Atypical Resting-State EEG Graph Metrics of Network Efficiency Across Development in Autism and Their Association with Social Cognition: Results from the LEAP Study / E. DE JONGE in Journal of Autism and Developmental Disorders, 56-7 (July 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-7 (July 2026) . - p.2557-2573 Titre : Atypical Resting-State EEG Graph Metrics of Network Efficiency Across Development in Autism and Their Association with Social Cognition: Results from the LEAP Study Type de document : texte imprimé Auteurs : E. DE JONGE, Auteur ; P. GARCÉS, Auteur ; A. DE BILDT, Auteur ; Y. GROEN, Auteur ; E.J.H. JONES, Auteur ; L. MASON, Auteur ; R. J. HOLT, Auteur ; H. HAYWARD, Auteur ; D. MURPHY, Auteur ; B. OAKLEY, Auteur ; T. CHARMAN, Auteur ; J. AHMAD, Auteur ; S. BARON-COHEN, Auteur ; M.H. JOHNSON, Auteur ; T. BANASCHEWSKI, Auteur ; S. DURSTON, Auteur ; B. ORANJE, Auteur ; S. BÖLTE, Auteur ; J. BUITELAAR, Auteur ; P. J. HOEKSTRA, Auteur ; A. DIETRICH, Auteur ; E. U. Aims Leap group THE, Auteur Article en page(s) : p.2557-2573 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Autism has been associated with differences in functional brain network organization. However, the exact nature of these differences across development compared to non-autistic individuals and their relationship to autism-related social cognition, remains unclear. This study first aimed to identify EEG resting-state network characteristics in autistic versus non-autistic children, adolescents, and adults. Second, we investigated associations with social cognition measures. Analyzing resting-state EEG data from the EU-AIMS Longitudinal European Autism Project, we compared network metrics (global efficiency, clustering coefficient, and small-worldness) between 344 autistic and non-autistic individuals within and across age groups in four frequency bands (delta, theta, alpha, and beta). If significant, we explored their relationships to measures of empathy (empathy quotient), complex emotion recognition [reading the mind in the eyes task (RMET)], and theory of mind (animated shapes task). Compared to their non-autistic peers, autistic adolescents showed lower alpha global efficiency, while autistic adults showed lower alpha clustering and small-worldness. No network differences were observed among children. In adolescents, higher long-range integration was tentatively associated with higher RMET scores; in those with high autistic traits, higher long-range integration related to fewer parent-reported empathic behaviors. No brain-behavior relationships were observed in adults. Our findings suggest subtle differences in network topology between autistic and non-autistic individuals, with less efficient long-range efficiency during adolescence, and less local and overall network efficiency in adulthood. Furthermore, long-range integration may play a role in complex emotion recognition and empathy difficulties associated with autism in adolescence. En ligne : https://doi.org/10.1007/s10803-025-06731-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=590 [article] Atypical Resting-State EEG Graph Metrics of Network Efficiency Across Development in Autism and Their Association with Social Cognition: Results from the LEAP Study [texte imprimé] / E. DE JONGE, Auteur ; P. GARCÉS, Auteur ; A. DE BILDT, Auteur ; Y. GROEN, Auteur ; E.J.H. JONES, Auteur ; L. MASON, Auteur ; R. J. HOLT, Auteur ; H. HAYWARD, Auteur ; D. MURPHY, Auteur ; B. OAKLEY, Auteur ; T. CHARMAN, Auteur ; J. AHMAD, Auteur ; S. BARON-COHEN, Auteur ; M.H. JOHNSON, Auteur ; T. BANASCHEWSKI, Auteur ; S. DURSTON, Auteur ; B. ORANJE, Auteur ; S. BÖLTE, Auteur ; J. BUITELAAR, Auteur ; P. J. HOEKSTRA, Auteur ; A. DIETRICH, Auteur ; E. U. Aims Leap group THE, Auteur . - p.2557-2573. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-7 (July 2026) . - p.2557-2573 Index. décimale : PER Périodiques Résumé : Autism has been associated with differences in functional brain network organization. However, the exact nature of these differences across development compared to non-autistic individuals and their relationship to autism-related social cognition, remains unclear. This study first aimed to identify EEG resting-state network characteristics in autistic versus non-autistic children, adolescents, and adults. Second, we investigated associations with social cognition measures. Analyzing resting-state EEG data from the EU-AIMS Longitudinal European Autism Project, we compared network metrics (global efficiency, clustering coefficient, and small-worldness) between 344 autistic and non-autistic individuals within and across age groups in four frequency bands (delta, theta, alpha, and beta). If significant, we explored their relationships to measures of empathy (empathy quotient), complex emotion recognition [reading the mind in the eyes task (RMET)], and theory of mind (animated shapes task). Compared to their non-autistic peers, autistic adolescents showed lower alpha global efficiency, while autistic adults showed lower alpha clustering and small-worldness. No network differences were observed among children. In adolescents, higher long-range integration was tentatively associated with higher RMET scores; in those with high autistic traits, higher long-range integration related to fewer parent-reported empathic behaviors. No brain-behavior relationships were observed in adults. Our findings suggest subtle differences in network topology between autistic and non-autistic individuals, with less efficient long-range efficiency during adolescence, and less local and overall network efficiency in adulthood. Furthermore, long-range integration may play a role in complex emotion recognition and empathy difficulties associated with autism in adolescence. En ligne : https://doi.org/10.1007/s10803-025-06731-0 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=590

