[article]
| Titre : |
Autism Spectrum Phenotype in Males and Females with Fragile X Full Mutation and Premutation |
| Type de document : |
Texte imprimé et/ou numérique |
| Auteurs : |
Sally M. CLIFFORD, Auteur ; Cheryl DISSANAYAKE, Auteur ; Quang M. BUI, Auteur ; Richard HUGGINS, Auteur ; Annette K. TAYLOR, Auteur ; Danuta Z. LOESCH, Auteur |
| Année de publication : |
2007 |
| Article en page(s) : |
p.738-747 |
| Langues : |
Anglais (eng) |
| Mots-clés : |
Fragile-X-syndrome-(FXS) Fragile-X-premutation-(FXP) Autism-Spectrum-Disorder-(ASD) Autism-Diagnostic-Observation-Schedule- Generic-(ADOS-G) Autism-Diagnostic-Interview-Revised-(ADI-R) |
| Index. décimale : |
PER Périodiques |
| Résumé : |
The behavioural phenotype of autism was assessed in individuals with full mutation and premutation fragile X syndrome (FXS) using the Autism Diagnostic Observation Scale-Generic (ADOS-G) and the Autism Diagnostic Interview (ADI-R). The participants, aged 5–80 years, comprised 33 males and 31 females with full mutation, 7 males and 43 females with premutation, and 38 non-fragile X relatives (29 males, 9 females). In the full mutation group, a total of 67% males and 23% females met either the Autism Disorder (AD) or the Autism Spectrum Disorder (ASD) criteria on at least one of the diagnostic tests. In the premutation group, 14% males and 5% females met the ADOS-G criteria for ASD. The presence of autism manifestations in males and females with full mutation and premutation provide support for a spectrum view. |
| En ligne : |
http://dx.doi.org/10.1007/s10803-006-0205-z |
| Permalink : |
https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=977 |
in Journal of Autism and Developmental Disorders > 37-4 (April 2007) . - p.738-747
|
Autism Spectrum Phenotype in Males and Females with Fragile X Full Mutation and Premutation in Journal of Autism and Developmental Disorders, 37-4 (April 2007)
