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Détail de l'auteur
Auteur Len KATZ |
Documents disponibles écrits par cet auteur (1)
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Lexical decision as an endophenotype for reading comprehension: An exploration of an association / Adam J. NAPLES in Development and Psychopathology, 24-4 (November 2012)
[article]
Titre : Lexical decision as an endophenotype for reading comprehension: An exploration of an association Type de document : Texte imprimé et/ou numérique Auteurs : Adam J. NAPLES, Auteur ; Len KATZ, Auteur ; Elena L. GRIGORENKO, Auteur Année de publication : 2012 Article en page(s) : p.1345-1360 Langues : Anglais (eng) Index. décimale : PER Périodiques Résumé : Based on numerous suggestions in the literature, we evaluated lexical decision (LD) as a putative endophenotype for reading comprehension by investigating heritability estimates and segregation analyses parameter estimates for both of these phenotypes. Specifically, in a segregation analysis of a large sample of families, we established that there is little to no overlap between genes contributing to LD and reading comprehension and that the genetic mechanism behind LD derived from this analysis appears to be more complex than that for reading comprehension. We conclude that in our sample, LD is not a good candidate as an endophenotype for reading comprehension, despite previous suggestions from the literature. Based on this conclusion, we discuss the role and benefit of the endophenotype approach in studies of complex human cognitive functions. En ligne : http://dx.doi.org/10.1017/S0954579412000752 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182
in Development and Psychopathology > 24-4 (November 2012) . - p.1345-1360[article] Lexical decision as an endophenotype for reading comprehension: An exploration of an association [Texte imprimé et/ou numérique] / Adam J. NAPLES, Auteur ; Len KATZ, Auteur ; Elena L. GRIGORENKO, Auteur . - 2012 . - p.1345-1360.
Langues : Anglais (eng)
in Development and Psychopathology > 24-4 (November 2012) . - p.1345-1360
Index. décimale : PER Périodiques Résumé : Based on numerous suggestions in the literature, we evaluated lexical decision (LD) as a putative endophenotype for reading comprehension by investigating heritability estimates and segregation analyses parameter estimates for both of these phenotypes. Specifically, in a segregation analysis of a large sample of families, we established that there is little to no overlap between genes contributing to LD and reading comprehension and that the genetic mechanism behind LD derived from this analysis appears to be more complex than that for reading comprehension. We conclude that in our sample, LD is not a good candidate as an endophenotype for reading comprehension, despite previous suggestions from the literature. Based on this conclusion, we discuss the role and benefit of the endophenotype approach in studies of complex human cognitive functions. En ligne : http://dx.doi.org/10.1017/S0954579412000752 Permalink : https://www.cra-rhone-alpes.org/cid/opac_css/index.php?lvl=notice_display&id=182