A Concurrent Validity Study of the Mullen Scales of Early Learning (MSEL) and the MacArthur-Bates Communicative Developmental Inventory (CDI) in Infants with an Elevated Likelihood or Diagnosis of Autism / Z. BELTEKI in Journal of Autism and Developmental Disorders, 56-6 (June 2026)  

Public ISBD [article]  inJournal of Autism and Developmental Disorders > 56-6 (June 2026) . - p.2323-2338 Titre : A Concurrent Validity Study of the Mullen Scales of Early Learning (MSEL) and the MacArthur-Bates Communicative Developmental Inventory (CDI) in Infants with an Elevated Likelihood or Diagnosis of Autism Type de document : texte imprimé Auteurs : Z. BELTEKI, Auteur ; E. K. WARD, Auteur ; J. BEGUM-ALI, Auteur ; C. VAN DEN BOOMEN, Auteur ; S. BÖLTE, Auteur ; J. BUITELAAR, Auteur ; T. CHARMAN, Auteur ; E. DEMURIE, Auteur ; T. FALCK-YTTER, Auteur ; S. HUNNIUS, Auteur ; M.H. JOHNSON, Auteur ; E. J.H. JONES, Auteur ; I. OOSTERLING, Auteur ; G. PASCO, Auteur ; M. K. J. PIJL, Auteur ; A. RADKOWSKA, Auteur ; M. RUDLING, Auteur ; P. TOMALSKI, Auteur ; P. WARREYN, Auteur ; C. JUNGE, Auteur ; E. HAMAN, Auteur Article en page(s) : p.2323-2338 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Infants at elevated likelihood for or later diagnosed with autism typically have smaller vocabularies than their peers, as shown by the Mullen Scales of Early Learning (MSEL) and the MacArthur-Bates Communicative Developmental Inventory (CDI). However, the extent to which MSEL and CDI scores align remains unclear, especially across clinical and non-clinical populations. This study examined whether the concurrent validity of the MSEL and CDI differs based on autism likelihood and diagnosis. Data from 720 14-month-old infants were analysed, grouped by likelihood (elevated vs. typical) and diagnosis at 36 months (diagnosed vs. not diagnosed). Vocabulary scores were compared across both likelihood and diagnostic groups. Moderate correlations were observed between the MSEL and CDI in most groups (rs range = [.34–.58]). One exception was that the expressive scores of elevated likelihood infants on the MSEL and CDI were more closely associated than the expressive scores of typical likelihood infants. Diagnosed infants had lower vocabulary scores than non-diagnosed peers on both the MSEL and CDI. The elevated likelihood group showed lower scores on the MSEL but not the CDI compared to typical likelihood infants. The moderate correlations suggest that the MSEL and CDI assess different aspects of language in infancy. These associations were weaker than previously reported in autistic children. Differences in vocabulary scores across likelihood and diagnostic groups highlight the need for further research to understand the association between these measures. En ligne : https://doi.org/10.1007/s10803-024-06652-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=588 [article] A Concurrent Validity Study of the Mullen Scales of Early Learning (MSEL) and the MacArthur-Bates Communicative Developmental Inventory (CDI) in Infants with an Elevated Likelihood or Diagnosis of Autism [texte imprimé] / Z. BELTEKI, Auteur ; E. K. WARD, Auteur ; J. BEGUM-ALI, Auteur ; C. VAN DEN BOOMEN, Auteur ; S. BÖLTE, Auteur ; J. BUITELAAR, Auteur ; T. CHARMAN, Auteur ; E. DEMURIE, Auteur ; T. FALCK-YTTER, Auteur ; S. HUNNIUS, Auteur ; M.H. JOHNSON, Auteur ; E. J.H. JONES, Auteur ; I. OOSTERLING, Auteur ; G. PASCO, Auteur ; M. K. J. PIJL, Auteur ; A. RADKOWSKA, Auteur ; M. RUDLING, Auteur ; P. TOMALSKI, Auteur ; P. WARREYN, Auteur ; C. JUNGE, Auteur ; E. HAMAN, Auteur . - p.2323-2338. Langues : Anglais (eng) in Journal of Autism and Developmental Disorders > 56-6 (June 2026) . - p.2323-2338 Index. décimale : PER Périodiques Résumé : Infants at elevated likelihood for or later diagnosed with autism typically have smaller vocabularies than their peers, as shown by the Mullen Scales of Early Learning (MSEL) and the MacArthur-Bates Communicative Developmental Inventory (CDI). However, the extent to which MSEL and CDI scores align remains unclear, especially across clinical and non-clinical populations. This study examined whether the concurrent validity of the MSEL and CDI differs based on autism likelihood and diagnosis. Data from 720 14-month-old infants were analysed, grouped by likelihood (elevated vs. typical) and diagnosis at 36 months (diagnosed vs. not diagnosed). Vocabulary scores were compared across both likelihood and diagnostic groups. Moderate correlations were observed between the MSEL and CDI in most groups (rs range = [.34–.58]). One exception was that the expressive scores of elevated likelihood infants on the MSEL and CDI were more closely associated than the expressive scores of typical likelihood infants. Diagnosed infants had lower vocabulary scores than non-diagnosed peers on both the MSEL and CDI. The elevated likelihood group showed lower scores on the MSEL but not the CDI compared to typical likelihood infants. The moderate correlations suggest that the MSEL and CDI assess different aspects of language in infancy. These associations were weaker than previously reported in autistic children. Differences in vocabulary scores across likelihood and diagnostic groups highlight the need for further research to understand the association between these measures. En ligne : https://doi.org/10.1007/s10803-024-06652-4 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=588

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