique Auteurs : Francesco VIANI, Auteur ; Ettore BEGHI, Auteur ; A. ROMEO, Auteur ; A. VAN LIERDE, Auteur Année de publication : 1987 Article en page(s) : p.495-501 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The medical records of 68 children who had had infantile febrile status epilepticus (FSE) were examined. Follow-up periods ranged from three to 28 years (mean 8 years 10 months). Details were abstracted of relevant medical events prior to FSE, diagnosis of the febrile illness, age at onset and main characteristics of FSE, and outcome (subsequent febrile convulsions and/or epilepsy, neurological and psychiatric disorders). Neither medical events prior to FSE nor aetiology of fever were associated with subsequent febrile convulsions, epilepsy, or neurological or psychiatric abnormalities. There was a significant association between age at onset of FSE and both subsequent epilepsy and CNS disorders. 12 of the 13 children who had had transient or persistent post-ictal hemiparesis subsequently developed epilepsy. Of the 46 children who later developed epilepsy, 34 had partial seizures and 12 had generalized seizures. The latter were more common among children who had had FSE before the age of one year. Likewise, all those who developed severe myoclonic epilepsy in infancy had their first FSE before age one. These findings suggest that age at onset of FSE is the most important feature determining long-term outcome. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=627 [article] Infantile febrile status epilepticus: risk factors and outcome [Texte imprimé et/ou numérique] / Francesco VIANI, Auteur ; Ettore BEGHI, Auteur ; A. ROMEO, Auteur ; A. VAN LIERDE, Auteur . - 1987 . - p.495-501. Langues : Anglais (eng) in Developmental Medicine & Child Neurology > 29-4 (August 1987) . - p.495-501 Index. décimale : PER Périodiques Résumé : The medical records of 68 children who had had infantile febrile status epilepticus (FSE) were examined. Follow-up periods ranged from three to 28 years (mean 8 years 10 months). Details were abstracted of relevant medical events prior to FSE, diagnosis of the febrile illness, age at onset and main characteristics of FSE, and outcome (subsequent febrile convulsions and/or epilepsy, neurological and psychiatric disorders). Neither medical events prior to FSE nor aetiology of fever were associated with subsequent febrile convulsions, epilepsy, or neurological or psychiatric abnormalities. There was a significant association between age at onset of FSE and both subsequent epilepsy and CNS disorders. 12 of the 13 children who had had transient or persistent post-ictal hemiparesis subsequently developed epilepsy. Of the 46 children who later developed epilepsy, 34 had partial seizures and 12 had generalized seizures. The latter were more common among children who had had FSE before the age of one year. Likewise, all those who developed severe myoclonic epilepsy in infancy had their first FSE before age one. These findings suggest that age at onset of FSE is the most important feature determining long-term outcome. Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=627

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