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Détail de l'auteur
Auteur Jonna B. WESTOVER |
Documents disponibles écrits par cet auteur (2)
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HLA Immune Function Genes in Autism / Anthony R. TORRES in Autism Research and Treatment, (November 2011)
[article]
Titre : HLA Immune Function Genes in Autism Type de document : Texte imprimé et/ou numérique Auteurs : Anthony R. TORRES, Auteur ; Jonna B. WESTOVER, Auteur ; Allen J. ROSENSPIRE, Auteur Année de publication : 2011 Article en page(s) : 13 p. Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : The human leukocyte antigen (HLA) genes on chromosome 6 are instrumental in many innate and adaptive immune responses. The HLA genes/haplotypes can also be involved in immune dysfunction and autoimmune diseases. It is now becoming apparent that many of the non-antigen-presenting HLA genes make significant contributions to autoimmune diseases. Interestingly, it has been reported that autism subjects often have associations with HLA genes/haplotypes, suggesting an underlying dysregulation of the immune system mediated by HLA genes. Genetic studies have only succeeded in identifying autism-causing genes in a small number of subjects suggesting that the genome has not been adequately interrogated. Close examination of the HLA region in autism has been relatively ignored, largely due to extraordinary genetic complexity. It is our proposition that genetic polymorphisms in the HLA region, especially in the non-antigen-presenting regions, may be important in the etiology of autism in certain subjects. En ligne : http://dx.doi.org/10.1155/2012/959073 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=153
in Autism Research and Treatment > (November 2011) . - 13 p.[article] HLA Immune Function Genes in Autism [Texte imprimé et/ou numérique] / Anthony R. TORRES, Auteur ; Jonna B. WESTOVER, Auteur ; Allen J. ROSENSPIRE, Auteur . - 2011 . - 13 p.
Langues : Anglais (eng)
in Autism Research and Treatment > (November 2011) . - 13 p.
Index. décimale : PER Périodiques Résumé : The human leukocyte antigen (HLA) genes on chromosome 6 are instrumental in many innate and adaptive immune responses. The HLA genes/haplotypes can also be involved in immune dysfunction and autoimmune diseases. It is now becoming apparent that many of the non-antigen-presenting HLA genes make significant contributions to autoimmune diseases. Interestingly, it has been reported that autism subjects often have associations with HLA genes/haplotypes, suggesting an underlying dysregulation of the immune system mediated by HLA genes. Genetic studies have only succeeded in identifying autism-causing genes in a small number of subjects suggesting that the genome has not been adequately interrogated. Close examination of the HLA region in autism has been relatively ignored, largely due to extraordinary genetic complexity. It is our proposition that genetic polymorphisms in the HLA region, especially in the non-antigen-presenting regions, may be important in the etiology of autism in certain subjects. En ligne : http://dx.doi.org/10.1155/2012/959073 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=153
Titre : Immune Dysfunction in Autism Spectrum Disorder Type de document : Texte imprimé et/ou numérique Auteurs : Jonna B. WESTOVER, Auteur ; Thayne L. SWEETEN, Auteur ; Michael BENSON, Auteur ; Patricia BRAY-WARD, Auteur ; Anthony R. TORRES, Auteur Année de publication : 2011 Importance : p.343-368 Langues : Anglais (eng) Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques En ligne : http://dx.doi.org/10.5772/22318 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=143 Immune Dysfunction in Autism Spectrum Disorder [Texte imprimé et/ou numérique] / Jonna B. WESTOVER, Auteur ; Thayne L. SWEETEN, Auteur ; Michael BENSON, Auteur ; Patricia BRAY-WARD, Auteur ; Anthony R. TORRES, Auteur . - 2011 . - p.343-368.
Langues : Anglais (eng)
Index. décimale : AUT-B AUT-B - L'Autisme - Ouvrages généraux et scientifiques En ligne : http://dx.doi.org/10.5772/22318 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=143 Exemplaires
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