[article]
| Titre : |
Development and Validation of a Short Version Eye-Tracking Paradigm for the Screening and Diagnosis of Autism Spectrum Disorder in Qatar |
| Type de document : |
texte imprimé |
| Auteurs : |
Fouad Al SHABAN, Auteur ; Iman GHAZAL, Auteur ; Fatema AL-FARAJ, Auteur ; Sarah AQEL, Auteur ; I. Richard THOMPSON, Auteur |
| Article en page(s) : |
p.e70242 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
autism spectrum disorder diagnosis eye-tracking gaze behavior rapid screening |
| Index. décimale : |
PER Périodiques |
| Résumé : |
ABSTRACT Objective behavioral assessments for autism spectrum disorder (ASD) are often time-intensive and require substantial clinical expertise. Eye-tracking?based paradigms offer quantifiable measures of social attention that can complement traditional tools. The current study builds on our previously validated Arabic-language Autism Index (AI) by developing and validating a 4?min short version designed to improve feasibility in clinical and community settings while maintaining diagnostic accuracy. A total of 236 participants (127 with ASD, 109 non-autistic controls including those with developmental delays (DD)) aged 1?16?years were assessed using an eye-tracking paradigm consisting of 19 short dynamic videos depicting social and non-social scenes. The AI was computed as the ratio of dwell time toward social versus non-social stimuli. Diagnostic classification was established using ADOS-2 and SCQ. Reliability and validity were assessed using Cronbach's α, Pearson's r, and ROC analyses, including age-stratified performance and comparison with the original 10?min version. Feasibility was assessed by the proportion of valid stimuli. The short-version AI demonstrated excellent internal consistency (α?=?0.91) and test?retest reliability (r?=?0.83). Diagnostic accuracy was high (AUC?=?0.878, SE?=?0.023), with age-stratified AUCs ranging from 0.846 to 0.939. AI scores correlated strongly with ADOS-2 severity (r?=?0.54, p?0.001) and SCQ total scores (r?=?0.43, p?0.001). Compared with the 10?min original version (AUC?=?0.73), the short paradigm achieved higher accuracy and feasibility (valid stimuli: 89% vs. 80%). The current eye-tracking paradigm demonstrates promising diagnostic performance while substantially reducing assessment time and cognitive demand. The findings provide initial evidence supporting its potential as a scalable and cross-cultural tool for ASD screening and diagnosis, with further validation in independent and clinical cohorts supporting its translation into routine clinical practice. |
| En ligne : |
https://doi.org/10.1002/aur.70242 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=589 |
in Autism Research > 19-6 (June 2026) . - p.e70242
[article] Development and Validation of a Short Version Eye-Tracking Paradigm for the Screening and Diagnosis of Autism Spectrum Disorder in Qatar [texte imprimé] / Fouad Al SHABAN, Auteur ; Iman GHAZAL, Auteur ; Fatema AL-FARAJ, Auteur ; Sarah AQEL, Auteur ; I. Richard THOMPSON, Auteur . - p.e70242. Langues : Anglais ( eng) in Autism Research > 19-6 (June 2026) . - p.e70242
| Mots-clés : |
autism spectrum disorder diagnosis eye-tracking gaze behavior rapid screening |
| Index. décimale : |
PER Périodiques |
| Résumé : |
ABSTRACT Objective behavioral assessments for autism spectrum disorder (ASD) are often time-intensive and require substantial clinical expertise. Eye-tracking?based paradigms offer quantifiable measures of social attention that can complement traditional tools. The current study builds on our previously validated Arabic-language Autism Index (AI) by developing and validating a 4?min short version designed to improve feasibility in clinical and community settings while maintaining diagnostic accuracy. A total of 236 participants (127 with ASD, 109 non-autistic controls including those with developmental delays (DD)) aged 1?16?years were assessed using an eye-tracking paradigm consisting of 19 short dynamic videos depicting social and non-social scenes. The AI was computed as the ratio of dwell time toward social versus non-social stimuli. Diagnostic classification was established using ADOS-2 and SCQ. Reliability and validity were assessed using Cronbach's α, Pearson's r, and ROC analyses, including age-stratified performance and comparison with the original 10?min version. Feasibility was assessed by the proportion of valid stimuli. The short-version AI demonstrated excellent internal consistency (α?=?0.91) and test?retest reliability (r?=?0.83). Diagnostic accuracy was high (AUC?=?0.878, SE?=?0.023), with age-stratified AUCs ranging from 0.846 to 0.939. AI scores correlated strongly with ADOS-2 severity (r?=?0.54, p?0.001) and SCQ total scores (r?=?0.43, p?0.001). Compared with the 10?min original version (AUC?=?0.73), the short paradigm achieved higher accuracy and feasibility (valid stimuli: 89% vs. 80%). The current eye-tracking paradigm demonstrates promising diagnostic performance while substantially reducing assessment time and cognitive demand. The findings provide initial evidence supporting its potential as a scalable and cross-cultural tool for ASD screening and diagnosis, with further validation in independent and clinical cohorts supporting its translation into routine clinical practice. |
| En ligne : |
https://doi.org/10.1002/aur.70242 |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=589 |
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